Articles tagged with Flavonoids
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A new scientific review summarizes 12 human clinical trials on the cardiometabolic effects of wild blueberries, finding improvements in blood vessel function and beneficial changes to the gut microbiome. Regular consumption of one cup per day may support overall health benefits.
A new study from the University of Birmingham found that consuming flavanols can preserve blood vessel function in young healthy men during periods of uninterrupted sitting. The researchers tested whether high-flavanol cocoa could prevent FMD declines, and found significant protection against vascular dysfunction.
A systematic review found that higher flavonoid intakes from foods like black tea, berries, and citrus fruits are linked to a lower risk of frailty, impaired physical function, and poor mental health in older adults. Consuming more flavonoids may support healthier aging by reducing oxidative stress and inflammation.
Research suggests flavonoids improve insulin sensitivity, enhance β-cell function, modulate the gut microbiota, inhibit gluconeogenesis, and regulate enteroendocrine hormones in type 2 diabetes management. Flavonoid-specific effects on GLP-1, GIP, PYY, and CCK secretion contribute to improved glycemic control.
Researchers at Tokyo University of Science found that kaempferol increases RALDH2 levels in dendritic cells, promoting regulatory T-cell development and reducing inflammation. The study suggests that flavonoids like kaempferol may serve as natural remedies to alleviate allergic symptoms.
Researchers found that a high-flavanol cocoa drink can protect the body's vasculature against stress even after eating high-fat food. Flavanols in green tea and other foods also showed benefits for cardiovascular health.
A study has deciphered the genetic controls of flavonoids in Citrus reticulata 'Chachi', providing new insights into its flavor and health benefits. The research highlights the importance of early developmental phases in flavonoid biosynthesis, with key compounds showing significant declines as the fruit matures.
A study has discovered a protein phosphorylation mechanism that regulates flavonoid biosynthesis in tea plants under drought stress. This mechanism involves the phosphorylation of a WD40-repeat protein, leading to reduced flavonoid production.
Scientists have discovered six flavonoid 7-O-glucosyltransferase genes that play a crucial role in flavonoid glycosylation, enabling the creation of more nutritious and disease-resistant citrus varieties. This breakthrough could lead to an upgrade in citrus nutrition and health.
A new study has shown promising results for the use of enzymatically modified isoquercitrin (EMIQ) as an anti-aging ingredient in cosmetics. EMIQ was found to reduce facial trans-epidermal water loss and skin roughness, while improving skin elasticity in a 28-day clinical trial.
Researchers at Texas A&M University have found a correlation between flavonoid compounds and reduced endometriosis symptoms. Flavonoids like Quercetin and Kaempferol show promise in easing inflammation, with studies suggesting they may help suppress the symptoms of inflammatory diseases like endometriosis.
A new study by Nagoya Institute of Technology researchers reveals that the type of ceramic glaze used in tea sets can alter the retention of catechins, flavonoids with antioxidant properties. The study found that different glazes reduced the amount of beneficial compounds in tea, affecting its flavor, aroma, and potential health benefits.
A study published in the American Journal of Clinical Nutrition found that higher intake of dietary flavonols, specifically quercetin, was associated with lower odds of frailty onset. Flavonol-rich foods like apples and blackberries may be a useful strategy for preventing frailty in older adults.
Studies elucidate key aspects of traditional Chinese compounds and modern cancer therapeutics, highlighting the efficacy of R. serra in treating colitis and identifying active components of Gan Cao in treating pneumonia. A new radiolabeled antibody-based probe for detecting PD-L1 expression in cancers also provides a novel approach to ...
A daily cup of black tea could help reduce extensive abdominal aortic calcification (AAC) and lower cardiovascular risk late in life. Flavonoid intake from other sources like fruits, nuts, and dark chocolate may also offer protection.
Scientists from NUS developed a novel method for synthesizing bioactive flavonoids using molecular oxygen and alkaline water, yielding high yields of flavone dimers and oligomers with potential health benefits.
Researchers discovered that plants can regulate their microbiome through the secretion of flavonoids, which affect beneficial and harmful microorganisms around plant roots. This delicate balance helps protect plants from parasitic nematodes, reducing susceptibility to infection.
Researchers found that healthy choices, such as no smoking, high leisure-time exercise, and adequate sleep, are associated with a reduced risk of Alzheimer's disease. Additionally, intakes of certain polyphenols, commonly found in tea and other foods, may also play a role in protecting brain health among Black participants.
The Polyphenols Applications World Congress 2022 will host a cannabis symposium in Valencia, Spain, discussing recent advances on polyphenols, their applications, and innovations. The symposium aims to evaluate the constituents of cannabis and medical cannabis, mainly cannabinoids and flavonoids.
