Articles tagged with Orthopedics
Researchers developed a novel 'Wikiguideline' approach to establish medical guidelines, leveraging online collaboration and high-quality data. The method was tested using osteomyelitis, an infection of the bone, and found sufficient data for only two recommendations: increasing oral antibiotic therapy and limiting therapy duration.
A study by researchers at the University of Pennsylvania School of Medicine found that mailing opioid disposal kits doubled the rate of safe disposal among patients who received them. The kits were provided to 235 patients after orthopedic or urologic procedures and resulted in the safe disposal of 480 unused tablets.
A study found no increased mortality risk or serious adverse outcomes in high-risk patients receiving tranexamic acid during IT fracture surgery. The medication, which promotes blood clotting, was also associated with a small decrease in blood transfusion risk.
Researchers at Lehigh University developed a new method to accurately gauge healing progress of bone fractures using 3D models. The model identifies the cutoff point between soft tissue and bone, allowing for more precise predictions of bone behavior during the healing process.
The UK National Osteoporosis Guideline Group has published a new guideline for the prevention and treatment of osteoporosis, which includes updated recommendations for vertebral fracture detection and anabolic treatment options. The guidance aims to improve service provision in both primary and secondary care settings.
A new Michigan Medicine study found that for children with a pelvic tilt and lower lumbar spine tilt of fewer than 10 degrees, the pelvis did not need to be included when inserting growing rods. This could help avoid painful complications such as skin breakdown and infection.
A bundled care Medicare program has led to reductions in some outcome disparities for Black patients compared to White patients undergoing hip and knee replacement surgery. The Comprehensive Care for Joint Replacement (CJR) Model has improved key outcomes such as hospital readmission rates, length of stay, and Medicare payments.
An international team of engineers has successfully bioprinted bone along with two growth factor encoding genes that help incorporate cells and heal defects in rats. The researchers used gene encoding PDGF-B and BMP-2, which encouraged cell multiplication and migration, resulting in a 40% increase in bone tissue creation.
Researchers at University of Oxford and Leeds found liposomal bupivacaine no more effective than current treatments for post-operative knee pain. The SPAARK Trial showed that the drug did not improve recovery or pain relief compared to bupivacaine hydrochloride alone.
A study led by University of Gothenburg researchers found that comprehensive preventive measures cut catheter-related urinary tract infections (UTIs) in frail elderly patients with hip fractures from 18% to 4%. The interventions included aseptic procedures, training videos, and knowledge testing.
A new study found that an orally absorbed tablet containing cannabidiol (CBD) effectively reduced post-operative pain after shoulder surgery without side effects. The study showed significant pain relief and higher patient satisfaction compared to placebo, highlighting the potential of CBD as a safe and effective pain management tool.
The Virtual WCO-IOF-ESCEO 2022 Congress will feature leading experts on osteoporosis, osteoarthritis, and musculoskeletal diseases, with a focus on new clinical research and advances in prevention and patient care. Prestigious awards will also be presented.
Professor Elaine Dennison has been awarded the IOF Olof Johnell Science Award for her significant work in musculoskeletal aging, osteoporosis, and metabolic bone diseases. She is recognized as an internationally renowned clinician, researcher, and educator.
Researchers developed a novel genetic barcode system to mark cancer cells with different gene modifications and image their characteristics. The Perturb-map platform identified specific genes controlling lung tumor growth, immune composition, and response to immunotherapy, offering new approaches for targeting anti-cancer drugs.
The World Congress on Osteoporosis, Osteoarthritis & Musculoskeletal Diseases (WCO-IOF-ESCEO) 2022 will discuss secondary fracture prevention. Global experts will provide clinical guidance and information on post-fracture care through various sessions.
Patients who discontinue biologic disease-modifying anti-rheumatic drugs (bDMARDs) before orthopaedic surgery are more likely to experience a disease flare following surgery. However, discontinuing bDMARDs does not appear to increase the risk of surgical site infections or delayed wound healing. The review and meta-analysis highlights ...
Researchers at Mayo Clinic developed a non-opioid pain management approach that provides equivalent or better pain control and patient satisfaction compared to traditional opioid regimens. This approach eliminates opioids after common sports surgeries, such as knee and shoulder procedures.
Researchers at Marshall University's Joan C. Edwards School of Medicine have successfully applied robotic arm technology to revision total knee arthroplasty, achieving well-aligned components and excellent range of motion in patients. The study utilizes computer-assisted technology to improve component positioning and reduce the burden...
A new review by the International Osteoporosis Foundation highlights the importance of comprehensive post-fracture care, including exercise, nutrition, physiotherapy, and patient education. The study concludes that individualized exercise approaches can improve recovery and reduce future fracture risk.
