This collection features cutting-edge supramolecular hydrogel research, including applications for antibacterial therapy and diabetic wound treatment. Versatile materials are designed for biomedical use, offering potential solutions for various medical conditions.
Researchers created a 3D platform using human-derived nerve cells and Schwann cells to study nerve cell formation and myelin coating development. The platform enables functional myelin formation and allows for the study of nerve damage and repair, as well as the testing of potential treatments.
Researchers developed a versatile hydrogel platform that enables the design of customised biomaterials for tissue engineering, disease modelling, and regenerative medicine. The platform preserves the functionality of incorporated biomolecules and supports high cell viability, enabling the creation of tissue-specific environments.
Researchers from Jilin University present a coordination–entropy regulation framework that bridges molecular solvation chemistry and macroscopic electrochemical stability. The framework delivers exceptional wide-temperature electrochemical stability, achieving ultrawide-temperature operation and high ionic conductivity.
Scientists create a new material that changes from a gel to a liquid-like state under ultraviolet light, and can be rebuilt using heat or dismantled by acid. The discovery could lead to the design of smart sensors, switchable catalysts, and materials that capture and release selected molecules on demand.
Researchers have developed a new 3D-printable cellulose hydrogel that defies freezing temperatures, maintaining ionic conductivity and mechanical strength. The hydrogel exhibits shear-thinning behavior, allowing it to flow through a 3D printer nozzle and hold its shape.
Researchers have developed a new hydrogel made from peptides that can transport ions, generate electrical signals when squeezed, or interact with cells and biological molecules. The gel has tiny water channels and is electrically polarized due to its highly organized structure made from nanofibers.
Scientists at the University of Osaka have created a new technique to build blood supply systems for artificial tissues. They successfully fabricated tubular hydrogel structures with controlled lumen sizes and complex geometries, paving the way for creating vascular models that can investigate the development of fully synthetic tissues.
Researchers developed a new formula for a hydrogel that can be printed in any shape or size, adhering to skin even when sweaty or hairy. The hydrogel also improved durability and electrical conductivity by adding graphene-based nanomaterials, making it a more potent sensor
Researchers developed an antibiotic-free multifunctional injectable hydrogel that promotes tissue repair through synergistic antioxidant and antibacterial activity. The hydrogel shows compatibility with blood and surrounding tissues, delivering therapeutic agents in a controlled and sustained manner.
A new bio-based conductive hydrogel platform is presented to preserve biomembrane activity and enable sensitive detection of organophosphate pesticides. The developed biosensor demonstrated stable operation, retaining 85.8% of its original electrochemical response after seven days.
Researchers have developed a novel hierarchical hydrogel electrolyte that balances mechanical robustness and ionic conductivity, enabling ultralong-life flexible zinc-ion batteries with impressive performance. The bioinspired design achieves exceptional ionic conductivity and accelerates Zn2+ desolvation kinetics.
Researchers developed an aerated hydrogel that allows air to pass through while maintaining its water content. This breakthrough enables longer-lasting products, such as breathable bandages, implants, and wearable sensors, with improved skin comfort and reduced sweat buildup.
A modular system designed by Worcester Polytechnic Institute Assistant Professor Jiawei Yang enables the creation of customized hydrogel implants with tailored stiffness and functionality. The system addresses critical challenges in implant design, including adhesion and immune rejection, to improve long-term performance.
Researchers introduce scaffold-microenvironment decoupling approach to construct hierarchically tough yet open polymer scaffolds with highly conductive microenvironments. The resulting hydrogel exhibits integrated properties, including high mechanical strength, ultra-high ionic conductivity, and practical efficacy in three demanding el...
Christina Tringides, an assistant professor at Rice University, has won the Pew Biomedical Scholar award to explore how glioblastoma grows and spreads into healthy tissue. Her research aims to develop personalized therapies for brain cancer by mimicking the brain's extracellular matrix.
Researchers developed a mineralized DNA hydrogel that coordinates immune regulation and sustained bone regeneration. The material promotes healing-friendly macrophage activity while supporting bone-forming stem cells, accelerating bone repair and improving tissue mineralization.
Researchers designed a biomimetic triple-network hydrogel inspired by octopus skin, combining rigid photonic ordering with soft polymer networks. The material demonstrated substantial improvements in mechanical strength and structural color response under deformation.
Researchers developed a novel smart hydrogel framework that can store multiple pages of information, revealed under different environmental conditions. The technology uses light-induced crosslinking and anti-opal structural colors to create a highly secure and aesthetically striking platform for information encryption.
Researchers design polymer networks to replicate dynamic behaviors inspired by biological systems. Self-oscillating gels exhibit rhythmic motion similar to a beating heart, while artificial photosynthetic gels convert light into chemical energy.
