The UVA Weber Symposium will discuss the latest research and advancements in metastasis, a complex area of cancer research and care. The event will bring together top scientists and physicians to present findings on cancer metastasis, genetics, and treatment considerations.
A new, incisionless liver cancer treatment called histotripsy was associated with low rates of laboratory toxicity and procedural complications in a real-world review of 972 patients. However, the study found that 11% of patients died within 30 days, suggesting that advanced cancer and overall disease burden may be contributing factors.
The new guidelines, developed by leading experts, focus on improving sepsis care by strengthening systems for diagnosis, treatment, prevention, and quality improvement. Emerging technologies, such as next-generation diagnostics and artificial intelligence, are also being explored to enhance sepsis care.
A study found that trends in 26 blood tests were associated with cancer risk in patients with unexplained weight loss. Researchers identified specific trends linked to lung and prostate cancers, suggesting that monitoring changes in routine blood test results could identify patients who would benefit from additional cancer testing.
Prostate cancer affects 1 in 8 men, with 60% diagnosed in men 65 and older. Clinical trials like Alliance's help improve early detection and treatment, reducing mortality rates by half since 1993. These trials also explore new treatments and survivorship strategies.
The Alliance for Clinical Trials in Oncology emphasizes the significance of clinical trials in advancing breast cancer treatments and early detection. The organization's work has led to a 44% decline in breast cancer mortality rates among women since 1989.
A new book by University of Virginia Health System expert Daniel J. Cox outlines a practical alternative to medication for managing pre-diabetes and type 2 diabetes. The GEM program emphasizes smart eating, physical activity, and listening to the body to regulate blood sugar levels.
Researchers developed a framework to integrate AI into hospitals, emphasizing patient care, staff experience, and economic sustainability. The Total Mission Value framework aims to ensure high-quality patient care remains the top priority amidst AI's transformative potential.
A new review of current research highlights the importance of culturally grounded approaches to food systems literacy in addressing global hunger and malnutrition. The study suggests that Indigenous knowledge and participatory methods can improve food systems resilience and support communities to maintain traditional food practices.
A new study found that simple weekly electronic symptom check-ins with care teams significantly improves the quality of life for individuals undergoing treatment for advanced cancer. The benefits were notable among patient groups that historically faced barriers to care, including Black patients and those with less formal education.
A recent study found that US women's healthcare providers became more politically engaged following the Dobbs decision, with a significant increase in voter turnout compared to other physicians. The research suggests that the shift was driven by the direct impact of the policy change on their work and patients' lives.
Scientists have identified a unique chimeric RNA called UBA1-CDK16 that plays important roles in women's blood cell development and disease severity. The findings suggest the chimeric RNA may serve as a natural brake to protect women from excessive autoimmune activity.
Researchers found that over-the-counter probiotics contain only 36 unique species of bacteria, with most common species being forms of Lactobacillus. The analysis suggests a lack of consistency in the combination of species used to support gut health and vaginal health claims.
Researchers found that patients with Medicare Advantage insurance were more likely to receive certain types of stroke-preventing care and recover faster from strokes. In contrast, patients on traditional Medicare received more intensive post-stroke care and rehabilitation.
The University of Virginia has joined SPARK GLOBAL to leverage resources and expertise in accelerating the development of new medicines. This collaboration aims to reduce time from lab discoveries to clinic trials, delivering tangible healthcare solutions to patients.
A new study by the University of Southampton has found that reusable catheters are just as safe for patients as single-use ones and do not increase the risk of urinary tract infections. The study followed hundreds of patients for a year and discovered that those who tested reusable catheters used 35 per cent fewer antibiotics.
A major international study has identified ways to detect patients with hypertrophic cardiomyopathy at serious risk of sudden death, heart failure or other dangerous outcomes. The findings will help save lives by improving the ability to determine who is at greatest risk and spare low-risk patients from unneeded heart implants.
Scientists at the University of Virginia Health System have developed a suite of AI-powered tools, called YuelDesign, YuelPocket and YuelBond, to transform how new drugs are created. These tools can design drug molecules tailored to fit their protein targets exactly, even accounting for protein flexibility.
A QUT study found wide variation in GP involvement in voluntary assisted dying (VAD) in Queensland, highlighting the need for improved remuneration, streamlined processes, and broader education. GPs reported confusion about who was eligible and how to discuss VAD with patients.
