Scientists create hybrid composite scaffolds with aligned nanofibrous architectures to improve cell seeding efficiency, proliferation rates, and morphogenesis. The findings have potential applications in tissue repairing and regenerative medicine.
SourceInternational Journal of Extreme Manufacturing·JournalInternational Journal of Extreme Manufacturing·DateMar 14, 2023
A new coating material developed by Korean researchers facilitates bone regeneration and attracts osteo-progenitor cells, significantly improving the success rate of dental implants. The coating, loaded with BMP-2, prevents non-osteogenic cell invasion and induces high bone differentiation in a short period.
SourcePohang University of Science & Technology (POSTECH)·JournalBioengineering & Translational Medicine·DateMar 13, 2023
Davis Instruments Vantage Pro2 Weather Station
Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.
Researchers at Hokkaido University used hydrogel materials in combination with neural stem cells to grow new brain tissue in areas of brain damage. The study showed that immune cells and blood vessels grew within the hydrogels, leading to some degree of integration between the hydrogel and host brain tissue.
SourceHokkaido University·JournalScientific Reports·TypeExperimental study·DateFeb 23, 2023
Researchers at Northwestern University developed a first-of-its-kind small, flexible, stretchable bandage that accelerates healing by delivering electrotherapy directly to the wound site. The bandage healed diabetic ulcers 30% faster than in mice without the bandage.
SourceNorthwestern University·JournalScience Advances·TypeExperimental study·DateFeb 22, 2023
Researchers found that platelet depletion increased amyloid plaque size and neuronal damage in APP-PS1 mice. However, platelets may have a beneficial role in limiting plaque growth and attenuating neuritic dystrophy at advanced stages of Alzheimer's disease.
SourceImpact Journals LLC·JournalAging-US·TypeExperimental study·DateFeb 15, 2023
Researchers at MLU and partners developed a new process coating implant materials with a gene-activated biomaterial that induces stem cells to produce bone tissue. This method, published in Advanced Healthcare Materials, stimulates bone healing in a targeted manner with fewer side effects than existing methods.
SourceMartin-Luther-Universität Halle-Wittenberg·JournalAdvanced Healthcare Materials·TypeExperimental study·DateFeb 9, 2023
Researchers at Rice University have developed a self-assembling peptide ink that enables the 3D printing of complex structures with cells, which can then be used to grow mature tissue in a petri dish. The ink allows for control over cell behavior using structural and chemical complexity.
SourceRice University·JournalAdvanced Materials·TypeExperimental study·DateFeb 7, 2023
Rigol DP832 Triple-Output Bench Power Supply
Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.
Researchers developed an injectable biomimetic hydrogel composite loaded with stem cells that promotes regenerative healing in animal models of Crohn's perianal fistulas. The treatment reduced fistula size by six-fold compared to surgery, offering a potential new paradigm for treating this condition.
SourceJohns Hopkins Medicine·JournalScience Advances·DateJan 25, 2023
Collagen deposition at injured sites in the gut stimulates cellular reprogramming, converting mature cells into fetal-like cells to generate new tissue. This process has implications for understanding intestinal inflammation and potentially colorectal carcinogenesis.
SourceTokyo Medical and Dental University·JournalInflammation and Regeneration·DateJan 6, 2023
Researchers discovered that damaged cells and aging induce high levels of oxidative stress and DNA damage in a subset of cells, leading to senescence. Senescent cells repress muscle regeneration by releasing inflammatory factors, while also promoting fibrosis, highlighting the need to remove these cells for improved repair.
SourceUniversity of Luxembourg·JournalNature·TypeExperimental study·DateDec 21, 2022
The research team successfully transplanted a stem cell sheet onto the heart, promoting angiogenesis and improving cardiac function. The technique has improved integration and engraftment rates, addressing challenges in patch-based treatments for myocardial infarction.
SourcePohang University of Science & Technology (POSTECH)·JournalBiofabrication·DateDec 16, 2022
Sony Alpha a7 IV (Body Only)
Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.
Scientists at Duke University have made a breakthrough in controlling gene expression in response to injury, using a segment of fish DNA called TREE. The method successfully targeted gene activity to specific regions and time windows, showing promise for regenerating damaged tissues in mammals.