A new study published in NEJM Evidence reveals that exercise and patient education can provide similar results as surgery for young people with meniscal tears. The research compared surgical and non-surgical treatment options among 121 young individuals and found no significant difference in outcomes between the two groups.
A new Irish survey found that no trauma sites capture all fracture patients, with only 50% receiving osteoporosis medication within four months of a fracture. Implementing a national Fracture Liaison Service (FLS) would bring services in line with international standards and reduce hospital admissions.
A new care pathway has been shown to reduce long-term pain and improve quality of life for people after knee replacement surgery. The STAR care pathway is cost-effective and could potentially save the NHS up to £14 million per year.
A study found that 31.4% of trauma patients at Hospital das Clínicas in São Paulo, Brazil, tested positive for psychoactive substance use, including alcohol (23%), cocaine (12%), and marijuana (5%). The study contributes to the development of public policies to prevent accidents.
Fibrodysplasia ossificans progressiva (FOP) may be rooted in impaired and inefficient muscle tissue regeneration, which enables unwanted bone growth. This discovery could lead to new therapies targeting both extra-skeletal bone formation and muscle function.
A recent HSS study analyzed trends and complications in patients undergoing outpatient hip and knee replacements, finding no significant difference in readmission rates for hip replacements but slightly higher odds for knee replacements. The study suggests same-day discharge joint replacement is safe but requires additional monitoring.
The integration of optical sensing into orthopedic surgical devices has the potential to increase accuracy and improve outcomes in musculoskeletal repair. Researchers explore various types of optical sensing, including spectroscopy and imaging, to address unmet clinical needs in orthopedic surgery.
A new study suggests that combining two drugs can reduce postoperative opioid use and side effects in adolescents with scoliosis. The combination of intrathecal morphine and oral gabapentin provides more effective pain control, resulting in fewer side effects and lower narcotic consumption.
Researchers found that brain activity in children with arthrogryposis is different from healthy controls, with increased motor neuron activity and less precise movements. Non-invasive brain stimulation may be a possible rehabilitation strategy to help them start movements.
Researchers at INRS have developed a bioactive coating that mimics bone tissue using chitosan, collagen, and copper-doped phosphate glass. The coating promotes healing and reduces the risk of rejection, paving the way for improved orthopaedic implant success.
A new study found that COVID-19 lowered expenses for orthopaedic surgery residency applicants due to the elimination of in-person interviews and away rotations. The median total expenses decreased from $7,250 in 2020 to $2,250 in 2021, with significant savings seen in interview and away rotation costs.
A lighter, more robust knee brace for the elderly has been developed through a collaboration between Delsson and Nanyang Technological University. The X-Brace uses lightweight plastic and assistive springs to reduce weight by 30%, making it easier for patients to walk with less pain.
Researchers at Keck School of Medicine of USC have developed a stem cell-based bio-implant to repair cartilage and delay joint degeneration. The Plurocart implant successfully integrates into damaged articular cartilage tissue and survives for up to six months.
A LSU Health New Orleans study reports a nearly 70% decrease in morphine milligram equivalent (MME) per discharge opioid prescriptions for patients who underwent common lower extremity surgical procedures. The study also found a significant decline in new opioid prescriptions, from 50% in 2013 to 19.3% in 2018.
Researchers at the University of Oklahoma have discovered a new protein fragment that could improve cartilage regeneration and reduce the need for osteoarthritis treatments. The protein fragment, developed by Handan Acar and Amgad Haleem, aims to help the body heal itself by elicititing a response from stem cells.
UArizona researchers created osseosurface electronics, a wireless device that grows to the surface of bone to monitor health and healing. The thin structure allows for accurate measurements over long periods, enabling personalized orthopedic care.
Researchers from Osaka City University found that non-thermal atmospheric pressure plasma (NTAPP) accelerates cell growth and promotes bone regeneration in animal models with critical bone defects. Micro-CT images showed a 1.51 times larger bone volume after 10-minute treatment, while histological analysis confirmed new bone formation ...
A new study suggests that patient-specific plates can provide superior performance in terms of anatomical fit and fracture stability. Custom-made plates designed through computer modeling have shown potential in improving healing outcomes for clavicle fractures.
Researchers at Graz University of Technology have developed a new production method for germanium-based photoinitiators, making them cheaper and more efficient. This enables their use in contact lenses, prostheses, and artificial human tissue, among other applications.
A novel computational model predicts that articular cartilage can partially heal after injury by controlling inflammation. The study uses biomechanical and inflammatory aspects of osteoarthritis progression to develop a physics-based computational model.