This innovative material combines the mechanical flexibility of an organic hydrogel with exceptional microwave absorption properties. The synergy between MXene and carbon dots provides a powerful tool for managing electromagnetic pollution in wearable electronics.
Researchers at Tampere University have developed light responsive hydrogel thin films that enable programmable surfaces with high sensitivity, rapid response, precise spatial control and reversibility. The technology opens new possibilities for tunable devices in photonics, sensing and biomedicine.
Engineers at MIT and their collaborators create a new type of soft magnetic hydrogel that can be made into complex, magnetically activated three-dimensional structures. The new gel enables the creation of microscopic, magnetically responsive robots and materials with micron-scale precision.
Researchers developed a hybrid material combining biochar with polyzwitterionic hydrogel, achieving an evaporation rate of 3.57 kg/m²/h under standard sunlight conditions. The biochar enhances light absorption, water transport, and energy efficiency, making it suitable for seawater desalination applications.
Researchers developed a novel hydrogel electrolyte that overcomes limitations of traditional hydrogels, enabling ultra-stretchability and anti-freezing capability. The material achieves high ionic conductivity and retains performance under severe deformation and extreme temperatures.
Researchers develop AIEgen-functionalized MXene nanosheets for stimuli-responsive hydrogel in pyroptosis-mediated choroidal melanoma therapy, overcoming limitations of traditional therapies. The platform achieves precise tumor discrimination and effective tumor eradication without enucleation.
New research demonstrates that restoring the physical stiffness of the gingival tissue can fundamentally change how cells respond to infection, potentially paving the way for new treatments. The study uses a hydrogel system to investigate how gum tissue stiffness impacts periodontal disease inflammation.
Researchers have developed ultra-lightweight water materials that retain water's inherent thermal advantages while overcoming its density constraints. These materials enable passive thermal management without energy-intensive active cooling systems, addressing the weight burden limitation of conventional hydrogels.
Rice bioengineer Omid Veiseh has been awarded a $2.2 million grant to develop implantable cell factory platforms that can deliver therapeutic antibodies over extended periods. The platform aims to reduce dosing frequency and improve access to biologic therapies in low- and middle-income countries.
A conductive bioglue was developed to ensure firm adhesion and stable electrical signaling within the human body. It overcomes challenges in connecting damaged tissues or attaching bioelectronic devices, promoting muscle and nerve regeneration and stable implant stability.
A novel soft biosensor with printable responsive hydrogel interfaces was developed for precise detection and differentiation of blood circulation complications in postoperative free flaps. The biosensor achieved high adhesion and high-fidelity signal acquisition while exhibiting low adhesion after monitoring to avoid wound damage.
A research team from Xi'an Jiaotong University has developed a method to align cells in muscle tissue using electric forces during electrohydrodynamic bioprinting. This breakthrough allows for the creation of living muscle tissues with tightly aligned cells, enabling the production of functional muscle constructs.
Researchers develop a multifunctional hydrogel system with broadband electromagnetic interference shielding and infrared stealth performance, exceeding that of commercial-grade materials under various harsh conditions. The gel's mechanical robustness and environmental stability are enhanced by a synergistic MXene treatment strategy.
Researchers from the University of Ottawa have developed a groundbreaking biomaterial that combines strength, adaptability, and biological compatibility for soft tissue repair. The hydrogel is made from synthetic peptides and can be precisely tailored through chemical design, making it an attractive alternative to existing biomaterials.
Researchers have developed a breakthrough light-responsive Janus dural patch using photocurable hyaluronic acid, providing strong wet adhesion and preventing unwanted tissue adhesion. The patch seals wounds within five seconds with minimal swelling and high biocompatibility.
Researchers created an ultrathin hydrogel electrode that can track vital signals without interruption, overcoming previous dehydration, freezing, and mechanical fragility issues. The new material forms a flexible layer that can withstand extreme temperatures and retain water content over time.
A novel optical microneedle device developed by researchers can quantify glucose levels in ultra-trace samples with high precision, offering a potential solution for blood-sampling-free clinical testing. The device features a functional hydrogel at its tip that reversibly binds to glucose, enabling accurate analysis without consuming t...
Researchers at PolyU have developed an acid-resistant, ultra-stable mucus-inspired hydrogel that significantly improves gastrointestinal wound healing in animals and outperforms a clinically approved mucosal protectant. The hydrogel's potential for commercialization is high due to its low cost, ease of production, and established safet...
A superhydrated zwitterionic hydrogel with dedicated water channels has been developed for nonfouling solar desalination. The hydrogel rejects ions, proteins, bacteria, and algae while allowing water to flow at a rate of 2.35 kg m-2 h-1 under sunlight.
A new composite hydrogel containing Li-Ca-Si bioceramics particles and gelatin methacryloyl matrix has shown promise in treating dental pulp infections by facilitating innervation and odontogenic differentiation. The hydrogel promoted Schwann cell regeneration, cytocompatibility for dental pulp stem cells, and proliferation of DPSCs.
