Researchers have identified a previously unknown mechanism that can reduce the risk of allergies and asthma in children. Certain bifidobacteria produce a substance called 4-hydroxyphenyl lactate (4-OH-PLA), which dampens immune responses to allergens, reducing the production of IgE antibodies.
The study will select the exact phage that is appropriate for each patient's bacteria, and aims to reduce antibiotic use and healthcare costs. Bacteriophages have been shown to be effective against resistant bacteria causing urinary tract infections.
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A Northwestern University study found that airplane and hospital air mostly contain harmless microbes from human skin, with some potentially pathogenic species in extremely low abundance. The study used worn face masks as a passive tool to monitor indoor air, revealing the invisible world of microbes floating in our shared air.
The discovery of five new bacteriophages in Lund University's Botanical Gardens' ponds has significant implications for phage research and treatment of bacterial infections. The newly-discovered phages were isolated using a motile E. coli strain, which was specifically designed to attract the viruses.
Researchers at the University of Houston discovered that T. phoenicis can enter dormancy to evade detection, highlighting the resilience of spacecraft-associated microbes and raising concerns about planetary protection. The findings may lead to better detection methods and more effective sterilization strategies in various industries.
Researchers at DTU have discovered a way to combat antibiotic-resistant bacteria by nourishing special bifidobacteria that is naturally occurring in the gut. Special lactic acids produced by bifidobacteria play a key role in keeping antibiotic-resistant bacteria at bay.
A new study found that probiotics significantly reduced the presence of antibiotic-resistant bacteria and multidrug-resistant bacteria in the infant gut, while also promoting a more typical gut microbiome. This breakthrough has major implications for the global AMR crisis, particularly for preterm infants.
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Researchers use surface-enhanced Raman spectroscopy to analyze vaginal fluid biochemical fingerprints, detecting specific bacterial species like Lactobacillus iners. The portable device produces comparable results to high-end lab equipment, suggesting its potential for point-of-care monitoring.
Researchers discovered a compound, EPS3.9, produced by deep-sea bacteria that triggers pyroptosis to inhibit tumor growth and exhibit potent anti-cancer effects. The study highlights the importance of exploring marine microbial resources for developing new drugs.
Scientists identified a unique protein in bacteria that can trap parts of the membrane, causing damage to other bacteria. This discovery reveals a new 'superfamily' of lipid-trapping proteins, which could have implications for antibacterial development and synthetic biology.
Researchers found that immunocompromised animals respond better to phage therapy due to depleted alveolar macrophages, which initially seemed to hinder its efficacy. The study highlights the importance of the immune system in phage therapy and may inform personalized treatment strategies.
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Researchers have identified genetic bottlenecks that explain the emergence of pandemic cholera strains. These specific combinations of genes and allelic variants grant an advantage in human intestinal colonization, allowing a small subset of Vibrio cholerae to become deadly pathogens.
Researchers have found new organisms that can capture carbon dioxide and clean pollutants from the environment. By exploring extremophiles in homes, scientists can gain insights into their unique characteristics and develop sustainable solutions.
A recent study suggests that highly diverse microbial ecosystems may actually decrease stability under stress conditions. In contrast, low-diversity ecosystems often exhibit increased growth rates and community stability when faced with starvation or high salinity.
A new study by Virginia Tech researchers suggests that bacteriophages, or virus-like particles, may increase the sensitivity of gut bacteria to antibiotics. The team created a mouse model that allows them to control phage populations and found evidence that phages can exacerbate antibiotic damage.
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A new paint with a built-in bacteria-killing agent has been found to effectively kill MRSA, flu and COVID-19 on various surfaces. The paint, developed by scientists at the University of Nottingham, uses chlorhexidine to create an antimicrobial coating that can be applied to plastic and hard non-porous surfaces.
Scientists have identified a novel species of bacteria that acts as electrical wiring, enabling long-distance electron transport and potential applications in medicine, industry, and environmental monitoring. The new species, Ca. Electrothrix yaqonensis, is named after the Native American Tribe of the region where it was found.
Researchers found that pheasants released in the UK can carry Lyme disease bacteria in ticks, increasing the risk of human exposure. The study suggests 'spillback' from non-native species can lead to the emergence of zoonoses.
Researchers at MD Anderson Cancer Center have discovered that adding copper-loaded agents to radiotherapy can overcome radioresistance in preclinical models of thoracic cancer. A novel blood-based biomarker, OSMR, has also been identified in patients with acute myeloid leukemia (AML), which shows prognostic potential and can help ident...
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Researchers found that nutrient hoarding by selfish bacteria influences carbon and nutrient availability in freshwater ecosystems. In two Croatian lakes, mesotrophic Crniševo Lake showed higher rates of selfish activity than oligotrophic Kozjak Lake.
