A study has overcome a key hurdle to the use of nanorobots powered by lipases, enzymes that play essential roles in digestion. By modulating motor speeds, researchers have broadened the potential biomedical and environmental applications of these devices.
Researchers have developed core-sheath polymer fibers that combine strength with bioactivity, enabling various biomedical applications. The fibers can be tailored to specific needs by carefully selecting inner and outer layer materials, and can even include antiviral agents or drugs.
Biomedical researchers at Georgia State University have identified a novel method for eradicating rotavirus and other viral infections using interleukin-18 and interleukin-22. The study shows that these cytokines can rapidly and completely eliminate viruses from intestinal epithelial cells, even in compromised immune systems.
Researchers at Pennington Biomedical Research Center will investigate how the SGK1 enzyme regulates beta-cell mass when more insulin is needed. The study aims to understand how beta-cell growth mechanisms influence insulin release, potentially leading to new medications for diagnosing and treating metabolic diseases.
The GDPR's restrictive approach to international data transfers is hindering global biomedical research, including essential COVID-19 studies. The authors propose amendments to address this issue, ensuring the balance between individual privacy and societal benefits in research contexts.
The Pew Charitable Trusts has awarded funding to six interdisciplinary research teams to tackle some of biomedicine's toughest challenges. The teams will explore neurological mechanisms behind psychopathy, map protein complexes in Plasmodium falciparum, and investigate steroid hormones' role in Alzheimer's disease.
Researchers are developing a novel, noninvasive method to target and kill cancerous cells in breast tissue using nanoparticles and ultrasound. This approach, nanoparticle-mediated histotripsy (NMH), aims to improve the safety of treatment for metastatic breast cancer patients by reducing harsh side effects associated with chemotherapy....
Researchers have developed a new approach to machine learning combining ensemble methods and deep learning to diagnose cancer, predict viral attacks, and revolutionize molecular biology. This emerging field has the potential to transform bioinformatics and biomedical sciences.
Biomedical engineers at Duke University have created artificial membrane-less organelles within human cells by controlling the phase separation of emerging class of proteins. This advance enables precise tuning of a single property to modulate existing cell functions or create new behaviors.
The Purdue team created a fully implantable radio-frequency transmitter chip that consumes the lowest amount of energy per digital bit published to date. It enables real-time biophysiological data monitoring for conditions like glaucoma and heart disease, eliminating the need for batteries or frequent recharging.
A University of Sydney team has developed a plasma technology to attach hydrogels to polymeric materials, allowing for better interaction with surrounding tissue. The technology has shown promising results in tests using biomolecules found in the body.
The two institutions will recruit underrepresented minority PhD students into their biomedical research programs, building a pipeline of minority scientists in the Cleveland area. The grant aims to increase diversity and inclusion in STEM fields, promoting creativity, problem-solving, and innovation.
The Pew Charitable Trusts has selected 10 postdoctoral fellows from seven Latin American countries to conduct research in the US. The fellows will explore various biomedical topics, including leukemia stem cells and HIV hiding inside host cells.
The Chan Zuckerberg Initiative is awarding $3.8 million to support essential open source software projects in biomedical research and clinical medicine. These grants will enable awardees to improve software tools, enhance collaboration, and advance biomedical science.
The National Institutes of Health has renewed funding for UC Davis's Mutant Mouse Resource and Research Center, providing $6.7 million over five years. The center will acquire new mouse strains and develop novel models to support biomedical researchers.
A comprehensive epigenetic study on human tumor organoids reveals their potential as a reliable model for cancer research. The findings validate the use of these samples in biomedical research and pharmaceutical development, opening up new avenues for discovering anti-cancer treatments.
Biomedical engineers at Duke University developed a massive fluid dynamics simulator to model blood flow through the full human arterial system, providing guidance for treatment plans. A new graphical user interface called Harvis allows clinicians to easily explore options without expertise in computer science.
Researchers at Texas Biomed launched a comprehensive multi-species study to identify the best animal model for COVID-19. The study includes four additional species and aims to pinpoint the most effective model for diagnostics, vaccines, and therapies.
A new adhesive method allows conductive polymer gels to adhere to a wide variety of surfaces, including glass and gold, even when exposed to moisture. This breakthrough enables the development of more durable and reliable biomedical sensors and implants.
The Vilcek Foundation is awarding $150,000 to three early-career immigrant researchers in biomedical science. The prizes recognize emerging professionals who have demonstrated significant accomplishments early in their careers.
A new model of chromosome X-linked adrenoleukodystrophy in C. elegans has been identified, accelerating research on the disease and its potential pharmacological targets. The model points to glial cells as responsible for neurological damage, with oxidative stress caused by mitochondria being a major cause.
