Articles tagged with Blood
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers developed an AI tool called ONCO-ACS to predict the risk of secondary heart attacks in cancer patients after a heart attack. The tool combines cancer-related factors with standard clinical data to provide reliable information for doctors to balance treatment benefits and harms.
Researchers have developed a fast and easy test that can track the aging process of red blood cells after storage, potentially improving the quality of blood transfusions. The device uses surface acoustic waves to detect changes in metabolites associated with aging cells.
A new blood test has identified a protein signature linked to cancer in patients with non-specific symptoms. The test distinguishes cancer from other conditions with high precision and can help prioritize patients for further diagnostics.
A large study found that home fingertip oxygen monitors give higher readings for patients with darker skin tones, which can lead to missed diagnoses and delayed medical attention. The researchers suggest interpreting SpO2 readings in context and developing guidance to address these limitations.
A new study from Karolinska Institutet identified seven blood biomarkers that predict the risk and progression of multimorbidity in older adults. These biomarkers reflect biological processes such as metabolism, inflammation, and neurodegeneration.
Researchers develop ex vivo treatment of blood stem cells with Rhosin, a RhoA inhibitor, to rejuvenate them and improve the production of healthy blood cells. This strategy targets the core of the ageing process, making blood stem cells more capable of regenerating and producing new healthy blood cells.
A new study by UC San Francisco combines genetic risk with cardiovascular disease risk factors to predict who is more likely to develop dementia. The expanded view may help those worried about dementia, as lifestyle changes and improved control of illnesses can reduce brain damage and potentially delay or prevent symptoms.
A team of scientists at the University of Tokyo has developed an automated, high-throughput system that uses machine learning to analyze droplets of biofluids for disease diagnosis. The technology relies on imaging drying processes to distinguish between normal and abnormal samples.
Researchers at Tokyo University of Science identified genes that predict CD8+ T cell expansion in cancer immunotherapy. A 'signature gene set' or 'expansion signature' was found to identify primed T cells for growth, predicting treatment response and offering a potential guide for new therapies.
Scientists analyzed thousands of proteins in blood samples to understand when multiple sclerosis attacks the myelin sheath and nerve fibers. Researchers identified a protein called IL-3, which plays a key role in this early phase of damage.
Researchers discover that genetic glitches in the blood system, caused by aging, can spark obesity, diabetes, and fatty liver disease. Simple blood tests may help identify at-risk individuals to prevent chronic illnesses.
Researchers at the University of Cambridge have developed a new lab-grown human embryo model that replicates early human development, including the production of blood stem cells. The 'hematoids' model mimics the natural developmental process, offering potential medical advances in screening drugs and studying blood disorders.
Researchers at UBC have successfully transplanted an enzyme-converted kidney into a brain-dead recipient, showing promise for universal donor organs in transplantation. The breakthrough uses special enzymes to remove blood-type antigens, making it possible to use mismatched organs from deceased donors.
Heiko Yang, MD, PhD, has received a grant from the National Institutes of Health (NIH) to further research on his discovery of an earthworm-derived hemoglobin-like oxygen carrier. This substance has the potential to revolutionize organ perfusion by providing a shelf-stable alternative to donor blood.
Researchers found that higher SDMA levels, but not ADMA, correlated with weaker blood vessel function in patients with moderate chronic kidney disease. This suggests that measuring SDMA levels may provide a better approach to monitoring vascular function in these patients.
Researchers found tiny air pollution particles sticking to red blood cells after exposure to roadside pollution, which can travel to organs like brain and heart. Wearing an FFP2 face mask reduces the amount of particles stuck to red blood cells.
Scientists develop a revolutionary 'blood on demand' technology that can preserve red blood cells for extended periods, reducing thawing and washing times. This innovation has the potential to transform emergency medicine and provide a reliable blood supply in crisis situations.
A new blood-based biomarker study identifies a link between self-reported cognitive decline and blood-based biomarkers, paving the way for a simple blood test to diagnose Alzheimer’s disease and related dementias. The approach could be faster, less-invasive, and more affordable than existing screening tools.
Researchers at UCSF screened hundreds of industrial dyes to identify those that stick to protein clumps in the brain, a hallmark of dementia. They found 10 sure hits that illuminated tau clumps in animal models and human samples, offering new hope for diagnosis and treatment.
Researchers discovered that inflammatory bowel disease (IBD) leads to blood clotting due to a lack of layilin protein, which prevents platelets from forming unwanted clots. A drug targeting Rac1 activity could reduce excessive clotting and alleviate day-to-day IBD symptoms.
Researchers at University of Pennsylvania discover red blood cells contribute to clot contraction, shrinking and stabilizing blood clots. The finding opens door to new strategies for studying and treating clotting disorders, such as excessive bleeding or dangerous clots like those seen in strokes.
Researchers investigated the impact of skin pigmentation on pulse oximeter accuracy, finding that darker skin reduces red light absorption and affects oxygen level detection. This study provides experimental evidence for improving pulse oximeter accuracy across all skin tones.
A new study has provided insights into how blood stains cotton fabrics, allowing investigators to gather additional information from forensic evidence. The researchers found that the number and spread of 'fingers' in the bloodstain correlate to the velocity of the blood spatter, with faster-moving blood leaving more prominent tendrils.