A cross-disciplinary research team from HKU has found a connection between oral microbiota and ASD, identifying 11 bacterial species as potential biomarkers. The study developed a prediction model with an 81% accuracy rate for early detection, paving the way for non-invasive screening tools during dental check-ups.
Researchers found that bacterial movement and flagellar rotation activate conjugation genes, enabling DNA transfer in liquid environments. This discovery provides insight into the spread of antibiotic resistance across species.
A study analyzing over 3 million bacterial samples found that antibiotic resistance initially rises but stabilizes over time, reaching an equilibrium in most species. The study suggests that continued increase in antibiotic resistance is not inevitable and provides new insights to monitor drug resistance.
Researchers found two new types of gene clusters capable of producing large volumes of hydrogen in marine bacteria. The study suggests that the diversity in these clusters is related to speciation and ecological niches, with some species producing higher levels of hydrogen than others.
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A research team has identified a previously unknown defense mechanism in Pseudomonas syringae, enabling the bacterium to produce chemical compounds that attract amoebae, which are then killed by toxic substances produced by the bacteria. This 'chemical radar' system also helps the bacteria infect plants in the presence of predators.
Researchers discovered that certain marine diatom species can thrive on a diet of seaweed and decaying plant matter due to the acquisition of a bacterial gene. This adaptation allowed them to break down alginate, a carbon polymer in seaweed cell walls, enabling the diatoms to survive without photosynthesis.
Researchers demonstrate a new technique for encapsulating beneficial bacteria that can be stored and applied to plants to improve growth and protect against pests. The technique enables customized probiotics for plants, allowing farmers to use these bacteria in conjunction with agrochemicals.
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A UMass Amherst Ph.D. student has been awarded a €20,000 grant to investigate a new therapeutic target for Lyme disease by targeting the GuaB enzyme necessary for Borrelia burgdorferi replication in mammals.
Researchers discovered that sulfur bacteria from the Desulfobacteraceae family work together like a team to break down diverse organic compounds. By analyzing six strains, they found similar molecular strategies and a highly energy-efficient central metabolism pathway, enabling them to thrive in oxygen-free environments.
Scientists have uncovered the molecular structure of Mycoplasma mobile's twin motors that power its gliding ability, using cryo-electron microscopy. The complex structure reveals a new mechanism by which energy from ATP hydrolysis is converted into motility.
Researchers from the University of Surrey found that a balance between reactive nitrogen species and reactive oxygen species affects drug-resistant bacteria. The study suggests treatments boosting reactive nitrogen species may be effective against antibiotic-resistant bacteria.
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Researchers have discovered that giraffes maintain species-specific gut flora, even when eating different sets of plants. This finding has significant implications for the conservation of endangered giraffe species, highlighting the importance of understanding their diets and habitats to ensure their survival.
Researchers from Nagoya Institute of Technology have shed light on the mechanisms of bacterial flagellar motors, which propel bacteria through fluids. The study used CryoEM to capture high-resolution images of stator complexes and identified key molecular cavities for sodium ions.
A global 'sisterhood' of citizen scientists sheds light on the complex vaginal microbiome, highlighting associations between microbial composition and clinical conditions like preterm birth and urinary tract infections. The study emphasizes the importance of considering whole complexity and continuity in vaginal microbiota composition ...
Researchers identified a potential mechanism linking sugary beverage consumption to diabetes risk through alterations in the gut microbiome and blood metabolites. High sugar-sweetened beverage intake was associated with changes in bacterial species that produce short-chain fatty acids, negatively impacting glucose metabolism.
A recent study found that Streptococcus anginosis, a common mouth bacteria, is abundant in the guts of people with acute stroke and linked to a worse prognosis. The researchers also discovered that levels of this bacteria were associated with increased mortality rates two years after stroke.
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A study identified unique microbiome signatures associated with Nonalcoholic Fatty Liver Disease (NAFLD), allowing for precise diagnoses and new therapeutic approaches. These signatures predict bacterial metabolites and are linked to the development of NAFLD, providing insights into disease mechanisms.
Researchers found that a person's microbiome signature can predict the likelihood of Enterobacteriaceae colonization. Fiber-rich foods support the growth of beneficial Faecalibacterium, which produce short-chain fatty acids protecting against infection.
Physicists at MIT have devised a formula predicting which invasive species will succeed in an ecosystem, based on analysis of soil bacteria. The researchers found that population fluctuations are key to invasion success, and that diversity can either help or hinder the invader.
Researchers found that soil contains antibiotic resistance genes that can be transmitted to humans, making it a pressing public health threat. The study reveals how these genes spread through the environment and highlights the importance of understanding soil ecosystems to control antibiotic resistance.
