A new study suggests that women vaccinated against human papillomavirus (HPV) may only need cervical cancer screenings 2-3 times over a lifetime, without compromising health benefits. This approach could lead to cost-effectiveness and reduced unnecessary follow-up procedures.
Researchers developed an AI tool called ONCO-ACS to predict the risk of secondary heart attacks in cancer patients after a heart attack. The tool combines cancer-related factors with standard clinical data to provide reliable information for doctors to balance treatment benefits and harms.
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According to a new study, Massachusetts is close to eliminating cervical cancer due to its low incidence rate of 4.3 cases per 100,000 in recent years. In contrast, the Southeast and Southwest regions have higher rates of 11.2 and 9.9 cases per 100,000, respectively, making it challenging for these states to reach elimination goals.
The American Cancer Society's new 'Cancer Statistics, 2026' report reveals a historic milestone: US cancer survivorship has reached a record 70%, driven by major gains in cancers once considered difficult to treat. However, the report also highlights persistent disparities, concerning increases in cancer among women and younger adults.
The Global Centre for Asian Women’s Health has partnered with NUS Medicine to host the Women’s Health Impact Tracking (WHIT) platform, which measures progress on closing the women’s health gap across a set of conditions and countries. The platform provides clear, comparative insights to support decision-making and inform policies.
The new guidelines update past recommendations to focus on 30-year-old women with risk factors, while simplifying screening for younger and older populations. The changes aim to reduce overtreatment and improve health outcomes for cervical cancer patients.
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A study published in JAMA Network Open reveals low adherence to cervical cancer screening guidelines among commercially insured US adults, with only 7.3% following recommended guidelines. The findings suggest that guideline confusion and lack of incentives are contributing factors to this issue.
A case report describes a woman with radiation-induced cellular changes in her Pap smear that mimicked cancer recurrence. The study emphasizes the importance of recognizing these changes to prevent misdiagnosis and unnecessary medical procedures.
Two new Cochrane reviews show that HPV vaccines are effective in preventing cervical cancer and pre-cancerous changes, especially when given to young people before they are exposed to the virus. Girls vaccinated before the age of 16 were found to be 80% less likely to develop cervical cancer.
A new study using magnetoelectric nanoparticles successfully shrinks pancreatic tumors in preclinical models, extending survival. The Sylvester Cancer Institute has also launched its Survivorship and Supportive Care Institute to provide evidence-based care for cancer patients.
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Researchers at Chiba University have developed a nasal therapeutic vaccine targeting E7 oncoprotein, which is produced by high-risk strains of HPV associated with cervical cancer. The vaccine triggers an immune response in the cervical mucosa, providing local protection against pathogens and foreign particles.
A study published in Chinese Medical Journal identified tumor-promoting keratinocytes linked to HPV infection and poor prognosis. These cells were found to interact with immune cells, promoting tumor proliferation and differentiation.
A new AI-driven platform, Intelligent Digital Education Tool for Colposcopy (iDECO), has been developed to bridge training gaps in cervical cancer prevention. The platform uses real clinical cases, gamified learning, and personalized analytics to enhance diagnostic accuracy and decision-making among medical professionals.
A new study found that adding chemotherapy to radiation therapy causes a greater decline in quality of life for women with early-stage cervical cancer. The trial measured patient-reported outcomes, including symptoms and side effects, highlighting the need for supportive care during treatment.
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A major study of breast, cervical, and ovarian cancers found significant inequalities in global care, with many low- and middle-income countries (LMICs) diagnosing cancer at a later stage. Surgery was offered consistently, but treatment consistency varied, with LMICs often choosing mastectomy over breast-conserving surgery.
The study reveals geographic clusters of high and low screening for breast, cervical, and colorectal cancers in the US Northeast and Southwest. Future studies could examine county-level healthcare access to optimize cancer screening practices.
Chinese researchers contribute to global cervical cancer prevention with affordable HPV vaccines, self-sampling methods, triaging strategies, and AI-assisted screening. These innovations offer scalable solutions to accelerate progress toward eliminating cervical cancer worldwide.
Researchers tested an AI-supported diagnostic method at rural hospitals in Kenya and Tanzania, analyzing cervical cell samples and human papilloma virus (HPV) samples using digital tools. The study found that the AI method worked well technically but faced challenges with inconsistent images and follow-up care.
The ASPIRE trial is a Phase III clinical study investigating whether adding chemotherapy to standard treatments can extend survival in men with advanced prostate cancer. The trial aims to determine the effectiveness of combining docetaxel with hormone therapy and apalutamide.