SourceDuke University·JournalCell Stem Cell·TypeExperimental study·DateDec 13, 2022
Researchers at Indiana University School of Medicine developed a minimally invasive nanochip device that can reprogram tissue function by delivering specific genes. The technology has shown promise as a treatment for traumatic muscle loss, with improved muscle function observed in rats following volumetric muscle loss.
SourceIndiana University·Journalnpj Regenerative Medicine·TypeExperimental study·DateNov 9, 2022
Researchers have discovered a way to reactivate a fetal repair pathway in adults to improve healing of diabetic wounds. The study used tissue nanotransfection technology to deliver a gene that activates the protein NPGPx, which is active in fetuses but largely inactive in adults and absent in diabetic adults.
SourceIndiana University School of Medicine·JournalMolecular Therapy·DateNov 2, 2022
The Vilcek Foundation has awarded $250,000 in prizes to four leading immigrant scientists: Alejandro Sánchez Alvarado, Edward Chouchani, Biyu J. He, and Shixin Liu. They received the 2023 Vilcek Foundation Prizes in Biomedical Science for their groundbreaking work in regeneration, metabolic disease, cognitive neuroscience, and nanoscal...
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
Researchers at CNIO have identified alveolar type II pneumocytes as the primary cell type responsible for developing pulmonary fibrosis. The study reveals that targeting these cells through telomere-based therapy may lead to a breakthrough in treating this debilitating disease.
SourceCentro Nacional de Investigaciones Oncológicas (CNIO)·JournalNature Communications·TypeExperimental study·DateOct 6, 2022
A study from University of California, Davis, and Harvard Medical School reveals multiple new sirtuins in early branching animals like jellyfish, sea sponges, and sea anemones. These proteins are involved in metabolism and DNA repair, playing a crucial role in the unique longevity strategies of these animals.
SourceUniversity of California - Davis·JournalMolecular Biology and Evolution·TypeExperimental study·DateSep 22, 2022
Stowers scientists investigate macrophage activation states in zebrafish sensory organ, discovering three distinct anti-inflammatory pathways that may inform human regenerative immunotherapies. The study provides valuable insights into the timing and genetic programs of macrophages, a type of white blood cell, in repair and regeneration.
SourceStowers Institute for Medical Research·JournalNature Communications·TypeExperimental study·DateSep 20, 2022
Researchers have discovered a cellular and molecular mechanism essential for intestinal epithelial regeneration. Progenitor cells modulate the production of mitogenic factors, controlling intestinal stem cell proliferation and tissue regeneration. This finding breaks new ground in research into counteracting radiotherapy side effects.
SourceCentro Nacional de Investigaciones Oncológicas (CNIO)·JournalJournal of Experimental Medicine·TypeExperimental study·DateSep 14, 2022
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
Researchers studied axolotls to understand brain regeneration, finding similarities between development and regeneration processes. They discovered a rejuvenated state of development during regeneration, which could lead to improved treatments for severe injuries in humans.
SourceBGI Genomics·JournalScience·TypeImaging analysis·DateSep 6, 2022
A study published in Cell Stem Cell found that mitochondrial dynamics regulate the dormant state of adult muscle stem cells, which are essential for tissue stability. The researchers discovered that the protein OPA1 regulates this process and its depletion leads to severe muscle stem cell defects.
SourceUniversity of Ottawa·JournalCell Stem Cell·DateSep 2, 2022
A study by HKU Dentistry found that 'positive stress' can induce good changes in tooth stem cells, making them more resistant to injury and disease. The research team developed a preconditioning protocol that modified the cells genetically to mimic low oxygen conditions, which activated protective mechanisms.
SourceThe University of Hong Kong·JournalJournal of Dental Research·TypeExperimental study·DateAug 31, 2022
A recent study by Medical University of Vienna researchers has identified a crucial dual function of neutrophils in liver regeneration after partial hepatectomy. The findings suggest that these immune cells produce factors necessary for liver growth, enabling the organ to recover quickly from tissue damage.
SourceMedical University of Vienna·JournalJournal of Hepatology·DateAug 24, 2022
Sky-Watcher EQ6-R Pro Equatorial Mount
Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.
