Articles tagged with Asthma
The Phase 3 SUNRISE trial shows that tezepelumab nearly triples the likelihood of reducing daily oral corticosteroid dose in patients with severe, oral corticosteroid-dependent asthma. Patients treated with tezepelumab achieve greater reductions in oral steroid use while maintaining asthma control and improving key clinical outcomes.
Researchers found that a common asthma drug can help fight aggressive cancers by blocking the CysLTR1 molecule. The study used mouse models and human tissue samples to demonstrate its potential in treating triple-negative breast cancer and other tough tumors.
A major new study has found that severe asthma patients are often battling other health conditions, with nearly all suffering from at least one major issue. The study identified three distinct profiles linked to how well asthma is controlled and the treatments needed, offering potential breakthroughs for improving care.
Experts from Mount Sinai will present a new AI model that predicts lung nodule risk and assesses the impact of air pollution during pregnancy. The researchers also explore cognitive consequences of sleep-disordered breathing and reevaluate asthma guidelines to integrate both conditions.
A study led by University of Arizona researchers found that azithromycin did not improve symptoms in preschool children with severe wheezing. The trial results challenge the idea that certain types of bacteria contribute to wheezing and asthma, suggesting that viral infections play a more significant role.
A new study presents tezepelumab as a safe and effective treatment for severe asthma in underrepresented populations. The therapy reduces exacerbations by 70% and improves lung function, quality of life scores, and asthma control. It is particularly effective in patients with Type 2 asthma and those with comorbid COPD.
A new study shows that New York City's public housing mold intervention program significantly reduces asthma-related emergency department visits. The program, Mold Busters, improved ventilation and trained staff in evidence-based mold removal, leading to a 9 fewer asthma-related ED visits per thousand people.
New research from Johns Hopkins University finds that nighttime temperature swings are key predictors of asthma-related ER cases. The study suggests that updating Code Red alerts to include nighttime temperatures could help protect vulnerable communities.
The Colorado Asthma-Friendly Schools initiative recognizes 221 schools for their comprehensive asthma management and student health efforts. Over 120,000 students have benefited from the implementation of evidence-based asthma management practices at school.
A new study finds that pregnant women with low levels of a specific fatty acid molecule are more likely to have children with childhood asthma. The researchers also found that children of these mothers are more prone to respiratory infections and altered lung microbiomes.
A Swedish study found that high prenatal PFAS exposure is associated with a higher incidence of asthma in childhood. The research used a register-based cohort of children born between 2006 and 2013 to assess the relationship between maternal exposure and asthma outcomes.
A recent study found a significant link between very high PFAS exposure and an increased incidence of asthma in children. Researchers analyzed data from over 11,000 children born in Sweden and discovered that the risk of developing asthma was around 40% higher among those with very high PFAS exposure.
A long-term study found children living near the Salton Sea have slower lung function growth, with effects comparable to freeway exposure. The researchers controlled for various factors and found that dust exposure was linked to lower lung capacity, suggesting potential long-term health implications.
Researchers discovered that targeting the Dectin-1 receptor can restore functional pathways of dysfunctional immune cells like Tregs, offering a promising novel therapeutic avenue for treating allergic asthma. The study showed that this approach can reduce airway inflammation and renew immunoregulatory capacity.
A study in mice suggests that matcha may reduce the need to sneeze in people with nasal allergies, suppressing brainstem neuronal activation without changing major immune markers. The findings provide a potential, food-based option to complement standard care for allergic rhinitis symptoms.
A large survey of Texas adults with asthma found that improving airflow, using air purifiers, and minimizing allergens can significantly reduce asthma attacks. The study also highlights disparities in asthma burden among certain groups, including women, older adults, and Black adults.
New research suggests that inhaled microplastics can cause inflammation and damage to the lungs, potentially increasing the risk of respiratory diseases such as asthma and COPD. Microplastics can also trigger inflammatory responses and deliver toxins directly into the lungs, highlighting a growing concern for lung health.
A new study found that children growing up in homes with water damage and exposed to high levels of outdoor air pollution have a greater risk of developing asthma. The study also revealed that having a dog during infancy can reduce the risk of asthma in children.
A new study using satellite data confirms that California's shift to electric vehicles is making measurable differences in air quality and public health. For every 200 ZEVs added, nitrogen dioxide levels dropped 1.1%.
The American College of Chest Physicians (CHEST) received the 2025 Glenview Environmental Sustainability Award for Innovation, recognizing its commitment to clean energy and reduced emissions. The organization's solar panel installation at its headquarters powers medical simulation facilities using renewable energy.