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Researchers at Aarhus University used mini-organs to show that cervical epithelial cells actively detect and combat infections, with uninfected cells becoming immune-active. This discovery opens opportunities for mucosal vaccines and targeted treatments against STIs and infertility.
A new study by Kaiser Permanente found that mailing human papillomavirus (HPV) self-sampling kits to patients increases cervical cancer screening completion rates. The study also shows that this approach is cost-effective, especially for health systems with a wide range of patient populations.
A large study found the HPV vaccine to be highly effective in protecting young women from infections caused by the virus, including those who didn't receive the vaccine. The research also showed clear evidence of herd immunity, suggesting that widespread vaccination can indirectly protect unvaccinated individuals.
A new study finds that women who have overcome cervical cancer are nearly twice as likely to develop anal cancer compared to the general population. The study highlights the need for updated screening guidelines for these patients.
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A cross-sectional study found that the bivalent HPV vaccine induces sustained immunity in Bangladeshi adolescent girls, with significant associations between HPV16/18 seropositivity and age, grade level, and household income. The overall seroprevalence was high, with 72.8% for HPV16 and 82.4% for HPV18.
The study found that EBV nuclear antigen 1 (EBNA1) significantly increases the expression of Derlin1 and PSMD10 genes in HeLa cells, both associated with enhanced cancer cell survival and proliferation. This suggests a potential mechanism by which EBV may contribute to cervical cancer progression.
Researchers found that HPV16 undermines the body's defenses by reprogramming immune cells surrounding tumors. Blocking IL-23 boosts experimental treatments for HPV to eliminate cancer cells.
Scientists have developed a monoclonal antibody to combat life-threatening inflammatory diseases like sepsis and ARDS. The antibody shows promise in blocking the immune system's hyperactive response and restoring healthy function without unwanted side effects.
New research reveals that most people are unaware of the link between human papillomavirus (HPV) and various types of cancer, including cervical, oropharyngeal, anal, vaginal, vulvar, and penile cancers. The study highlights the importance of HPV vaccination in preventing these cancers.
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This study found a nearly two-fold higher cervical cancer incidence in counties with repeatedly low vs high cervical cancer screening coverage. The disparity was most pronounced in rural counties with lower income levels.
Women in counties with low cervical cancer screening rates experience nearly double the rate of cervical cancer diagnoses, particularly late-stage disease, and death. Timely screening can identify precancerous lesions for removal before they develop into cancer.
A new study suggests that offering self-collection kits during routine GP appointments can increase participation rates among women overdue for cervical screening. The approach shows promise in reducing the number of cases and saving lives.
A Danish study finds that HPV vaccination has reduced prevalence of high-risk HPV types among vaccinated women, suggesting population immunity. However, non-vaccine types remain common and new infections occur more frequently in vaccinated women than unvaccinated women.
A large observational study found that women over 65 are at higher risk of cervical cancer due to HPV, contradicting current guidelines. The study suggests that these women should be re screened for cervical cancer as the risk is significantly higher than previously thought
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Researchers found that it took 13 years for cervical cancer screenings to halve among women over 65, and even longer for prostate cancer screenings to decrease significantly. The study emphasizes the need for more effective tracking mechanisms to identify and reduce inappropriate screening practices.
The ESMO Gynaecological Cancers Congress 2025 will convene in Vienna, Austria, from June 19-21, featuring novel data on immunotherapy combinations and emerging treatment strategies for rare gynaecological cancers. The congress will also explore innovative approaches using antibody-drug conjugates.
Researchers validate new at-home cervical cancer screening device, the Teal Wand, as a safe and effective alternative to traditional in-clinic screenings. The device detects precancer 96% of the time, detecting HPV-related cells that may develop into cancer.
A cohort study found that long-term survival was similar among patients with low-risk early-stage cervical carcinoma who underwent simple, modified, or radical hysterectomy. These findings support the use of simple hysterectomy in select patients.
Researchers discuss innovative approaches to improve quality of life for cervical cancer patients, exploring phytocannabinoids, anti-angiogenic drugs and peptide-based therapies. These strategies aim to reduce opioid side effects and target tumour growth and progression.
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Two new predictive algorithms use health data and blood tests to identify high-risk patients, offering improved accuracy in diagnosing cancers. The models identified additional medical conditions associated with increased cancer risk and new symptoms indicative of multiple cancer types.
Researchers from the University of Southampton engineered a new type of super-strong antibody that triggers a stronger response from the immune system compared to naturally produced antibodies. The study confirms that making subtle increases in rigidity stimulates immune activity, creating a powerful immune response against disease.