A randomized controlled trial found that consuming cranberries for 12 weeks improved participants' memory of everyday events and neural functioning. The study also showed a significant decrease in LDL or 'bad' cholesterol levels, contributing to improved vascular health and brain perfusion.
Researchers found that long-term daily cocoa consumption didn't improve exercise-induced digestive issues in male athletes. Only minor changes to their gut microbiomes were observed, indicating cocoa is not an effective exercise supplement.
Researchers from the University of Tsukuba have discovered that certain flavonoids inhibit an enzyme involved in the formation of a key insect hormone in the yellow fever mosquito. Flavonoids, found in plants and other organisms, also show larvicidal activity against mosquitoes.
Scientists found that rejuvenation treatment increases leaf biomass and flavonoid glycoside accumulation in G. biloba trees, with overexpression of GbCHS confirming its role in flavonoid biosynthesis. Gibberellins also play a significant role in stimulating tree rejuvenation.
Prunes have been found to help prevent or delay bone loss in postmenopausal women by reducing inflammation and oxidative stress. This is due to their potential to alter the gut microbiome, which can lead to lower levels of pro-inflammatory cytokines and markers of oxidative damage.
A recent study found that individuals with Parkinson's disease who consume three or more servings per week of flavonoid-rich foods like berries, red wine, and tea have a lower chance of dying during the study period. Higher flavonoid consumption is associated with better survival rates in both men and women.
A recent study found that people with Parkinson's Disease who consume more flavonoids have a lower mortality risk than those who don't. The researchers discovered that higher flavonoid intake is associated with improved survival rates in both men and women, particularly when it comes to anthocyanin-rich foods like berries and red wine.
High temperatures inhibit flavonoid accumulation in plants by suppressing the expression of flavone synthase (FNS) via the transcription factor CmMYB012. This regulates ROS production and affects plant fitness and flower color formation.
A recent study found that high temperatures inhibit the accumulation of flavonoids in plants, leading to reduced plant fitness and altered flower color formation. The researchers identified a novel transcription factor CmMYB012 as responsible for suppressing flavone biosynthesis and anthocyanin content.
Researchers from the University of Copenhagen have discovered a natural substance, a flavonoid, that can inhibit cancer cells' ability to defend themselves against chemotherapy by targeting efflux pumps. This could lead to more effective treatment and potentially even combat antibiotic resistance.
A new study published in Hypertension Journal Report found that flavonoid-rich foods, including berries and wine, can lower blood pressure by modulating the gut microbiome. The study of 904 adults suggested that increasing flavonoid intake may be a valuable strategy for preventing hypertension.
A new study found that eating a diet rich in flavonoids may lower the risk of cognitive decline. Flavonoid-rich foods like fruits, vegetables, and spices may have a protective effect on brain health.
Researchers found that plant genetic variation influences root flavonoids and soil microbial community composition, which can be impacted by frost. The study suggests that flavonoid production and interactions with microorganisms may provide tolerance to cold and frost stress in sorghum.
Researchers discovered that flavonoids from a specific corn line reduced inflammation in mice with an inflammatory-bowel-disease-like condition. The study suggests that flavonoid-rich corn may provide protective effects on human health, offering a promising new approach to treating chronic intestinal disease.
Scientists develop method to preserve beneficial properties of polyphenols and flavonoids in cancer treatment, resulting in highly effective and low-toxicity therapies.
A study of 2,800 people aged 50 and older found that low intake of flavonoid-rich foods was linked to a higher risk of developing Alzheimer's disease. Consuming more berries, apples, and tea may help prevent the condition, with even small amounts providing benefits.
Researchers discovered that plants use flavonoids to communicate with microbes in the soil, but high levels of organic carbon in the soil can repress these signals. This allows plants to control whether they invest in expensive symbionts and avoid wasting photosynthate on unnecessary microbial help.
Researchers found that moderate flavonoid consumption was associated with a lower risk of death from cancer and heart disease. Participants consuming about 500mg of total flavonoids per day had the lowest risk of a cancer or heart disease-related death, which is easily achievable through a balanced diet.
Researchers explored the cytotoxicity of glass ionomer cements with and without flavonoids on human keratinocytes. The results showed that GICs with flavonoids were less cytotoxic and had improved hardness compared to those without flavonoids.
Researchers found that flavonoids, produced by sorghum plants to defend against insect feeding, are effective in repelling corn leaf aphids. The compounds are not present in the phloem but in epidermal cells, where they can be taken up by insects and lead to their demise.
Researchers found that high flavonoid cocoa powder improved fatigue in people with multiple sclerosis by reducing mental and physical fatigue. Participants who drank the high flavonoid version showed a moderate effect on fatigability and improvements in pain symptoms, while those drinking low flavonoid cocoa saw no significant benefits.
