Articles tagged with Vision Disorders
A three-year study found that posterior scleral reinforcement slowed macular fundus tessellation and preserved subfoveal choroidal thickness in children with progressive high myopia. The researchers suggest that PSR may help delay early myopic maculopathy-related changes, possibly through mechanisms beyond axial elongation.
A study found a significant decrease in postoperative endophthalmitis rates after implementing a multifaceted surgical safety culture intervention, from 0.038% to 0.013%. The rate dropped by 64.4% among patients undergoing inpatient ophthalmic surgery.
Researchers tested cortisone eye drops to slow ROP progression in 100 premature babies. The intervention reduced treatment-requiring ROP by 47% compared to placebo.
Researchers developed a prototype imaging system that can simultaneously track the cornea's mechanical response at nine locations, allowing for more accurate assessment of corneal biomechanics. This technology has the potential to improve early detection and monitoring of disorders like keratoconus.
A nationwide analysis of over 18 million patients found a 30% higher risk of developing retinal vascular disease in the month following the spring clock change, while a 20% lower risk was observed in the fall. The study suggests that gaining an hour of sleep may be protective against disease risk.
A researcher at the University of Minnesota Medical School has been awarded a $3.7 million NIH grant to develop robust AI models for primary open-angle glaucoma prognosis. The project aims to improve patient outcomes by identifying patients at high risk of vision loss earlier and more accurately.
Scientists have identified a previously unknown waste drainage system at the back of the eye, called the posterior ocular lymphatic outflow, or POLO pathway. This discovery provides a new framework for understanding leading causes of blindness and opens opportunities for harnessing this system to treat disease.
A new class of photoswitchable small molecule drugs has been developed to restore key visual functions in animal models of blindness. These compounds mimic the function of photoreceptor cells and show remarkable effectiveness at restoring sight using a simple and potentially patient-friendly approach.
Researchers found a slight association between GLP-1 medications and ischemic optic neuropathy, a condition causing reduced blood flow to the optic nerve. The risk remains low, but clinicians should be aware of this potential association, particularly in patients with Type 2 diabetes.
A multicenter study found that patients with irregular corneas achieved significant visual acuity improvements after wearing a four-zone scleral lens for three months. The lenses showed encouraging fitting efficiency and patient comfort, with minimal adverse events reported.
A new study published in Ophthalmology Science has confirmed that The CVI Range Assessment is a valid and reliable instrument for evaluating functional vision in children with Cortical Visual Impairment (CVI). This finding provides evidence that the widely used assessment meets rigorous clinical and psychometric standards, offering a s...
Dr. Lisa Ostrin and Dr. Sayan Ghosh join SUNY Optometry to expand expertise in myopia, ocular development, and age-related macular degeneration. Their research aims to improve patient care, public health, and vision science.
A study from Linköping University finds that mild COVID-19 can lead to long-term eye problems, including abnormal pupil function and strabismus, affecting daily life. Researchers developed a diagnostic model to detect these issues, which may lead to effective treatment.
SUNY Optometry is expanding its research in oculomics with a $434,522 grant from the SUNY Empire Innovation Program. The funding will support the recruitment of a new faculty researcher, advancing the field's connection between vision science and systemic health.
The STOC-T technology resolves optical noise in eye imaging by fundamentally changing the way imaging data is collected, resulting in sharper images and improved diagnostic accuracy. This new approach addresses the problem earlier, before image construction, rather than relying on post-processing algorithms.
A recent study published in Eye Discovery evaluated the early visual quality after KLEx surgery using the VISUMAX 800 platform. The study found excellent safety and efficacy outcomes, with most subjective visual symptoms improving over time. However, glare symptoms persisted longer than expected, highlighting the need for preoperative ...
Using a massage gun on or around the eyes can cause major tearing and bruising to the retina, warns a recent case report. The device's rising popularity highlights the need for clearer manufacturer guidelines and standardised use instructions to prevent such injuries.
A nationwide population-based study found that individuals with neovascular age-related macular degeneration had a modest but statistically significant increase in overall cancer risk. However, the increased risk was only observed for specific malignancies, including thyroid, kidney, and prostate cancers.
A University of Minnesota Medical School research team has been awarded a 4-year, $2.2 million grant to better understand the underlying causes of retinal diseases like age-related macular degeneration (AMD) and develop new treatments. The focus is on fibulin-3, an extracellular matrix protein that causes blinding eye diseases.
A pediatric ophthalmologist is leading a $1 million NIH grant to study the genetics of cataracts in children. The goal is to develop a comprehensive AI-assisted database of genes associated with potential diseases.