Hyperbaric oxygen treatment has been shown to provide long-term relief for patients with late radiation-induced injuries, improving symptoms of urinary incontinence, bleeding, and severe pain. The treatment can lead to the healing of chronic injuries and allow patients to live a fully normal life.
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The latest ACS cancer prevention and early detection report reveals mixed progress in major cancer risk factors, preventive behaviors, and screenings among US adults. Smoking rates have continued to decrease, while breast and colorectal cancer screening have rebounded, but cervical cancer prevention remains a concern.
Cervical cancer cases worldwide reached 622,301 in 2022, with significant variations in age-standardized incidence rates across regions. Targeted prevention programs, especially HPV vaccination in low-income countries, are essential to reduce the global health burden.
Researchers found that Schistosoma haematobium parasitic infection triggers cancer-related gene activity in cervical lining, with treatment causing further changes. This study sheds light on how the parasite may contribute to cervical cancer risk at a molecular level.
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Researchers at MD Anderson Cancer Center made several key discoveries, including the spatial organization of cancer-associated fibroblasts across various cancers and a study on treatment resistance in SMARCA4-mutant lung cancer. These findings highlight the importance of investigating cell populations in their spatial context to better...
The national healthcare initiative has been extended for five years to provide world-class healthcare services to every Guyanese citizen. The partnership will establish a national cancer center, modernize national health facilities, and implement an advanced digital health system.
A team led by Professor Jeong Youngtae has discovered the identity and differentiation process of human cervical stem cells using organoid models. Lactic acid bacteria were found to inhibit the development of cervical cancer by secreting lactic acid that impedes the effects of the human papillomavirus.
The NRG Oncology GOG-0263 phase III clinical trial found that adding cisplatin-based chemotherapy to adjuvant radiotherapy following radical hysterectomy did not improve outcomes and led to increased toxicity. Radiotherapy alone remains the standard of care for early-stage, intermediate-risk cervical cancer.
Researchers found that women who received text message reminders were twice as likely to get their cervical cancer screenings within 150 days compared to those without reminders. The study suggests a promising low-cost approach to increasing cancer screenings in underserved populations.
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Breast and colorectal cancer screening rates have recovered from pandemic-related declines, surpassing pre-pandemic estimates. Cervical cancer screening rates remain below pre-pandemic levels, indicating a persistent trend of declining early-stage diagnoses.
A survey reveals that most people are unaware of HPV's impact on cancer risk and its spread. The human papillomavirus (HPV) is more common among men than women, and the virus is associated with rising rates of oropharyngeal cancers, which can take years to develop after initial infection.
Cervical cancer incidence increased in rural US counties, with higher rates among white women, likely due to lower screening coverage and diagnostic care utilization. Rural areas may experience heightened access barriers, contributing to lower HPV vaccine uptake.
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Researchers at MD Anderson Cancer Center have identified biomarkers for predicting treatment response in metastatic breast cancer and found a potential target for tumor progression in pancreatic cancer. Additionally, they discovered that abnormal chromosome changes predict survival in patients with secondary acute myeloid leukemia.
US researchers found that self-sampling using vaginal swabs is as effective as speculum-based testing for detecting high-risk HPV types. The study suggests that self-sampling could reduce the incidence of cervical cancer in women with physical disabilities, who often face barriers to traditional screening methods.
A large study found pregnant women with cervical cancer face higher health risks during pregnancy and childbirth, including premature birth and cesarean sections. However, the babies' health is largely unaffected, with no significant differences in birth defects or stillbirths.
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A new longitudinal study has provided unprecedented insights into human papillomavirus (HPV) infection dynamics. The study found that non-persistent infections exhibit a plateau in viral load before rapidly declining, while chronic infections show a strong correlation between immune cells and virus production. This research could infor...
BGI Genomics has launched a National Cervical Cancer Prevention and Control Program in Brunei, utilizing HPV DNA testing for large-scale screening. The initiative aims to increase accurate and reliable early detection methods, aligning with the WHO's global strategy of cervical cancer elimination by 2030.
Researchers found that protective Lactobacillus microorganisms were present at lower rates in Native American women compared to non-Native women. This disruption in the vaginal microbiome increased the risk of human papillomavirus infection, leading to higher cervical cancer rates among Native American women.
A new study from Karolinska Institutet and Queen Mary University of London has developed a method to divide HPV-positive women into three risk groups, based on the variant of the HPV virus and the amount of virus present in the self-test. This method could enhance cervical cancer screening for high-risk women.
The study found that early initiation of the HPV vaccine series led to significant improvements in vaccination rates across all racial and ethnic groups. Vaccination rates increased from 13.2% in 2019 to 42.2% in 2022, with notable increases for Hispanic or Latino, Black, Asian, and white patients.
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