A comprehensive review in Biomedical Analysis assesses the current state and future of direct mass spectrometry for quality control, safety, and authentication of herbal medicines. The technology offers a dynamic way to ensure the safety and proper processing of potent herbal medicines by monitoring toxic compounds in real-time.
The study argues that stool data should be used to match system behavior and evaluate functional responses rather than targeting specific microbes. This approach prioritizes stability over persistence and functional outcomes over taxonomic change.
This cohort study found that TCM syndrome differentiation-based treatment improved clinical outcomes and reduced TCM symptom scores in patients with post-COVID-19 syndrome. The study showed favorable efficacy across subgroups, with a higher effective rate in the treatment group compared to the control group.
This ecological study identified hemolysis-associated disorders as major drivers of the escalating global PAH burden. Hemoglobinopathies and hemolytic anemias correlated positively with PAH incidence, with G6PD trait, other hemoglobinopathies/hemolytic anemias, and vitamin A deficiency identified as top predictors.
Chikungunya fever is caused by the Chikungunya virus, transmitted by Aedes mosquitoes. Traditional Chinese medicine offers promising integrative treatments, particularly for acute symptoms and chronic polyarthralgia. A holistic response to CHIKV requires combining standard care with evidence-based TCM.
Researchers found traditional water decoction preserves MIR2911's antiviral activity while modern manufacturing processes like ethanol-based extraction reduce it. The study suggests that process parameters can impact RNA stability and functionality.
A novel therapeutic paradigm combines electroacupuncture with regenerative tissue engineering to enhance nerve regeneration and functional recovery in spinal cord injury. The study found that electroacupuncture stimulation improved neural signal transmission, suppressed neuroinflammation, and promoted myelin regeneration.
A new study reveals that over 75% of older adults have used complementary health approaches, including mindfulness, yoga, tai chi, acupuncture, and more. The study highlights the need for healthcare providers to discuss the risks and benefits of these therapies with their patients.
Febrile neutropenia is a chemotherapy complication that Traditional Chinese Medicine (TCM) can help alleviate. TCM combines tonifying qi and blood, warming yang, and strengthening the spleen and kidney to treat FN. Combining TCM with standard therapy significantly improves outcomes.
A new study evaluates a traditional Chinese herbal formulation for diabetic kidney disease and finds it significantly improves key indicators of kidney function. The treatment modulates inflammatory pathways linked to kidney damage, suggesting a complementary strategy for preserving renal function.
A new approach integrates multimodal data, AI, and insights from traditional Chinese medicine to predict cancer risk and identify early biomarkers. This 'pan-cancer exceedingly-early' strategy offers a promising avenue for personalized early prevention.
Researchers are investigating training caregivers on ear acupressure to help alleviate chronic pain in people with dementia. The one-year initiative aims to recruit 30-40 participants, plus caregivers, and assess the feasibility and acceptability of this non-pharmacological technique.
The bioactive components of Scleromitrion diffusum exhibit potent anticancer activity by inhibiting proliferation, inducing apoptosis, and suppressing metastasis. Its multi-compound, multi-pathway approach targets several critical pathways in gastric cancer pathogenesis.
This study found that combining traditional Chinese medicine with peginterferon α-2b significantly reduces hepatitis B surface antigen, HBeAg, and HBV DNA levels. The addition of TCM also reduced myelosuppression in treatment-discontinuing patients.
A comprehensive review of 248 meta-analyses and 200 clinical trials found that most complementary and alternative medicine (CAM) treatments for autism showed weak or poor-quality evidence, making their effects unreliable. The study also highlighted the lack of safety assessments for these treatments, which can be misleading.
The Second Beijing Consensus provides a patient-centered approach to managing H. pylori-associated disease-syndrome, combining Western medical precision with TCM's holistic regulation. It recommends standard treatment regimens, including antibiotic therapy and TCM integration, as well as strategies for refractory cases.
Researchers review nanozymes derived from Chinese herbs, including their catalytic properties, biomedical applications, and potential challenges in developing herbzymes for practical use. The review highlights three main types of herbzymes: herb carbon dot enzymes, polyphenol-metal nanozymes, and herb extract nanozymes.
WANG Qi's research bridges TCM and digital technology, creating a digital constitution collection platform for objective diagnostics and a 'TCM Constitution Knowledge Graph' linking TCM with modern diseases. This work secures TCM's evolving role in contemporary healthcare through rigorous data + clinical iteration.
This study examines primary reasons for traditional Chinese medicine adoption among Chinese cancer patients and their communication with oncologists. Key findings highlight the importance of culturally sensitive care, patient education programs, and addressing misconceptions about TCM.