Scientists use electrospun synthetics to mimic the extracellular matrix, standardizing research conditions. The study reveals that different types of breast cancer cells grow best in specific cellular environments.
A pilot program launched by the Berlin Institute of Health aims to enhance the quality and value of translational research through training, tools, and monetary incentives. The QUEST Center's initiative seeks to address concerns over transparency and reproducibility in biomedical science.
The University of Washington's new WE-REACH center aims to support biomedical entrepreneurs and provide project funding for up to six startups per year. The center, funded by the NIH, will focus on innovative disease treatments, new drugs, and health technologies.
Xu is being honored for her efforts to recruit women, underrepresented minorities, and first-generation college students to the fields of chemistry, biochemistry, and biomedical sciences and engineering. She has led a laboratory pursuing research at the interface of chemistry, biology, engineering, and medicine.
A new photoacoustic tomography technique aims to improve the detection and measurement of hypoxic-ischemic brain injuries in preterm newborns without sedation or radiation. The technology has the potential to revolutionize neonatal brain imaging management, enabling earlier treatment and improved outcomes for patients.
A new study published in Family Practice shows a significant gender gap in biomedical paper publication rates, with women accounting for 48% of first authors in primary health care journals. The study found that women are less likely to publish articles on trials and have fewer research grants, contributing to the disparity.
The Wellcome Trust has established a translational partnership with Charité and the Berlin Institute of Health (BIH) to maximize translational medicine's benefits for patients and society. The partnership aims to raise biomedical research quality, improve regulatory understanding, and establish incentives for translational research.
Researchers identified Annexin A6 as a key factor in cholesterol regulation and potential therapeutic target for diseases caused by lipid accumulation. The study shows that silencing AnxA6 can redirect cholesterol to other cell compartments, potentially treating conditions like Niemann-Pick type C1 and various cancers.
A new report recommends that researchers use expert reviews and computational Big Data approaches to select high-quality chemical probes. The report highlights the value of resources like the Chemical Probes Portal, which provides assessments on 192 chemical probes for 181 different proteins of interest.
A study by Oregon State University found that 18 batches of supposedly pure human blood serum contained caffeine, cough medicine, and anti-anxiety drugs, highlighting potential issues with contaminated blood transfusions. The research also tested for interactions between botanical supplements and prescription drugs.
A team led by biomedical engineer Kam Leong has received a $3.2 million NIH grant to develop efficient, noninvasive gene editing methods for the brain. The goal is to overcome current inefficiencies in delivering CRISPR-based gene editing elements to the brain and treat devastating diseases like Alzheimer's.
Biomedical engineers at Duke University have developed a new method to create stable IDP-based materials by controlling environmental triggers. This allows researchers to harness the phase transition properties of IDPs to build novel materials for drug delivery, tissue engineering, and regenerative medicine.
The UTSA/NIH program aims to increase diversity in the biomedical sciences by training underrepresented students in research skills and experience. High-achieving freshmen from South Texas high schools will be recruited for a five-year grant-funded program.
Marshall University has received a five-year, $17 million award from the National Institutes of Health (NIH) to continue its biomedical research efforts in West Virginia. The WV-INBRE program aims to enhance biomedical research capacity and provide access to resources for undergraduate students.
The Biomedical Engineering Society has recognized Weiqiang Chen's original research on single-cell mechanical allostasis, a biological process that drives cells to reach a new equilibrium. His work employs principles of mechanical engineering and physics to identify the state of individual cells.
The NIH awarded UTEP's BUILDing SCHOLARS program a $15.2 million grant to train the next generation of biomedical researchers in the US Southwest, focusing on cancer, addiction, environmental health, and more. The program aims to increase diversity in the biomedical research workforce.
Researchers at Texas Biomedical Institute are studying lung macrophages and their role in TB infection, with the goal of developing a new set of biological pathways critical to the body's response. The findings could lead to a new strategy for host-directed therapy and potentially cure TB.
Researchers at Texas Biomed continue testing Ebola therapies and vaccines in human clinical trials, motivated by promising preclinical data. The goal is to positively impact human lives with effective treatments, building on previous studies involving nonhuman primates.
Researchers have developed a new flexible membrane that guides cracks away from critical components, increasing the functional lifespan of biomedical devices. The study, led by Binghamton University Associate Professor Guy German, uses human skin topography as a model to direct cracks in the best way possible.
Researchers have developed a new CRISPR technology to accurately regulate and edit genomes in human cells, opening up nearly 90% of CRISPR-Cas systems. This approach has shown promise for biomedical research, gene therapies, and other applications.