A new study published in PLOS Medicine found that power outages in the US are associated with increased emergency hospital visits for older adults, particularly for cardiovascular and respiratory diseases. The study estimated that 4,246 additional hospitalizations occurred in 2018 among adults over 65 due to power outages.
A $3.4 million NIH grant will fund a semi-automated feedback system to support people tracking diet, exercise, and weight in weight-management programs. The system aims to provide personalized feedback to increase tracking and weight loss success.
The Alliance trial explores the combination of zanubrutinib and sonrotoclax for CLL treatment, aiming to send cancer into remission and allow patients to stop treatment earlier. The study has the potential to be life-changing for patients and their families, reducing the burden of ongoing therapy and improving quality of life.
Severe COVID-19 and influenza infections can prime the lungs for cancer development, according to new research. Vaccination, however, largely prevents these changes, suggesting a reduced risk of lung cancer.
The Alliance for Clinical Trials in Oncology is spotlighting new trials for colorectal cancer in March, focusing on early detection methods and treatments for treatment delays and loss of appetite. The trials aim to improve patient outcomes, with several enrolling patients with newly diagnosed colon or rectal cancer.
A study by University of Virginia Health System researchers found that Medicare Advantage patients had better access to preventive care and rehabilitation after a stroke, leading to faster recovery times. In contrast, traditional Medicare patients were less likely to receive these services due to prior authorization requirements.
The Ann Arbor Guide provides two algorithms for triaging adults with suspected UTIs, one for non-pregnant women and the other for men. It also emphasizes the importance of accurate testing and treatment to prevent overuse of antibiotics and antibiotic resistance.
A three-year study by the University of Plymouth is investigating why fewer overseas-trained doctors become GPs and consultants in the NHS. The project seeks solutions at individual, trust, and national levels to support international medical graduates' career progression.
A recent study by Willa Granger examines the transformation of nursing homes in postwar America, tracing the development of the modern nursing home industry through the lens of the Americana Corporation. The research reveals how federal programs and corporate models reshaped eldercare, prioritizing scale and replication over community ...
The US needs a new strategy for insurance coverage and access to cell and gene therapies due to high up-front costs. In contrast, Europe has approved 19 CGTs with most being reimbursed within two years of approval based on demonstrated added therapeutic value.
A new RNA-based therapy targeting Marfan syndrome shows promise in treating the genetic disorder, which can lead to aortic aneurysms and be fatal. The therapy, developed by Mizzou researcher Dunpeng Cai, aims to correct mutated RNA for those with Marfan syndrome.
A portable device using machine learning can detect signs of concussions in real-time, providing a more objective way to assess injuries. The Mizzou Point-of-Care Assessment System combines a force plate, depth camera and interface board to track movement, balance and reaction times.
The RenewU program provides evidence-based interventions to prevent burnout and promote resilience in healthcare providers. The toolkit offers mental health support, stress management, and physical wellness resources, including yoga and exercise guides.
A recent study published in CANCER reveals that many patients with advanced cancer report receiving treatment that focuses on longevity rather than comfort. Despite this mismatch, the treatment did not appear to extend life for those who did not want it. The research highlights the importance of open conversations between doctors and p...
Researchers envision AI-powered systems that identify patients at risk of mental health struggles, provide continuous psychological monitoring and tailor interventions. AI can also overcome barriers to mental health care by delivering support exactly where and when it's needed, including rural areas.
A recent study by researchers at the University of Missouri has made a groundbreaking discovery using patient's own cartilage cells to aid in healing after hip surgery. The research team successfully cultured and expanded cartilage cells, or chondrocytes, in the lab, paving the way for future clinical applications.
A new article by Dr. Leonard Berry of Texas A&M University argues that values-driven listening can improve care and heal the healthcare system. The authors identify six types of listening, including proximate, curious, earning trust, aided by design, empowering, and fostering resilience, which contribute to better care.
A study of 62,839 people diagnosed with non-metastatic prostate cancer in Sweden found that those treated according to NCCN Guidelines were likely to survive their cancer for their remaining life-expectancy. Those with low- and intermediate-risk cancer were six times more likely to die of other causes than prostate cancer.
A special issue of Journal of Intensive Medicine provides key insights into selecting optimal non-invasive respiratory support strategies for AHRF, featuring review articles and original research. The collection offers guidance on the efficacy of HFNC, CPAP, NIV, and awake prone positioning to improve patient outcomes.
A new book written by an international team from Carnegie Mellon University and the University of Oxford argues that data-driven decision-making can improve healthcare outcomes. The authors explain how analytics can be used to optimize hospital operations, manage bed allocation, and improve treatment efficiency.
