A study published by the American Academy of Neurology found that heavy drinkers have an increased risk of brain lesions and signs of brain injury, including hyaline arteriolosclerosis and tau tangles. Heavy drinking was also associated with lower brain mass ratio and worse cognitive abilities.
Researchers have developed a novel wearable brain scanner that measures high frequency brain waves, revealing changes in E-I balance with age. This new technology allows for unprecedented precision in studying brain function in young children, potentially leading to better understanding of neurodevelopmental disorders like autism.
Researchers created an atlas of the brain's mitochondria, revealing that younger brain regions have more specialized mitochondria for efficient energy production. The study provides a new perspective on the role of energy in brain health and may lead to new approaches for treating neurological and psychiatric disorders.
A new digital 'translator' for brain studies enables researchers to map the brain in a standardized way, facilitating discoveries and treatments for various disorders. The open-source software allows for the comparison of brain imaging data with widely used brain atlases, promoting commonalities across findings.
Researchers at UCL identified key brain regions involved in remembering words, finding shrinkage in the front and side of the brain linked to difficulty recalling words. Detailed MRI scans showed a dispersion network for creating and storing word memories, crucial for understanding epilepsy conditions.
The Open Brain Institute launches a groundbreaking platform to simulate and study digital brains, empowering researchers to explore brain complexity and diseases. With its virtual neuroscience laboratories, the OBI enables global collaboration and access to cutting-edge virtual labs.
Researchers are testing a brain pacemaker to treat severe alcohol and opioid addiction, aiming to develop effective treatments and understand the brain mechanisms driving addiction disorders. The trial, known as Brain-PACER, uses deep brain stimulation to modulate brain activity and cravings.
Mayo Clinic researchers have developed a new way to more precisely detect and monitor brain cell activity during deep brain stimulation, a common treatment for movement disorders. The study uses custom algorithms to record broadband signals associated with hand movement in patients undergoing awake DBS surgery.
Neuroscientists Michelle Monje and Frank Winkler's groundbreaking discoveries show that neural activity promotes glioma initiation, growth, and treatment resistance. Their findings have transformed our understanding of brain cancer biology and offer new opportunities for treatment.
A new study published in Nature Materials demonstrates a lipid nanoparticle system capable of delivering messenger RNA to the brain via intravenous injection. The technology could pave the way for future treatments for conditions like Alzheimer's disease and drug addiction.
A new study led by researchers at Mass General Brigham suggests that different brain regions activated by creative tasks are part of one common brain circuit. People with brain injuries or neurodegenerative diseases may have increased creativity due to changes in this circuit.
The Center for BrainHealth hosts its third annual BrainHealth Week, offering simple tools and effective measurements for proactively increasing brain fitness and performance. A recent national survey reveals that 75% of people do not know how to promote brain gains, which BrainHealth Week aims to address.
A new study from the University of Southern Denmark reveals that the brain's self-healing abilities are hindered by inflammation after a stroke. The researchers mapped specific cells that play a central role in rebuilding myelin, but found gender differences in how men and women respond to injuries.
Scientists at the Allen Institute have identified specific cell types in the brain that undergo major changes with age, which could lead to new treatments for age-related brain diseases. The study provides a detailed map of brain cells affected by aging and highlights potential connections between diet, inflammation, and brain health.
Researchers at DGIST have developed a novel brain stimulation technology using an ultra-small coil to stimulate specific areas of the brain with high precision. This approach eliminates the need for large devices and minimizes risk of brain tissue damage.
A study found that soccer heading causes structural brain abnormalities similar to those seen in CTE, affecting the frontal lobe and verbal learning. The research suggests repeated head impacts may harm brain health even without serious injury.
Researchers at DGIST have developed a fully embedded wireless brain neural signal recorder that enables real-time recording of brain neural signals in non-human primates. The system uses wireless power transmission and communication to record brain activity during natural behaviors, such as eating or moving freely.
Researchers at Rutgers University have uncovered how various brain cell types work together to form large-scale functional networks in the human brain. The study found that certain cell-type distributions align with specific networks in the brain's cortex, highlighting a connection between cellular underpinnings and brain function.
The article advocates for traumatic brain injury (TBI) to be considered a chronic condition, requiring coordinated care throughout an individual's lifetime. This approach can improve patient outcomes and support for both patients and their families.
Researchers found that improved blood sugar control significantly impacts brain health, slowing down age-related brain atrophy by up to 50%. The Green Mediterranean Diet, rich in polyphenols, shows promise in supporting metabolic and brain health.