A new study from Johns Hopkins Medicine found that an AI-assisted diagnostic tool increased referrals for African American patients with diabetes, resulting in more people receiving necessary eye exams. The study suggests that integrating such tools could help address healthcare disparities in underserved populations.
A new set of consensus standards for classification, annotation, and quality control is being implemented for artificial intelligence applications in dry eye imaging. These standards aim to enhance consistency and multicenter collaboration in AI-assisted diagnosis.
Odylia Therapeutics is advancing a gene therapy treatment for Usher Syndrome Type 1C (USH1C)-associated vision loss, a rare autosomal recessive disorder. The grant will support the development of an investigational USH1C gene therapy designed to restore or preserve vision.
A major new study has found that severe asthma patients are often battling other health conditions, with nearly all suffering from at least one major issue. The study identified three distinct profiles linked to how well asthma is controlled and the treatments needed, offering potential breakthroughs for improving care.
The article discusses how AI is unlocking hidden potential in multimodal ophthalmic datasets, enabling high-precision screening and early detection of eye diseases. It highlights the integration of various imaging modalities and non-imaging data types to provide a comprehensive diagnostic framework.
The study utilizes high-sensitivity LC-MS to quantify TCA cycle intermediates in mouse ocular tissues, revealing dual differences in metabolic characteristics based on spatial distribution and biological sex. Key findings include tissue-specific metabolic phenotypes and sexual dimorphism of metabolic profiles.
A major international study has identified a genetic contributor to juvenile glaucoma, which can affect people before the age of 40. The study found that individuals with a specific genetic duplication have an increased risk of developing the condition, and may benefit from routine testing.
A new study published in Eye and Vision finds that one drop of low-dose atropine can produce daylong effects in managing myopia. The researchers found that the drop showed clear changes in pupil size and focusing ability, but no short-term structural effects on the eye.
A Tohoku University research group developed an AI model that estimates retinal age from a fundus photograph, reflecting biological aging and potential disease risk. The model is non-invasive and can be used as a screening aid, identifying patients who may need further health assessments.
Researchers developed MitoCatch, a system that targets disease-affected cells with healthy mitochondria. The innovation enables efficient cell type-specific mitochondrial delivery, improving survival of damaged neurons in vitro and retinal ganglion cells in vivo.
A study by the University of Turku reveals that assistance dogs actively contribute to their human's care through continuous interpretation and trust. They anticipate health status, provide mobility assistance, and offer emotional support in ways that humans cannot.
Researchers at Binghamton University have created a talking robot guide dog system that determines ideal routes and guides visually impaired users safely to their destinations. The system offers real-time verbal feedback and provides situational awareness, significantly enhancing the user experience.
Researchers linked neural activity to blind individuals' ability to determine object location using echolocation. Accuracy improved with repeated mouth clicks, suggesting a summation of information in the brain.
A new portable AI-powered scanning slit-light device makes low-cost eye disease screening more accessible, providing quantitative measurements and qualitative assessments of anterior-segment abnormalities. The lightweight AI model allows for on-device analysis, reducing operator dependence and improving portability.
A retrospective cohort study in primary care found that patients with floaters or flashes have a higher risk of retinal detachment. The study, published in the Annals of Family Medicine, analyzed data from 1,181 episodes and found that new or recently changed acute floaters were associated with a higher relative risk.
Researchers at the University of Pittsburgh School of Medicine develop an experimental 'living eye drop' using naturally occurring eye bacteria to accelerate corneal wound healing. The engineered bacteria, Corynebacterium mastitidis, continuously secrete interleukin-10, a protein that regulates inflammation.
A University of Houston optometry researcher warns of the dangers of red-light laser myopia therapy for children, citing vision damage reports and the need for rigorous safety validation. The professor's quality improvement study found that two popular devices exceeded national standards for safety classifications.
A study published in Cornea reveals that aniridia not only alters corneal structure but also affects sensory nerve function, leading to a progressive decline in corneal sensitivity. In adulthood, patients experience difficulty distinguishing stimulus intensity and reduced tear production, compromising eye defense mechanisms.
A new study proposes that myopia is driven by how we use our eyes indoors, with prolonged close-up focus in low-light environments limiting retinal illumination. This mechanism could lead to a paradigm shift in understanding and controlling myopia progression and control.
Research reveals a strong association between telomere length and age-related cataract risk, with longer telomeres linked to lower cataract incidence and milder lens opacity. The study's findings position telomere length as a biological indicator of systemic aging processes and visual health.