A recent study by King's College London found that diagnosis rates for depression, asthma, and osteoporosis remained lower than expected after the COVID-19 pandemic. The study analyzed data from over 29 million people in England and found that diagnosis rates recovered differently across ethnic and socioeconomic groups.
Researchers have identified a new method to predict asthma exacerbations using sphingolipid and steroid ratios, allowing for accurate identification of high-risk patients. The method has the potential to revolutionize asthma treatment by enabling clinicians to intervene before an attack occurs.
Researchers have identified a new method to predict asthma exacerbations with a high degree of accuracy, analyzing data from three large asthma cohorts. The study found that the ratio between sphingolipids and steroids was the most powerful predictor of future health.
Adults with asthma who experience depressive symptoms have elevated blood levels of brain-derived neurotrophic factor (BDNF), a protein typically reduced in major depressive disorder. Physical activity may also play a role in depression management, as lower activity levels are linked to worse moods.
Researchers have identified a previously unknown mechanism that can reduce the risk of allergies and asthma in children. Certain bifidobacteria produce a substance called 4-hydroxyphenyl lactate (4-OH-PLA), which dampens immune responses to allergens, reducing the production of IgE antibodies.
The American College of Chest Physicians released a new clinical guideline on biologic management in severe asthma. The guideline provides evidence-based recommendations for selecting biologics for different patient populations, considering factors such as baseline oral corticosteroid use and comorbid conditions.
A recent study found that adolescents with overweight or obesity who take glucagonlike peptide-1 receptor agonists (GLP-1RA) have a lower risk of acute asthma exacerbations. This association suggests a potential dual benefit, where GLP-1RA use could address both weight management and asthma prevention in this population.
Research from University of Vermont reveals exposure to Canadian wildfire smoke worsened asthma symptoms in children in the US Northeast. The study found that smoke from hundreds of miles away affected children's health, highlighting growing health risks for the region as climate change fuels more smoke-filled summers.
Research found a heightened risk of preschool wheeze and school age asthma associated with maternal eating disorders. The study suggests including dedicated support for these disorders in maternal healthcare to improve respiratory health.
A monthly injection has helped 90% of severe asthma patients reduce their reliance on daily steroid tablets. Treatment with tezepelumab improved asthma symptoms, lung function, and overall quality of life, with two-thirds of patients experiencing no asthma attacks.
A new phase 3b clinical trial found that nearly 90% of severe asthma patients were able to reduce their steroid dose to a low dose after one year of treatment with the biologic medication Tezepelumab. The treatment also significantly improved asthma symptoms, lung function, and overall quality of life, while minimizing steroid use.
Exercise now considered a key component of asthma management, with aerobic, resistance, and flexibility training recommended. Wearable devices and home spirometry monitor lung function and exercise intensity for personalized plans.
Case Western Reserve University researchers discovered pseudo leukotrienes, which may be the dominant players in the inflammatory cascade that causes disease. The findings open new avenues for treating asthma and other inflammatory diseases.
Scientists found that breathing dusty air from the Salton Sea can alter the lung microbiome and trigger immune responses in mice. The study suggests that chronic exposure to such dust could have significant health effects, including asthma.
The analysis of 2024 English voting patterns suggests that poorer health is associated with higher proportions of votes for Reform UK. This finding highlights the need for policymakers to address health inequalities and improve public health.
The American College of Chest Physicians has designated October 19, 2025, as 'Love Your Lungs Day' in recognition of respiratory health. This initiative aims to raise awareness about lung diseases such as asthma and COPD, promoting equity and supporting healthcare providers.
Researchers developed a more accurate cough-detection model using wearable health monitors' audio and movement data. The new model can distinguish between coughs and nonverbal sounds, improving the accuracy of respiratory disease tracking.
A study of 200 classrooms found that HEPA purifiers did not significantly reduce respiratory viral exposures, suggesting additional interventions are needed. Maintaining classroom humidity between 40% and 60% may help lower viral exposures and improve comfort for students and teachers.
A recent study found no association between mould damage in schools and the development of asthma among students. Despite extensive mould damage in some schools, the health of over 30,000 students was tracked over a 16-year period, showing no increase in asthma cases.
A new study found that children who prefer pickled, smoked, and fried foods are more likely to have asthma. In contrast, seafood preference appears to reduce asthma risk among normal-weight children. The findings highlight the importance of early-life dietary habits in shaping respiratory health.