The Pew Charitable Trusts has awarded grants to six interdisciplinary research teams, combining expertise in virology, epigenetics, microbiology, and developmental biology to advance groundbreaking discoveries. The research projects focus on understanding complex biological processes, such as viral manipulation of host cells, genetic v...
Researchers at Texas Biomedical Institute have discovered that lung-specific chronic immune activation is responsible for the progression of disease in HIV patients. This dysfunction leads to a constant production of cytokines and chemokines, dysregulating the body's ability to fight off other infections.
Experts from NIAID urge biomedical research community to refocus on STI research, emphasizing the need for innovative diagnostics, therapeutics, and vaccines. The authors highlight the critical need to address antimicrobial resistance and cooperation among researchers, healthcare providers, and community clinics.
The ReBUILDetroit program, a partnership between University of Detroit Mercy and Wayne State University, has received a $19.4 million NIH grant renewal to provide scholarships and stipends for students enrolled in the program. The program aims to encourage underrepresented students to pursue careers in biomedical research.
The University of Oklahoma Health Sciences Center has received a $18.7 million grant to expand biomedical research on complex diseases like cancer and diabetes. The grant aims to develop new medical devices and treatments while building a pipeline for the next generation of researchers and healthcare professionals.
A team of researchers at Texas A&M University has developed a way to control the hydrophobicity of surfaces inspired by nature, which could have widespread applications in the biomedical field. The 'nanoflower' design uses atomic defects in nanomaterials to repel water and clean surfaces.
A new study found that biomedical bleeding can reduce spawning activity and alter biological rhythms in female horseshoe crabs, potentially impacting reproduction and population levels. The research suggests that the recovery from bleeding may also affect energy allocation towards spawning.
A dietary supplement called L-serine has been shown to improve the neuronal function of a patient with a mutation associated with atypical Rett syndrome. The study, led by Dr Xavier Altafaj, found that supplementation with L-serine reversed alterations caused by the mutation and improved the patient's motor and communicative abilities.
Lillian Fritz-Laylin is a recipient of the Pew Scholars Program in Biomedical Sciences, which includes four years of funding to investigate complex mechanisms of biology. Her research focuses on understanding how cells deploy actin for various functions, with implications for disease prevention and progression.
Geetu Tuteja, an assistant professor at Iowa State University, has been selected as a Pew Scholar to study genetic networks that establish a healthy connection between embryos and their mothers. She will receive a four-year, $300,000 grant to conduct biomedical research aimed at advancing human health.
The Pew Charitable Trusts has funded research for 10 postdoctoral fellows from six Latin American countries to conduct studies in the US. The researchers aim to advance biomedical science and expand scientific expertise in their home countries.
The Pew Scholars Program in the Biomedical Sciences supports young researchers investigating connections between embryos and their mothers, tick-borne diseases, and sensory information processing. The program aims to drive significant scientific discoveries by investing in promising scientists at the beginning stages of their careers.
The Kentucky Biomedical Research Infrastructure Network (KBRIN) has received a $18.2 million grant from the National Institutes of Health to enhance biomedical research in Kentucky. The network provides access to equipment, collaborative networks, and funding for early-stage researchers.
The Department of Defense is funding a study on a promising experimental Zika vaccine at Texas Biomedical Research Institute. Researchers are working to develop a vaccine that can protect pregnant women from the virus and its devastating birth defects.
The Maine INBRE program has received a $18 million grant from the National Institute of General Medical Sciences to strengthen biomedical research and research training in Maine. The program provides opportunities for undergraduate students and young faculty members to gain research experience and skills, leading to advancements in hum...
Researchers used high-throughput screening to design new multi-component alloys for biomedical applications, achieving efficient composition optimization and improved mechanical properties. The study employed a novel approach combining co-sputtering technology with physical masks to create compositional gradients.
The NIH is funding a new study that aims to discover the link between early life blood sugar levels and middle-aged brain health. The Bogalusa Heart Study will use advanced imaging techniques to assess brain health in participants, and the results could lead to new guidelines for managing childhood blood sugar levels.
Six University of Houston students have earned NSF graduate research fellowships, pursuing research in augmented reality, Mars geology, biomedical engineering, and more. The awards recognize outstanding STEM graduates who will receive a three-year stipend and education allowance.
The Logan Science Journalism Program allows established science and health journalists to participate in hands-on research training at the MBL. Fellows conduct biomedical or environmental research, discovering key concepts and techniques in cell biology, genomics, and ecosystem dynamics.