Researchers found that patients with substance use disorder received life-saving treatments only when addiction consult services were involved. Fentanyl use was associated with dramatically worse visual outcomes, highlighting the importance of addressing underlying conditions alongside acute medical problems.
A blind patient partially recovered natural vision through electrical stimulation of the visual cortex, independent of the implant. The recovery was sustained over time and remained even after the device was removed, suggesting individual factors may have contributed to this outcome.
Researchers found metformin reduces progression of AMD by 37% in people over 55 years, a breakthrough in search for new treatments. The study used pictures from 2,000 eye screenings and adjusted for factors like age, sex, and duration of diabetes.
Researchers used MRI analysis to measure glymphatic system activity, finding changes related to IIH stage and pressure levels. The findings suggest a noninvasive test could diagnose IIH more reliably, improving treatment options for patients with symptoms including headaches and vision loss.
A WVU research team is working to restore vision in people with inherited blindness due to genetic mutations in the Prominin1 gene. The team has observed encouraging early results using a mouse model and plans to investigate the therapy's effectiveness beyond initial restoration.
A new study estimates that over 1.6 million people in the UK will be living with glaucoma by 2060, with nearly 50% higher prevalence than previous estimates. The researchers call for expanded eye health services and increased awareness campaigns to detect early cases and prevent vision loss.
A new study from Nagoya University in Japan has found that petrolatum-based eye ointments can cause MicroShunt glaucoma implants to swell and potentially rupture. The study suggests that clinicians should avoid using these ointments on patients with the implant, particularly when it is exposed outside the conjunctiva.
A new study demonstrates the effectiveness of a widely-used eye injection in managing hypotony, a rare condition characterized by abnormally low eye pressure. The treatment, which involves injecting HPMC gel, has shown promising results in restoring vision and increasing eye pressure.
A new study by Mass General Brigham researchers found that genetic variants thought to always cause inherited blindness occur in only 28% of people who carry them. The findings challenge traditional models of rare disease genetics, suggesting a need for updated understanding and potentially impacting the development of new treatments.
Philip R. Troyk, director of the Pritzker Institute of Biomedical Science and Engineering at Illinois Tech, has been elected as a Fellow of the National Academy of Inventors for his groundbreaking work on neuroprosthetic devices, including an implanted cortical visual prosthesis that provides artificial vision to individuals with profo...
A study has revealed that reticular pseudodrusen, associated with increased risk of vision loss in AMD, are driven by pathways on chromosome 10 and not by genetic risks on chromosome 1. The discovery highlights the need for novel treatment approaches for different AMD subtypes.
A new study at Rice University found that individuals with age-related macular degeneration (AMD) can accurately estimate the arrival time of an approaching vehicle using a combination of visual and auditory cues. Despite impaired central vision, participants relied on both modalities to make collision judgments.
Researchers tracked 120 older veterans taking gabapentinoids and loop diuretics, finding that only 4 doctors correctly identified the gabapentinoids as the cause of leg swelling. The study highlights the dangers of 'prescribing cascades' and emphasizes the need for regular monitoring and alternative treatment options.
A new computer modeling approach has simulated retinal development and identified key stages of cell diversification. The research paves the way for understanding retinal diseases and regenerative research using stem cells.
A new poll suggests that more than 80% of people over 65 drive at least weekly, but less than half have made a plan for when they can no longer drive safely due to health changes. Only 6% of older drivers have discussed their driving with a healthcare provider.
University of Minnesota researchers found that reducing chronic inflammation can significantly protect against age-related macular degeneration (AMD)-like pathology in preclinical models. The strategy aims to intervene before severe damage occurs, potentially delaying or preventing vision loss for those with early signs of AMD.
A new MIT study reveals that temporarily anesthetizing the retina of the amblyopic eye can restore its neural connections and improve vision in adulthood. The treatment, which has been shown to be effective in infancy and early childhood, may have promising clinical potential for adults with amblyopia.
Researchers at Ritsumeikan University have discovered that the loss of TRPM1 ion channels sets off a cascade of changes leading to persistent oscillations in the retina. This finding illuminates the cellular basis of congenital stationary night blindness and identifies a common mechanism underlying retinal degenerative conditions.
Researchers will study neural mechanisms of visual perceptual learning (VPL) to generalize across the visual field, improving vision rehabilitation and AI systems. The project aims to develop a unified model of visual processing, VPL, and attention.
A study by neuroscientists found that babies born blind retain the ability to recognize faces and objects, but not small details like contours, in their brains. The research suggests that early vision loss may not hinder brain development as much as previously thought, paving the way for new visual therapies.