Researchers at Salk Institute discover sterubin, a potent neuroprotective compound in Yerba santa, which may help counteract aging's effects on the brain. The study suggests that sterubin could be a promising treatment for Alzheimer's disease.
Research reveals flavonoids as potent P-gp modulators with high binding affinity and low toxicity, offering a new generation of drug candidates to reverse multidrug resistance. Synthetic flavonoid dimer FD18 specifically targets the pseudodimeric structure of the drug transporter.
Researchers at NTU Singapore have discovered a natural plant-based food preservative using flavonoids, showing strong anti-microbial and anti-oxidant properties. The organic preservative effectively kept meat and fruit juice samples fresh for two days without refrigeration.
A 15-year study found that people who eat at least one serving of oranges daily have a 60% reduced risk of developing late macular degeneration. Flavonoids in oranges appear to help prevent against the eye disease.
A study of 463 adults found that higher anthocyanin intake was associated with slower lung function decline over 10 years. Individuals in the highest quartile of anthocyanin consumption had a slower rate of decline in forced vital capacity and forced expiratory volume compared to those in the lowest quartile.
Researchers isolated two proteins from rattlesnake venom, phospholipase and crotapotin, which showed promising antiviral activity against the hepatitis C virus. These findings offer a new approach to combat this infectious disease.
A new study shows that a particular gut microbe can prevent severe flu infections in mice by breaking down flavonoids, which are commonly found in foods like black tea and blueberries. The research identifies a specific metabolite called desaminotyrosine that enhances interferon signaling, reducing lung damage from flu infection.
A six-year study found that organic onions contain more health-benefiting phytochemicals, including flavonoids like quercetin. Weather conditions were a factor in flavonoid content, but antioxidant activity was consistently higher in organic onions.
Researchers have identified flavonoids in Gymnema sylvestre R.Br. plant parts and callus culture, which exhibit antidiabetic properties. The study aimed to develop a sustainable method for metabolite production using tissue culture, helping conserve the endangered species.
Researchers at Weizmann Institute of Science found that gut microbes contribute to recurrent 'yo-yo' obesity, with a 'memory' of previous obesity retained after dieting. They developed new treatments using fecal microbiome transplantation and flavonoids, which may help alleviate the obesity epidemic.
Research has isolated tyrosinase inhibitors from diverse chemical classes in both terrestrial and marine environments. Flavonoids, terpenes, and alkaloids have been found to exhibit potent tyrosinase inhibitory activities, with potential applications in treating skin disorders and neurodegeneration.
A recent study published in The BMJ found that increased flavonoid consumption was associated with less weight gain. The largest association was seen for anthocyanins, flavonol polymers, and flavonols, with daily intake linked to a reduction of 0.16-0.23 lbs (0.07-0.10 kg) over four-year intervals.
A new study found that consuming flavonoids from anthocyanins (blueberries), flavanones (citrus fruits) and flavones (red wine) can significantly reduce the risk of erectile dysfunction, with a 14% lower risk associated with higher total fruit intake.
Brazilian researchers have demonstrated that apigenin, a flavonoid found in parsley, thyme, chamomile, and red pepper, improves neuron formation and strengthens brain cell connections. The compound works by binding to estrogen receptors, affecting the development and function of the nervous system.
Researchers found that a diet rich in plant-based flavonoids can help regulate the body's immune system response to fine particles in polluted air, potentially reducing the risk of heart disease. Additionally, a low-cost vaccine targeting PCSK9 has been shown to safely lower bad cholesterol levels in animal studies.
Tea and citrus fruits/juices associated with reduced risk of developing ovarian cancer. Flavonols/flavanones found in foods high in these compounds significantly decrease ovarian cancer risk.
A new study published by Oregon State University researchers found that a compound called xanthohumol, found in hops and beer, enhances cognitive flexibility in young mice. However, it had no effect on older mice or their learning and cognitive performance.
Researchers found that persimmon leaf flavonoid mitigates pathological injury of brain tissue following cerebral ischemia/reperfusion in rats, elevating brain ischemic tolerance. High-dose persimmon leaf flavonoid showed an identical effect to ginaton, providing a potential basis for drug development.
Researchers at the University of York found that small chemical changes to dietary flavonoids significantly impact the production of inflammatory mediators. The study demonstrates the importance of a molecule's shape in its recognition by immune cells, paving the way for designing new drugs and immunomodulators.
A University of Colorado study shows that luteolin, a common autism supplement, blocks progesterone's action but promotes estrogen-stimulated breast cancer growth. The findings highlight the need for caution when consuming flavonoid supplements, as their effects on the endocrine system are not yet fully understood.