Scientists have identified a brain molecule called NEAT1 that appears to play a central role in triggering light sensitivity (photophobia) during migraines. By disrupting the normal balance of nerve signaling and pain regulation, NEAT1 makes nerves more sensitive to light.
The National Comprehensive Cancer Network (NCCN) is joining forces with global organizations to address gaps in cancer control plans, promoting data-driven decision-making and comprehensive implementation. The Cancer Planners Forum aims to optimize care for people touched by cancer globally.
The University of Texas at Arlington offers pre-health students valuable hands-on experience through an innovative collaboration. Students in SCIE 4304 participate in immersive clinical simulation lab at the UTA Smart Hospital, developing rudimentary clinical skills and overcoming imposter syndrome.
Researchers at Lancaster University discovered a new type of vaccine-specific scepticism, where some people perceive COVID-19 vaccines as 'not a vaccine' compared to MMR. This phenomenon may also apply to the flu vaccine, highlighting the need for clear public health messaging.
A groundbreaking study analyzed data from over 78,000 cancer patients to identify nearly 800 genetic changes impacting survival outcomes. The research also discovered genes significantly associated with survival in various cancers, such as breast, ovarian, skin, and gastrointestinal cancers.
Researchers have identified a key protein called Apex1 as a potential therapeutic target for stopping the immune system from attacking itself. By inhibiting this protein, harmful T cells that cause autoimmune diseases and allergies can be eliminated.
Researchers have developed a cost-effective and easily reproducible point-of-care testing device that can accurately measure cortisol levels in the blood. The device uses iridium oxide nanoparticles to improve stability, sensitivity, and selectivity, allowing for commercial use.
A recent study published in JAMA Network Open reveals that nearly half of long-term antidepressant users can successfully taper off their medication with the help of general practitioner support and internet or telephone helplines. The study found lower rates of depression, fewer withdrawal symptoms, and improved mental wellbeing among...
A new Cochrane review suggests that taking zinc may reduce the duration of common cold symptoms by around two days, but the evidence is not conclusive. Common side-effects include bowel problems, nausea, and unpleasant taste.
SourceCochrane·JournalCochrane Database of Systematic Reviews·TypeSystematic review·DateMay 8, 2024
The General Medical Council's definition of international medical graduates (IMGs) is being challenged as it overlooks doctors from the European Economic Area (EEA). A commentary argues that the term should include all doctors practicing in the UK with primary medical qualifications from outside the UK, including those from EEA countries.
A new study found that voluntary collective isolation was unlikely to prevent rapid spread of COVID-19 among the Tsimané, a small-scale Indigenous society in remote Amazonia. The simulation predicted nearly identical rates of infection in real-world data, highlighting the need for targeted interventions and medical resources
A new study published in PLOS Global Public Health found that 70% of ayahuasca users experienced physical health adverse effects, while 55% reported mental health concerns. Most adverse events were reported as mild and temporary, with only 2.3% requiring medical attention.
Researchers uncover the origins of Kampo, tracing it back to 8th century Chinese monk Jianzhen's herbal medicines and prescriptions. These findings show that Kampo has been integrated into Japan's healthcare system for centuries, influencing traditional Japanese medicine.
A recent study published in PLOS ONE found that opioid prescriptions declined for US patients with both cancer and non-cancer pain between 2012 and 2019. The proportion of people receiving any opioid prescription dropped from 49.7% to 30.5% for non-cancer pain and from 86.0% to 78.7% for cancer pain.
A multi-center study assesses medicinal mushrooms and Chinese herbs for therapeutic benefit in treating acute COVID-19 infection. The MACH-19 trial evaluates the safety and feasibility of two investigational compounds, one in capsule form and another as a Chinese herbal formula.
A joint UC study found that three-quarters of medical students believe conventional Western medicine would benefit from integrating more complementary and alternative medicine (CAM) therapies. The survey revealed that CAM can enhance patient care, improve treatment outcomes, and increase the effectiveness of healthcare systems.
A new study explores how consumers choose among health remedies and the consequences for a healthy lifestyle. Consumers prefer Traditional Chinese Medicine (TCM) when uncertain about an illness's cause or seeking an underlying cure, as it tolerates uncertainty better than Western medicine.
A study found that resident physicians feel insufficiently prepared to care for patients from different cultures, with significant gaps in cross-cultural education and mentoring. The survey results highlight the need for improved training programs to address racial and ethnic disparities in healthcare.