This review compares the bioactive components and medicinal properties of natural and cultivated O. sinensis, highlighting differences in composition and effectiveness for specific therapeutic uses. Polysaccharides, nucleosides, sterols, and amino acids contribute to their health benefits, with natural specimens often exhibiting higher...
Digital Traditional Chinese Medicine platforms are being developed to enhance perioperative care by integrating TCM's holistic principles with modern digital technologies. These platforms use AI and wearable devices to optimize the integration of TCM with ERAS protocols, providing individualized care and predictive insights into recovery.
A total of 105 compounds are identified from the SQ extract, with organic acids and amino acids dominating in the bloodstream. Pharmacokinetic profiles show dynamic changes in compound absorption and levels over time.
The study identified 105 compounds in Shenqi Fuzheng extract, with organic acids and amino acids showing higher concentrations in the bloodstream. Compounds such as Astragalosides promptly enter the bloodstream within 5 minutes after administration.
The study identified 97 potential therapeutic targets for SFJD, with 27 key targets involved in antiviral, anti-inflammatory, and immune regulation effects. Molecular docking results showed strong interactions between core active ingredients and these targets.
This review discusses the growing trend of integrating nutrients and traditional healing practices for holistic health. The authors highlight the importance of prevention, genetic and lifestyle factors, environmental and mental well-being, and the synergy between nutrients and natural medicines.
A team of scientists from NTU Singapore and HKU found that electro-acupuncture can reverse the effects of obesity in obese individuals and mice on a high fat diet. The treatment targets osteoprotegerin, a protein linked to fat cell formation and obesity development.
Researchers have identified 12 new quinoline and isoquinoline alkaloids with anti-inflammatory properties and the ability to reduce renal fibrosis in cell cultures. These findings could provide a lead for developing treatments for chronic kidney disease, according to the study published by the American Chemical Society.
A multicenter retrospective cohort study found that combining entecavir with Fuzheng Huayu reduced the cumulative incidence of hepatocellular carcinoma in patients with compensated chronic hepatitis B cirrhosis. The antifibrotic property of FZHY may be attributed to its beneficial effects on this population.
Researchers explore plant-based therapeutic compounds and traditional Chinese medicine formulas as alternatives to treat IBD, while also developing advanced diagnostic tools using metabolomics analysis. The studies found significant improvements in symptoms of IBD and treatment outcomes for chemotherapy-related toxicity.
The study assessed relationships between TCM syndromes and lung cancer TNM staging indicators, finding phlegm dampness syndrome dominant in stages I & II, Qi Yin deficiency syndrome in stages III & IV. The findings suggest bias in included literature, emphasizing the need for larger sample sizes and clinical experimental investigations.
A study published in Open Medicine found that Ginkgo Diterpene Lactone Meglumine (GDLM) improves cognitive function in patients who recently experienced an acute ischemic stroke. The treatment showed anti-inflammatory and anticoagulant effects, reducing inflammation and coagulation markers.
Tongxinluo significantly improved 30-day and 1-year clinical outcomes in STEMI patients, according to a randomized clinical trial. Further research is needed to understand its mechanism of action.
The City of Hope will lead the way in integrating complementary therapies into cancer care, supporting holistic treatment for patients. The Cherng Family Center's research and clinical programs aim to advance evidence-based standards for integrative oncology, creating an international destination for its transformational work.
Researchers have developed new methods to analyze dry-coated drug particles using 3D Raman mapping, which can effectively slow down dissolution rates. Another study introduces a novel technique for detecting complex traditional Chinese medicines, preventing adulteration and counterfeiting.
A new study calls on organizations to adopt a 'dialectic of zest' tool to destigmatize menopause and encourage women's liberation in the workplace. The research highlights the need for a holistic approach to organizational care, considering both objective and ambitious concerns of women experiencing menopause.
A multicentre prospective cohort study found that women using traditional Chinese medicine before and during pregnancy had a 2.1-times higher risk of congenital malformations compared to those without exposure. The study identified significant associations with early pregnant use and the use of two or more types of products.
Researchers found Tai Chi Chuan improved global cognition and physical markers in individuals with Type 2 diabetes and mild cognitive impairment. After 36 weeks, the Tai Chi Chuan group showed a significant average improvement of 3.29 points on the Montreal Cognitive Assessment score compared to the baseline.
A new study published in Nature Conservation found that pangolin scales are widely available in Chinese hospitals and pharmaceutical shops, despite a lack of effective regulation. The research reveals that 46% of surveyed hospitals and 34% of surveyed shops were selling pangolin scale products illegally.
Studies elucidate key aspects of traditional Chinese compounds and modern cancer therapeutics, highlighting the efficacy of R. serra in treating colitis and identifying active components of Gan Cao in treating pneumonia. A new radiolabeled antibody-based probe for detecting PD-L1 expression in cancers also provides a novel approach to ...