A pilot study found that hypnosis significantly improved patients' tolerance of masks, allowing them to breathe more comfortably. The study showed a substantial improvement in non-invasive ventilation (NIV) tolerance, reduced agitation, and lower requirements for sedation and anti-anxiety medication.
Research shows that remote monitoring of children's asthma can prevent hospitalizations by around 57%. The system helps keep symptoms under control, leading to better outcomes and lasting self-management skills. This innovative approach could revolutionize healthcare services for patients with asthma.
Research suggests that exposure to dog allergens in the home may reduce the risk of developing childhood asthma by five years old. Babies with higher levels of Can f1, a dog skin protein, had around a 48% lower risk of developing asthma and better lung function.
Researchers developed AI tools that use machine learning and natural language processing to extract details from doctors' notes. The tools detected a high-risk asthma subtype that makes some children more vulnerable to acute respiratory infections and asthma exacerbation.
A review of hundreds of studies found a link between childhood plastic exposure and long-term health concerns like heart disease, obesity, and asthma. Parents can take simple steps to limit their children's plastic exposure, such as replacing plastic containers with glass or stainless steel.
A new study found that inhaling marijuana daily is associated with a 44% increased chance of developing asthma. Experts say people should avoid inhaling cannabis to reduce the risk of chronic lung disease. The study's authors emphasize the need for clearer messages about the risks of cannabis use.
A study led by Harvard T.H. Chan School of Public Health found that long-term exposure to fine particulate air pollution (PM2.5) from metals like nickel and vanadium, and sulfate particles, is strongly linked to asthma hospitalizations. The researchers identified these compounds as the most harmful components in the PM2.5 mixture.
Researchers at Children's Hospital of Philadelphia found that certain lipids in obesity-causing foods cause asthma-like lung inflammation. The study suggests that modifying dietary choices and repurposing existing drugs could help treat this type of asthma, which is more likely to send patients to the hospital.
A review of systematic reviews finds a consistent association between youth vaping and subsequent smoking, marijuana, and alcohol use. Vaping is also linked to various respiratory and mental health issues, including asthma, pneumonia, bronchitis, and suicidal outcomes.
A comprehensive epidemiological study found that people who had COVID-19 are at increased risk of developing certain inflammatory diseases of the airways, such as asthma and chronic sinusitis. Vaccination against SARS-CoV-2 virus appears to reduce this risk.
A recent study reveals three distinct inflammatory drivers of asthma exacerbations in children, including epithelial pathways, macrophage-driven inflammation, and mucus hypersecretion. These findings suggest that targeted therapies may not be enough to prevent flare-ups, emphasizing the need for more personalized treatment approaches.
Conventional dendritic cells have been found to originate from both myeloid and lymphoid progenitors, revealing their unique functions and developmental pathways. These lymphoid-derived cDCs exhibit potent functions in immune suppression and allergy induction, and follow diverse developmental pathways.
Researchers have engineered a monoclonal antibody that blocks allergic reactions against common pollen when applied inside the nose of mice, providing new hope for hay fever sufferers. The treatment, known as a 'molecular shield,' acts immediately and locally at the lining of the nose to prevent IgE antibodies from being activated.
A study using AI language models analyzed sentiments and emotions expressed by almost 400 pediatric patients on social media, finding that 94% of comments were negative, with sadness and fear prevalent. The study highlights the need for integrated care approaches to support vulnerable young patients managing complex medical conditions.
A new study from Karolinska Institutet found that biological drugs used to treat severe asthma do not completely eradicate inflammatory cells. Researchers discovered an increase in blood levels of these cells during treatment, which could explain why inflammation often returns when treatment is tapered or discontinued. The study aims t...
Researchers at IU School of Medicine have developed a new digital marker to predict asthma diagnoses in children using electronic health records. The passive digital marker is more accurate than traditional methods and can be used to enhance early detection rates, reducing the risk of asthma progression in young patients.
Researchers used geospatial neighborhood and housing data to predict lung function among children with asthma living in homes with more roaches and rodents. The study highlights the impact of environmental exposures on asthma health disparities among Black and Latino children.
Researchers found that ibudilast works better for women who have lower levels of depression and inflammation. The study, which recruited 102 adults with moderate or severe alcohol use disorder, showed that ibudilast did not reduce drinking in most participants, but had a positive effect on female participants.
Researchers will present AI models that predict chronic respiratory failure and detect airway obstruction, with key findings on asthma susceptibility, small airway disease, and lung inflammation. The studies use nasal epithelial gene expression analyses and bronchoscopy to identify potential biomarkers for ICU patient outcomes.