Researchers discovered an evolutionarily-conserved genomic region that regulates Wingless protein expression during wing formation and regeneration. This region also ensures proper wing development, but chronic activation leads to tumour growth.
SourceInstitute for Research in Biomedicine (IRB Barcelona)·JournalNature Communications·DateAug 22, 2022
Researchers at RIKEN have discovered how marsupials' hearts can regenerate for several weeks after birth, allowing for potential treatment of human heart disease. They found that inhibiting a protein called AMPK extended the period of regeneration in both mice and opossums, with minimal scarring.
Penn State researchers are developing a biodegradable nerve scaffold that employs folate and citrate to promote tissue regeneration and Schwann cell migration, which is critical for nerve growth and repair. The team aims to use this scaffold to encourage nerve regeneration by delivering a significant concentration of folate locally.
Scientists have identified a critical source of essential molecules that enables the intestine's self-renewal and regeneration after injury. The study reveals that lymphatic endothelial cells play a key role in maintaining stem cell activity and tissues in the intestine.
SourceCedars-Sinai Medical Center·JournalCell Stem Cell·DateAug 4, 2022
Researchers at Max Delbrück Center for Molecular Medicine found that zebrafish can regenerate heart tissue after injury due to activated fibroblasts. The fibroblasts, which temporarily enter an activated state, read a series of genes responsible for forming proteins, enabling the regeneration process.
SourceMax Delbrück Center for Molecular Medicine in the Helmholtz Association·JournalNature Genetics·TypeExperimental study·DateJul 21, 2022
Meta Quest 3 512GB
Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
Researchers at Indiana University School of Medicine used tissue nanotransfection (TNT) technology to edit genes in chronic wound tissue, rescuing wound healing. The study found that gene silencing due to DNA methylation was a critical barrier to wound closure.
SourceIndiana University School of Medicine·JournalJournal of Clinical Investigation·DateJul 18, 2022
Biomedical engineers have created a novel 3D synthetic structure that mimics the extracellular matrix, guiding neural progenitor cells and promoting their differentiation. The results show promise for developing brain-healing treatments, including biogels that can repair and regrow brain tissue after a stroke or other trauma.
SourceDuke University·JournalAdvanced Materials·TypeExperimental study·DateJul 15, 2022
The 13th Annual Meeting on Skin Challenges 2022 will discuss recent advances in skin ageing, focusing on extracellular vesicles and their therapeutic potential. Experts will also share findings on the skin microbiome and its role in age-related diseases.
SourceMitochondria-Microbiota Task Force·DateJul 6, 2022
Garmin GPSMAP 67i with inReach
Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.
Researchers at Texas A&M University have challenged the common belief that nerves are necessary for limb regeneration in mammals. Their studies, published in the Journal of Bone and Mineral Research and Developmental Biology, found that mechanical loading is a critical component for mammalian regeneration.
SourceTexas A&M University·JournalDevelopmental Biology·TypeNews article·DateJul 5, 2022
A KAUST-developed nanotechnology platform uses tiny iron wires that bend in response to magnetic fields to accelerate bone cell formation. Bone-forming stem cells grown on the moving substrate transform into mature bone much faster than usual, potentially paving the way for more efficient regeneration of bone.
SourceKing Abdullah University of Science & Technology (KAUST)·JournalJournal of Nanobiotechnology·DateJul 3, 2022
Researchers have devised a way to deliver carbon monoxide to the body using stable foams that can be delivered to the digestive tract. The foams reduced inflammation of the colon and helped reverse acute liver failure in mice, offering a potential alternative to immunosuppressive treatments.
SourceMassachusetts Institute of Technology·JournalScience Translational Medicine·DateJun 29, 2022
Researchers identified glucocorticoids as a key factor inhibiting cardiac regenerative capacity after heart attacks. The study showed that deleting or blocking the glucocorticoid receptor increased heart muscle cell replication and regeneration.
SourceUniversità di Bologna·JournalNature Cardiovascular Research·DateJun 29, 2022
Apple MacBook Pro 14-inch (M4 Pro)
Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
Researchers have discovered that human urine-derived stem cells have the ability to regenerate tissue and become various cell types, making them a promising source for stem cell therapy. The study also highlights the importance of telomerase activity in maintaining regenerative potential.