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Researchers found unique signatures in household plumbing microbiomes, with wide variation from house to house. They also detected antibiotic resistance genes, highlighting the need for better monitoring and prevention strategies.
Researchers have identified a link between bacteria and kidney stone formation, finding that low levels of E. coli and Lactobacillus promote or prevent kidney stone development. The study suggests that the urinary tract is not sterile and that antibiotic misuse can skew the microbiome towards stone-promoting bacteria.
Researchers identified five fungi species with toxic effects against the bacterium, which disrupts cellular levels of thiols essential for bacterial survival. The findings support a strategy for developing treatment-shortening drugs by targeting biological processes maintaining thiol levels.
Researchers at Tokyo University of Science have developed a novel co-culture system that facilitates cultivating multiple indigenous skin bacteria in a balanced state. This breakthrough allows for detailed analysis of the biology of indigenous skin bacteria, which can lead to new treatments for skin diseases and improved quality of life.
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Antibiotic consumption in the EU increased by 1% between 2019 and 2023, moving further away from the 2030 target of a 20% reduction. Despite significant reductions in methicillin-resistant Staphylococcus aureus bloodstream infections, carbapenem-resistant Klebsiella pneumoniae bloodstream infections worsened, with an increase in incide...
Researchers at Tufts University discovered that TB bacteria maintain a consistent growth rate throughout their life cycle, defying expectations. The study also reveals new growth behaviors of TB bacteria, including the ability to grow from either end after division.
A new study developed a machine-learning model to predict microbial load, the density of microbes in our guts. The model revealed that many factors can influence microbial load, including lifestyle, diseases, and medications.
A recent machine learning study suggests that the association between gut bacteria and disease may be overstated. Instead, changes in microbial load were found to be a key factor in the presence of disease-associated microbial species. This discovery challenges current understanding of the gut microbiome's role in disease etiology.
A new study by the University of Exeter and Wageningen found that Asaia bacteria accelerate the development of mosquito larvae, potentially boosting mass-rearing schemes. This could lead to more effective global health programmes against diseases like dengue, yellow fever, and Zika.
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Researchers have discovered two previously unknown bacterial species in deep-sea corals from the Gulf of Mexico. These bacteria have extremely reduced genomes and lack the ability to break down carbohydrates, surviving on amino acids instead. The discovery provides insights into the unique adaptations of deep-sea organisms.
A new study reveals how three species of bacteria coexist in biofilms by playing a game of 'nice' and then moving out when the surface becomes too crowded. The dominant species, Pseudomonas aeruginosa, disperses to allow other species to thrive.
A team of researchers has identified mangrove bacteria that can transform polyethylene terephthalate (PET) particles, which are a major contributor to ocean pollution. The discovery of novel enzymes and bacterial species with the ability to break down PET could potentially be used to develop new strategies for plastic waste cleanup.
Providencia rustigianii carries a type III secretion system and cytolethal distending toxin virulence gene, increasing its pathogenicity, similar to Salmonella.
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A new study has identified novel strains of microbes that have adapted to use limited resources in cities, including those found in Hong Kong's subways and skin. These microbes can metabolize manufactured products, posing health risks if they are pathogenic.
A team of researchers discovered a mechanism that determines the spiral shape of Rhodospirillum bacteria, revealing a novel link between cell shape and fitness. The study found that an outer membrane porin-lipoprotein complex modulates elongasome movement to establish cell curvature in R. rubrum.
A new study found that over a dozen bacterial species in the oral microbiome are linked to a 30-50% increased chance of developing head and neck squamous cell carcinoma. The research analyzed data from 159,840 Americans and identified key bacteria that may contribute to the disease.
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Researchers discovered that certain bacteria display communal behaviors protecting sensitive species from drugs, allowing them to grow normally in a community. The study found that high drug concentrations cause microbiome communities to collapse and cross-protection strategies are replaced by cross-sensitisation.
A new study shows that breastfeeding beyond three months supports the gradual maturation of a baby's microbiome, which lowers their risk of developing asthma. The study found that breast milk regulates the mix of microbes in infants, setting the pace and sequence for microbial colonization.
Blanca Barquera's research aims to improve understanding of the energy metabolism of Bacteroides, a crucial step towards designing effective probiotic formulations. The study will investigate how Bacteroides utilize carbohydrates and Vitamin K from host diets.
A new study from European universities has developed a method to analyze wastewater data from seven major cities, identifying thousands of disease-causing bacteria, viruses, and antimicrobial resistance. This approach can detect potential health threats simultaneously, potentially preventing epidemics from escalating into outbreaks.
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