Researchers mapped how HSV-1 enters the brain, infects critical regions, and triggers neurological diseases. The virus was found in areas controlling vital functions, such as sleep and movement, and interacted with immune cells that led to chronic inflammation.
Researchers at Seoul National University have developed a non-invasive micro-shockwave therapy that safely stimulates the brain for nerve regeneration, showing activation of neurons and behavioral improvements. The therapy targets specific brain areas without causing damage, opening new horizons in non-invasive brain disorder treatment.
A longitudinal study tracked one person's brain activity for five months, revealing how daily life affects brain function. The research found that physical activity positively influences brain regions, while subtle shifts in mood and heart rate leave lasting imprints for up to fifteen days.
A team of scientists has successfully mapped the entire brain of Drosophila melanogaster, a fruit fly, using electron microscopy dataset and connectome analysis. The complete map will help researchers understand how different circuits work together to control behaviors like motor control, courtship, and decision-making.
Researchers at University of Pittsburgh discover that deep brain stimulation instantly improves arm and hand strength and function weakened by traumatic brain injury or stroke. The therapy stimulates the motor thalamus, a key relay hub of movement control, and significantly improves activation of muscles and grip force.
The BICAN Rapid Release Inventory provides early access to single-cell transcriptomic and epigenomic profiles from humans and other mammalian species. This open data release aims to accelerate discoveries in neuroscience by facilitating collaboration and data reuse among researchers.
Researchers have created the first map of a human brain over the course of pregnancy, documenting changes in gray and white matter. These findings suggest that the adult brain is capable of undergoing extended periods of neuroplasticity, which may support behavioral adaptations tied to parenting.
A new Northwestern Medicine study identifies critical language connector sites in the cerebral cortex that work together to produce language. These sites serve as connectors between subnetworks of people, serving a similar function for language in the brain.
Researchers have successfully manipulated brain waves during rapid eye movement (REM) sleep using sound stimulation, which may help improve cognition in individuals with dementia. The study found that stimulating brain waves could increase their frequency, offering a promising new approach for treating the condition.
A new AI algorithm, DPAD, developed by Maryam Shanechi's lab, can dissociate brain patterns related to specific behaviors, improving brain-computer interfaces for paralyzed patients. The algorithm can also discover new patterns in the brain that may be missed by prior methods.
A new Diffusion-based Graph Contrastive Learning (DGCL) method constructs brain networks with unique features, capturing key connections and eliminating redundant ones. DGCL outperforms existing tools in terms of efficiency and prediction accuracy for brain disease analysis.
Researchers at Houston Methodist have developed a more accurate way to deliver life-saving drug therapies to the brain, using an electric field to infuse medicine into specific targets. This innovation has the potential to improve gene therapy and tumor treatment, as well as treatment for traumatic brain injury and degenerative diseases.
Researchers found that word-specific brain activity peaks in speakers before speaking and corresponding spikes appear in listeners' brains after hearing the same words. The study suggests a shared model-based linguistic space for transmitting thoughts from brain to brain in natural conversations.
A new drug has shown promise in clearing HIV from the brain by targeting infected cells and reducing viral load. The treatment, BLZ945, successfully cleared the virus from brain tissue, providing a potential new avenue for HIV treatment.
Researchers have developed Nano-MIND technology, which uses magnetism to selectively activate specific deep brain neural circuits, modulating complex brain functions such as cognition and emotion. The technology has been successfully tested in animals, demonstrating its potential to regulate feeding behaviors and maternal instincts.
Researchers used advanced brain imaging techniques to identify key regions and networks involved in creative thinking. The Default Mode Network (DMN) was found to play a crucial role, with activity originating from the DMN before being evaluated by other brain regions.
A team of researchers has created a molecular atlas of the human brain's vasculature, revealing how endothelial cells regulate interactions between the bloodstream and surrounding tissues. The study provides insights into the growth patterns of blood vessels in early development, adulthood, and disease stages.
Researchers have identified a cellular mechanism that detects when the brain needs an extra energy boost to support its activity. This discovery could lead to new therapies for maintaining brain health and longevity by targeting impaired brain energy metabolism, a process accelerated in ageing and neurodegenerative diseases.
Researchers have recognized the dynamic and active role of brain extracellular space (ECS) in regulating neural activity. Dysregulation of ECS contributes to neurological disorders, suggesting therapeutic modulation as a novel treatment pathway.
Researchers have developed a novel platform that captures protein expression, cellular morphology, neural projection, and synapse distribution in large-scale human brain tissues. The system preserves cellular architecture while enabling detailed imaging and analysis of whole human brain hemispheres.