SourceAtrium Health Wake Forest Baptist·JournalFrontiers in Cell and Developmental Biology·TypeExperimental study·DateJun 28, 2022
Researchers at MIT have created a new liver tissue model that identifies one molecule playing a key role in human liver regeneration. The study also reveals several other candidates that will be explored further to discover new human-specific pathways.
SourceMassachusetts Institute of Technology·JournalProceedings of the National Academy of Sciences·DateJun 27, 2022
Researchers discovered increased cell cycle activity and proliferation in cardiomyocytes after heart surgery, allowing for remuscularization of the left ventricle. The study identified key genes involved in pathways regulating heart development and cell proliferation.
SourceUniversity of Alabama at Birmingham·JournalCirculation·TypeExperimental study·DateJun 24, 2022
GoPro HERO13 Black
GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.
Researchers at the Salk Institute have identified an unexpected molecular target of a common treatment for alopecia, a condition where the immune system attacks hair follicles. They found that glucocorticoid hormones instruct regulatory T cells to activate hair follicle stem cells, leading to hair growth and regeneration.
SourceSalk Institute·JournalNature Immunology·DateJun 23, 2022
A team of scientists has developed a complex tissue platform that can restore damaged rotator cuffs through 3D-bioprinting. The platform, which includes stem cells and tissue-specific extracellular matrix bioink, regenerates tissues and improves shoulder function in animal models.
SourcePohang University of Science & Technology (POSTECH)·JournalBioactive Materials·DateJun 21, 2022
Researchers found that tenascin C and tenascin R impede the regeneration of myelin sheaths in mice with multiple sclerosis. Mice lacking these proteins rebuilt their myelin sheaths faster and more effectively.
Apple Watch Series 11 (GPS, 46mm)
Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
Researchers at Champalimaud Centre found that Wg/Wnt signaling molecule helps mount a regenerative response to brain damage. Neurons sense tissue distress, triggering dormant neural stem cells to activate and produce new neurons.
SourceChampalimaud Centre for the Unknown·JournalDevelopmental Cell·TypeExperimental study·DateJun 17, 2022
Researchers identified immune endothelial cells promoting inflammation and developmental endothelial cells supporting cell development, regeneration, and proliferation. The study's findings may lead to targeted treatments for lung infections and acute respiratory distress syndrome.
SourceUniversity of Illinois Chicago·TypeExperimental study·DateJun 14, 2022
A NJIT-led team has created an injectable hydrogel designed to recruit dental pulp stem cells and promote tissue growth in teeth after a root canal. The therapy mimics the body's natural growth factor signaling, promoting healing and regeneration of lost tooth pulp.
SourceNew Jersey Institute of Technology·DateJun 9, 2022
A new platform mimics live cellular environment to guide stem cell differentiation outside the body. Researchers from Chung-Ang University developed a novel platform based on metal-organic frameworks, which offers advantages over conventional methods for in vitro stem cell differentiation.
SourceChung Ang University·JournalScience Advances·TypeExperimental study·DateJun 9, 2022
Nikon Monarch 5 8x42 Binoculars
Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.
Researchers at Cedars-Sinai have discovered that zinc, a common mineral, plays an important role in reversing lung damage and improving survival for patients with idiopathic pulmonary fibrosis (IPF). By identifying a molecular pathway involving zinc, the team hopes to develop new therapies to reverse IPF-related lung damage.
SourceCedars-Sinai Medical Center·JournalJournal of Clinical Investigation·DateJun 8, 2022
Researchers developed a biopolymer film that combines anti-bacterial properties, inflammation dampening, and release of active pharmaceutical ingredients in a targeted manner. The film adheres to sensitive surfaces without damaging tissue, speeding up healing process and completely dissolving by itself.
SourceTechnical University of Munich (TUM)·JournalAdvanced Functional Materials·TypeExperimental study·DateMay 30, 2022
A team of engineers is working on a novel treatment using nanoparticles carrying therapeutic proteins to promote regeneration of blood vessels and muscle in injured limbs. The approach, which has shown promising results in animal models, aims to treat critical limb ischemia, a condition that can lead to amputation or death.