Researchers at Duke University developed an antibiotic coating that can be applied to orthopedic implants before surgery, eliminating the risk of infection. The coating, made from two polymers and an antibiotic, prevents bacterial colonization and can be personalized for individual patients.
A new study suggests that same-day discharge for high-risk patients undergoing hip and knee replacement surgery is safe and feasible. The research found no increase in complications or adverse outcomes with same-day discharge compared to inpatient surgery.
The study found that robotic-aided pedicle screw placement showed accurate positioning, even for experienced surgeons, with a significant decrease in time required. The technology saved time in the operating room, making it an efficient option for spine surgery.
A multi-center study found micro-fragmented adipose tissue injections to be highly effective in reducing knee pain, improving function, and enhancing quality of life. Positive effects were observed for up to 12 months, with notable differences in efficacy among demographics.
A study developed by HSS experts shows improved patient outcomes, including reduced hospital stays and readmissions, after implementing an optimized recovery pathway for complex spine surgeries. The new approach also lowered complication rates and enabled patients to recover faster at home.
A study published in Nature Communications found that microRNA-455 helps regulate cartilage homeostasis and slows cartilage degeneration in osteoarthritis. By targeting the gene hypoxia-inducible factor-2α, miR-455 treatment inhibits cartilage breakdown.
A new study has established recognized terms, definitions, design characteristics, and prescription criteria for off-the-shelf stability footwear. This standardized approach aims to improve the effectiveness of therapeutic footwear in treating children with various mobility issues.
Researchers found that a second dose of the Pfizer vaccine, especially in those with previous SARS-CoV-2 infection, dramatically increased virus variant neutralising antibody responses. This additional boost increases potential protection against existing and future variants of concern.
The new guideline recommends invasive diagnostic tests but acknowledges their potential infeasibility, instead focusing on clinical improvement to transition to oral therapy. It provides thoughtfully reasoned recommendations based on current evidence to help clinicians identify and manage bone infections.
Research published at the American Orthopaedic Society of Sports Medicine Annual Meeting found that patients with high-grade acetabular cartilage damage have poorer outcomes after primary labral repair. The study also showed no significant difference in efficacy between chondroplasty and microfracture for patients with high-grade lesions.
A non-inferiority study found that biodegradable subacromial balloon spacers produced similar results to partial rotator cuff repairs for patients with massive rotator cuff tears at 24-month follow-up. Early improvements were noted in both groups, particularly the balloon spacer group.
Research presents alarming rate of glenohumeral arthritis progression after arthroscopic posterior stabilization in active-duty servicemembers. The study found that 12.7% of patients developed arthritis within seven years of surgery.
A study of 1,234 revision ACL reconstruction patients found that using an interference screw for femoral and tibial fixation significantly improves six-year clinical outcomes. The transtibial surgical approach also showed improved results in pain and QOL subscales.
Researchers found that quadriceps tendon autografts had a lower MRI signal at 12 months compared to hamstring tendon autografts, indicating quicker graft maturation and improved structural integrity. This suggests that quadriceps tendon autografts may have a superior rate of incorporation and synovialization.
A recent study found that 66.7% of operatively treated gymnast UCL injuries allowed return to competition at an average of 7.5 months, while 100% of non-operatively treated gymnasts RTP, with the latter group showing better scores on multiple patient-reported measures.
Despite widespread use, many common joint procedures like hip replacements and shoulder repair surgery have limited high-quality evidence to support their clinical effectiveness. The analysis highlights the urgent need for research and definitive trials to evaluate these interventions.
The Pan Am Clinic has introduced independent surgical simulation training as a requirement for residents, following research that showed improved performance and enhanced skills. The study used the ArthroS simulator to train residents, which resulted in better arthroscopic and laparoscopic skills.
A major national study is comparing the benefits of knee replacement surgery performed using a robot to a surgeon using traditional methods. The RACER study aims to determine which technique improves patient outcomes and reduces pain following surgery.
A Mount Sinai study reveals rotator cuff injuries are the most common type, accounting for nearly half of all shoulder injuries. The research also identifies other risk factors, including pitching and throwing, and highlights the need for improved injury prevention strategies.
Researchers repurpose cancer drug PLX3397 to combat sarcoma's growth and spread in animal models. The treatment inhibits CSF-1/CSF-1R signaling, reprogramming tumor-associated macrophages and stimulating immune cell infiltration.
Patients undergoing total hip arthroplasty (THA) show significant improvements in pain, function, and quality of life, as well as improved walking gait biomechanics. However, daily physical activity levels remain largely unchanged, with most patients engaging in only light physical activity.