A study led by researchers from the University of Arizona Cancer Center identified a biological mechanism that could lead to more effective treatments for breast cancer that has metastasized to the brain. By targeting the autophagy pathway, the researchers were able to disrupt breast cancer cells' ability to form brain metastases.
Researchers have created the world's first human mini-brain that incorporates a fully functional blood-brain barrier, mimicking human neurovascular development. This breakthrough model promises to accelerate understanding and treatment of brain disorders like stroke, cerebral vascular disorders, and Parkinson's disease.
The study provides a comprehensive macaque brain atlas, MacBNA, that characterizes profiles of whole-brain regions, including connectivity, anatomy, and geometric topology. This atlas will aid in understanding brain function, development, and evolution, and can be used to transfer information from monkey brains to human brains.
Researchers have engineered an AAV that efficiently crosses the blood-brain barrier and delivers genes to the brain in humanized mice. This could lead to new treatments for severe genetic brain disorders with no current cures or few treatment options.
A team of neuroscientists proposes a framework to address the complex challenges of brain health, environment, and sustainability. The 'brain economy' concept aims to create a stronger future by reversing brain capital loss, which affects cognitive abilities and socioemotional stability.
DPABINet enables users to construct brain networks, conduct graph theory analysis, and perform statistical analysis with a single click, eliminating the need for programming expertise. The platform enhances brain structural network research derived from diffusion-weighted imaging, providing a robust analysis framework.
Researchers at The University of Tokyo successfully connected lab-grown brain-mimicking tissue using axonal bundles, mimicking natural brain connections. This breakthrough enables the study of complex brain networks and their role in various neurological and psychiatric conditions.
A new study found that mums with insecure attachment traits showed more brain-to-brain synchrony with their children, while fathers and children had stronger brain-to-brain synchrony. The research suggests that high or low synchrony can signal interaction difficulties in families.
Researchers at Hiroshima University explore the ethics of growing brain organoids from human fetal brain cells, highlighting concerns over consciousness, informed consent, and medical applications. The study emphasizes the need for a global regulatory framework to navigate the complex ethical landscape of fetal brain organoid research.
Researchers at DGIST have created highly durable brain electrodes made of soft and elastic materials, sticking well to the curved brain surface. These electrodes can maintain stable performance over long-term use, enabling various applications in brain–machine interfaces and electronic medical devices.
Researchers discover a significant association between chronic knee pain and accelerated brain aging, highlighting the need for early detection and intervention strategies. Brain regions critical for cognitive function show increased signs of aging in individuals with chronic musculoskeletal pain.
A new study found that human brains are getting larger, with participants born in the 1970s having 6.6% greater brain volume and almost 15% larger brain surface area than those born in the 1930s. This increased brain size may lead to a higher brain reserve, potentially reducing the overall risk of age-related dementias.
A new study found that a viral infection can cause cognitive impairments by damaging the blood-brain barrier, leading to memory loss and learning difficulties. Researchers developed a gene therapy that stimulated the Wnt/beta-catenin pathway to prevent this damage and improve cognitive function in mice infected with SARS-CoV-2.
Researchers at the University of Galway have developed a new method for improving stem cell-based brain repair therapy for Parkinson's disease, which shows promising results in enhancing survival and maturation of cells in the brain. The technique uses a collagen hydrogel to support and protect the cells after transplantation.
Researchers have developed a cost-effective method to spatially characterize and map brain epigenomes, providing a comprehensive map of the brain's biology at genome scale. The approach enables understanding of gene activity outside of DNA sequences and has implications for treating brain disorders.
A new study by researchers at the University of Minnesota reveals that non-invasive brain stimulation can change a specific brain mechanism related to human behavior. The technique, called transcranial alternating current stimulation, modulates brain activity by shifting when brain cells are active.
A team of researchers from the Medical University of South Carolina has discovered a novel protective response by which the brain naturally repairs itself after traumatic brain injury. Protein p17 plays a crucial role in this process, triggering the restorative mechanism of mitophagy to remove damaged tissue and initiate healing.
Researchers found that different areas of the brain start with a similar organization in early development, using a shared blueprint to guide neural growth. This suggests that neurodevelopmental disorders may act similarly across diverse brain areas.
A preliminary study found that people with headaches after concussions tend to have higher levels of iron in areas of the brain, suggesting damage to brain cells. The more concussions and frequent headaches individuals experience, the greater the likelihood of increased iron accumulation in certain brain regions.
Scientists at Washington University School of Medicine discovered that neurons coordinate to produce rhythmic waves that propel fluid through dense brain tissue, washing the tissue in the process. This finding has implications for delaying or preventing neurodegenerative diseases by enhancing the brain's cleaning abilities.