A new clinical trial will assess the efficacy of an AI-powered massage robot, EMMA, in managing chronic low back pain. The study aims to explore the effectiveness of robotic Tuina therapy in alleviating pain and improving health outcomes.
Researchers have identified the genetic secrets behind skullcap's anti-cancer activity, enabling the production of synthetic compounds. The discovery is expected to lead to more sustainable and rapid synthesis of cancer-fighting molecules.
Researchers uncover the origins of Kampo, tracing it back to 8th century Chinese monk Jianzhen's herbal medicines and prescriptions. These findings show that Kampo has been integrated into Japan's healthcare system for centuries, influencing traditional Japanese medicine.
Researchers from the Journal of Internal Medicine outline a strategy for analyzing traditional Chinese medicine's effectiveness against rheumatoid arthritis. The approach involves isolating active components of individual plants and testing them in animal models of the disease.
A multicenter study found that traditional Chinese medicine Yupingfeng was as effective as allopathic drugs in treating recurrent respiratory tract infections in children. The study showed a substantially greater reduction in RRTI events and similar safety profiles across all three groups.
A new study published by the American Heart Association found that sitting Tai Chi exercises improved short-term outcomes in stroke survivors with hand and arm weakness or partial paralysis. The modified sitting routine showed benefits in balance, coordination, strength, and flexibility, making it an effective option for these patients.
A new study found that traditional Chinese medicine Shengmai Yin increases the sensitivity of cancer cells to radiation, reducing radioresistance. By altering DNA methylation status, SMY enhances the efficacy of radiation therapy and reduces side effects.
Scientists have devised a method to pinpoint active ingredients from traditional Chinese medicine formulations, revealing 4 analytes with significant anti-inflammatory activity. This breakthrough could improve quality control standards and lead to better herbal remedies.
Researchers developed a novel polymeric nanoparticle that selectively binds to fibrinogen in human plasma, offering a simpler and less expensive way to manufacture fibrinogen concentrate. This breakthrough could lead to the creation of more efficient fibrinogen-specific affinity reagents for drug development.
A multi-center study assesses medicinal mushrooms and Chinese herbs for therapeutic benefit in treating acute COVID-19 infection. The MACH-19 trial evaluates the safety and feasibility of two investigational compounds, one in capsule form and another as a Chinese herbal formula.
A new study documents Nigeria's significant involvement in the transnational illegal trade of wild pangolins, with an estimated 800,000 to nearly a million animals trafficked between 2010 and 2021. The study suggests that anti-trafficking policies may be mismatched due to potential underestimation of scale.
Researchers at Shanghai Institute of Materia Medica have isolated and characterized seven novel dimeric sesquiterpenoids with potent antimalarial activities. The most potent compound, Shizukaol A, exhibits an EC50 value 1000-fold more active than artemisinin.
Recent studies demonstrate the applications of LC-MS in characterizing Traditional Chinese Medicine formulations, real-time drug measurement, and bioactive compounds from Osmanthus fragrans. These techniques offer high sensitivity, robustness, and ease of use for quality assessment and characterization.
Researchers examine the use of left atrial function indexes to evaluate left atrial function in cardiovascular disease. The study highlights their effectiveness in risk stratification and prognosis for conditions like heart failure and coronary heart disease.
Researchers from the University of Queensland are exploring traditional Chinese medicine to develop more effective strategies for conservation. The study aims to make this ancient practice more accessible and culturally nuanced for conservationists.
Researchers used network pharmacology to analyze Zhichan powder's effects on Parkinson's disease, identifying 18 major active components. This study provides new insights into the mechanism of action of Traditional Chinese Medicine prescriptions.
In China, activists are defending modern medical science and criticizing Traditional Chinese Medicine, with many using social media to spread awareness. The activists are often educated and wealthy, but still make an impact through targeted communication and direct actions.
A new reference genome of Scutellaria baicalensis reveals the genes that produce valuable compounds, enabling the development of sustainable therapeutics. The discovery could lead to rapid access to a wide range of therapeutic drugs.
Researchers have developed a new system of medical terms based on the Twenty-four Solar Terms (24-STs), allowing for more precise and location-specific treatments in Traditional Chinese Medicine. The system uses geographically dependent timings to optimize treatment effectiveness, making it a significant contribution to the field.
A review paper suggests that certain traditional Chinese medicines show benefits for cardiovascular health conditions such as hypertension and atherosclerotic cardiovascular disease. These medications have antihypertensive effects and a good safety profile, making them a potential alternative for patients intolerant of or who cannot af...
Researchers at the University of Adelaide have shown how a complex mix of plant compounds derived from ancient clinical practice in China kills cancer cells. The study characterised the molecular action of a Traditional Chinese Medicine, finding that it alters cell cycle regulation to push cancer cells down the death pathway.