Researchers developed a novel bioelectronic material that transforms from a rigid film to a soft, tissue-like interface upon hydration, enabling seamless integration with living tissues. The device, called THIN, has been shown to record biological signals with high fidelity and stability in animal experiments.
A research team at Nankai University has developed soft, stretchable 'power patches' that can be printed in various shapes and worn on the body to harvest low-grade heat. The patches generate a steady voltage when exposed to a temperature difference, making them suitable for wearable thermocells.
Christina Tringides' CHAMELEON project aims to develop soft, sensor-laden brain implants that can monitor and treat glioblastoma with greater precision. Her lab creates hydrogel-based arrays with conductive electrodes to track neural signals in real-time.
Extracellular vesicles can mediate communication between cells and tissues, influencing processes like immune signaling and cancer progression. Researchers have developed a practical, scalable EV-isolation platform that operates without preprocessing steps or specialized equipment.
Scientists at Max Planck Institute develop a novel lab-on-a-chip system using intelligent hydrogel structures to simulate spatially and temporally controlled mechanical perturbations of biological polymer networks. The system applies precise pressure forces to cellular microenvironments, enabling research into biomechanical interaction...
MIT engineers developed artificial tendons made from hydrogel to connect lab-grown muscles with robotic skeletons. The tendons improved the robot's motion and force output by three times, enabling faster and more efficient biohybrid robots.
Researchers developed a novel hydrogel that leverages radiative and evaporative cooling to efficiently manage heat in harsh outdoor environments. The breakthrough design offers enhanced fire safety and water autonomy, promising significant advancements in thermal management.
Researchers developed a composite hydrogel that integrates antibacterial, immunomodulatory, and regenerative functions to promote faster wound closure. The hydrogel demonstrated over 98% antibacterial efficacy and improved fibroblast and endothelial cell growth.
A team of researchers developed an octopus-inspired, hydraulically actuated hydrogel gripper that achieves damage-free adhesion for complex underwater manipulation. The innovative design offers a transformative blueprint for next-generation soft robotic grippers.
Researchers developed an ultra-sensitive hydrogel for human-machine interaction, achieving high-accuracy collaboration in remote surgical operations and virtual reality. The AirCell Hydrogel boasts a smooth surface and porous interior structure, allowing it to detect various human motions with exceptional accuracy.
Researchers developed an all-flexible, self-cleaning smart window that fine-tunes solar gain in real time and protects against environmental contaminants. The device's multifunctionality could accelerate green building development and address climate change concerns.
Researchers create peptide hydrogel that controls drug release, improving treatment adherence and efficacy for conditions like tuberculosis and diabetes. The SABER platform uses reversible chemical bonds to slow down drug release, offering a promising solution for precise delivery.
A new hydrogel sensor has been developed to enable long-term, high-fidelity EEG recording and attention assessment. The PGEH patch uses machine learning-powered attention decoding and reusable skin adhesion, making it a potential game-changer for wearable neuromonitoring.
Researchers developed an acid-resistant hydrogel called ultrastable mucus-inspired hydrogel (UMIH) that improved gastrointestinal wound healing in animal models and outperformed a clinically approved mucosal protectant. UMIH showed 15 times stronger adhesive abilities and remained stable for 7 days in acidic conditions.
Researchers developed a new origami-inspired folding strategy for reversible actuation of hydrogel pores, integrating facet-driven folding into polygonal pores to enable programmable and predictable actuation. This strategy retained 90% of its original shape after repeated swelling-shrinking cycles, demonstrating excellent reliability.
Researchers have developed a hydrogel electrolyte that regulates the coordination environment of water molecules, enabling high-stability and flexibility in zinc-based devices. This breakthrough can lead to advanced energy storage solutions for extreme environments.
Researchers developed a novel 3D printing technique called IPS 3DP to create personalized implants with specific mechanobiological properties. The method enables the creation of structurally complex hydrogels with hierarchical microstructures and strain-stiffening behavior, paving the way for advanced biomedical applications.
Researchers have created a wearable system that combines drug delivery, electrical stimulation, and continuous monitoring to treat diabetic foot ulcers. The microneedle platform anchors securely into the skin and adjusts therapy in real-time to prevent severe tissue damage.
Researchers have developed a smart hydrogel surface that can instantly recognize whether it's in contact with oil or water and switch its behavior to separate the two. The surface achieves a record-breaking separation speed of 17,750 liters per square meter per hour, three to five times faster than most current membranes.
Researchers have developed a self-powered microneedle patch that can monitor biomarkers without drawing blood or relying on external devices. The patch uses dermal interstitial fluid (ISF) as a cleaner sample, which contains similar biomarkers to blood and doesn't require processing before testing.