Researchers have found that light-based therapies such as photobiomodulation and photodynamics can effectively treat a range of post-COVID complications, including muscle and joint damage. The studies, conducted in Brazil, utilized laser irradiation, negative pressure, and other technologies to improve symptoms and promote healing.
SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalLaser Physics Letters·DateMay 24, 2022
Scientists from the University of Maryland developed CRISPR-Combo, a method to edit multiple genes in plants while simultaneously changing gene expression. This new tool enables genetic engineering combinations that work together to boost functionality and improve breeding of new crops.
SourceUniversity of Maryland·JournalNature Plants·TypeExperimental study·DateMay 23, 2022
Apple iPad Pro 11-inch (M4)
Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.
A CNIC team has created a dynamic 3D atlas of the formation of the heart during embryonic and fetal development, allowing for the identification of the first appearance of left–right asymmetry in the heart. This study provides important information on the development of congenital heart malformations.
SourceCentro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)·JournalNature Cardiovascular Research·TypeExperimental study·DateMay 17, 2022
A collaboration between researchers identified crucial minerals regulating gene expression to control tissue renewal and growth. Minerals such as silicon, magnesium, and lithium induce endochondral ossification by turning on key genes, leading to the transformation of stem cells into bone cells.
SourceTexas A&M University·JournalScience Advances·DateMay 6, 2022
A molecular switch, p57, enables stomach stem cells to change allegiance from normal digestion to injury response, potentially leading to new treatments for gastric pathologies. The study's findings suggest that p57 is a key regulator of reserve stem cell state in gastric chief cells.
SourceIMBA- Institute of Molecular Biotechnology of the Austrian Academy of Sciences·JournalCell Stem Cell·TypeExperimental study·DateMay 5, 2022
A team from the Terasaki Institute for Biomedical Innovation has created a method to repair tendons using silk fibroin scaffolds, which showed improved healing and regeneration of injured tendons. The scaffold combines silk fibroin with GelMA to promote cell attachment, growth, and differentiation.
SourceTerasaki Institute for Biomedical Innovation·JournalSmall·TypeExperimental study·DateMay 3, 2022
Celestron NexStar 8SE Computerized Telescope
Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.
Researchers have found a way to partially reset liver cells to more youthful states, allowing them to heal damaged tissue at a faster rate than previously observed. The use of reprogramming molecules improves cell growth and leads to better liver tissue regeneration in mice.
University of Virginia professor Rachel Letteri's lab designs polymers for healthcare applications, using peptide fragments to create hydrogels with tunable stiffness and lifespan. The team aims to develop materials that can support cell growth and guide tissue regeneration, with potential applications in regenerative medicine.
SourceUniversity of Virginia School of Engineering and Applied Science·DateApr 23, 2022
Researchers developed new method to visualize CNS fibroblasts and their intercellular interactions in the CNS. The technique provides a detailed picture of CNS fibroblasts, including their location, size, morphology, and gene/protein expression patterns.
SourceSPIE--International Society for Optics and Photonics·JournalNeurophotonics·DateApr 6, 2022
CalDigit TS4 Thunderbolt 4 Dock
CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.
Researchers at UC Riverside have discovered that curcumin promotes vascular endothelial growth factor (VEGF) secretion, helping to grow engineered blood vessels and tissues. The study uses magnetic hydrogels coated with curcumin-coated nanoparticles, which gradually release the compound without injuring cells.
SourceUniversity of California - Riverside·JournalACS Applied Materials & Interfaces·TypeExperimental study·DateApr 6, 2022
Researchers at the University of Illinois Chicago have identified two distinct subtypes of neutrophils, with one subtype being a drug target for treating inflammatory diseases. The discovery paves the way for more targeted therapies that address chronic inflammation without suppressing anti-infection functions.
SourceUniversity of Illinois Chicago·JournalACS Nano·TypeExperimental study·DateApr 5, 2022
Scientists at Texas A¼M University have created water-stable, 2D covalent organic framework nanoparticles that can guide human mesenchymal stem cells to form bone tissue. The new technology has the potential to impact the treatment of bone regeneration and improve drug delivery.
SourceTexas A&M University·JournalAdvanced Healthcare Materials·TypeNews article·DateMar 30, 2022