A new study shows that a simple blood test taken in the first trimester of pregnancy can accurately identify women at risk of developing preeclampsia five months before clinical diagnosis. The test uses cell-free RNA, or cfRNA, to capture subtle molecular signals from multiple maternal tissues.
A circulating tumor DNA-based blood test demonstrated acceptable accuracy for colorectal cancer detection in an average-risk population. However, it struggled to detect advanced precancerous lesions, highlighting the need for further improvements.
A cohort study found that lower-than-recommended lead levels were associated with worse academic grades, suggesting the need to reconsider current blood lead reference values for further interventions. The findings support lowering these values to improve outcomes for children and adolescents.
Researchers developed a technique to analyze DNA methylation marks, identifying changes in blood production that occur with age. By age 50, many blood stem cells begin to drop out and larger clones take over, leading to a decline in diversity and resilience.
Researchers from USC Keck School of Medicine have developed a low-cost blood test that detects five biomarkers of Alzheimer's disease, including amyloid and tau proteins. The test uses xMAP technology and has the potential to catch the disease in its earliest stages, when treatment might be able to prevent or delay cognitive decline.
Researchers developed a new imaging technique that uses artificial intelligence and high-speed microscopy to track platelet behavior in real-time. The study shows promise for personalizing heart disease treatment by monitoring clotting risk in patients with coronary artery disease.
A systematic review and meta-analysis found that individuals with blood type A have a significantly higher risk of developing breast cancer compared to those with blood type O. The research, which pooled data from over 13,000 breast cancer patients and 717,000 controls, suggests an 18% increased risk associated with blood type A.
Research from the University of Oklahoma suggests that women with adequate iron levels in their blood perform better on cognitive tasks during menopause. Having enough iron does not necessarily mean accumulating more iron in the brain, which is a risk factor for neurodegenerative diseases like Alzheimer's.
Researchers found that measuring lipoprotein markers in a simple blood test can identify individuals at high risk of cardiovascular disease more effectively. The study analyzed data from over 200,000 people and showed that the total number of 'bad cholesterol' particles is the most important factor to consider when testing for future h...
Researchers used umbilical cord blood to analyze genetic changes linked to metabolic dysfunction in children. The study found multiple regions of altered DNA associated with metabolic issues later in childhood.
Researchers at UCL developed a new scoring system, CAR, to identify patients with narrowed carotid arteries who can be effectively treated with optimised medical therapy. The study found low rates of recurrent strokes and heart attacks among patients treated with medication alone.
A study has identified an early blood marker for hereditary Alzheimer's disease, beta-synuclein, which can detect neurodegeneration up to 11 years before dementia symptoms. This biomarker could help with early diagnosis and treatment, improving the potential of new medicines for Alzheimer's.
A new study suggests a changing climate threatens the continuous availability of safe blood across the world. Researchers warn that warmer temperatures, natural disasters, and infectious diseases will impact the ability of people to donate and trigger a rise in blood demand.
Researchers developed a simple, cost-effective blood test that detects Parkinson's disease long before symptoms emerge by analyzing transfer RNA fragments. The test has an accuracy surpassing existing clinical diagnostic tools and may alleviate uncertainty faced by patients and clinicians.
A new study published in Transfusion journal reveals sex-based disparities in the transfusion of whole blood to traumatically injured patients. Women, particularly younger females and those of childbearing potential, are less likely to receive whole blood transfusions compared to men. This disparity is despite whole blood being associa...
Researchers have identified a potential precision medicine approach to prevent chronic kidney disease progression by targeting type 5 collagen, a minor component of scar tissue. A repurposed anti-cancer drug, Cilengitide, has been shown to slow kidney scarring and disease progression in high-risk individuals.
Tulane University scientists developed a handheld device to deliver rapid and accurate tuberculosis diagnoses in under an hour. The device, called the lab-in-tube assay (LIT), can detect Mycobacterium tuberculosis DNA in saliva, blood, and sputum samples, offering a cost-effective tool for improving TB diagnoses in resource-limited areas.
A study found that pedometers capture a remarkable 88% of the health information provided by more advanced accelerometer measurements. Walking at a brisk pace is essential for cardiovascular health optimization, with a minimum cadence of 80 steps per minute strongly associated with good aerobic fitness.
Researchers created a thromboinflammation-on-a-chip model that can sustain blood clots for several months and track treatment options. This model reveals critical information on clot resolution and suggests new drug combinations to protect endothelial function in patients with sickle cell disease.
A new paper highlights emerging alternatives to traditional diabetes medicines, such as continuous glucose monitors and lifestyle interventions like GEM, which can improve patient adherence and long-term health outcomes.
The SUMMIT trial shows tirzepatide reduces the risk of cardiovascular death or worsening heart failure in patients with obesity, chronic kidney disease, and heart failure, while improving kidney function. Researchers found significant improvements in both patient groups with and without chronic kidney disease.
Researchers at Penn State are developing a next-generation synthetic blood substitute called Nano-RBC, which mimics the shape and movement of human red blood cells. The new blood substitute aims to address the shortage of safe blood sources quickly enough for trauma patients, with potential applications in rural or war-torn areas.
A new study found that three months of dual antiplatelet therapy (DAPT) was better than one month for reducing heart attacks, strokes, and other adverse events without increasing bleeding risk in high-risk patients. For low-risk patients, three months of DAPT was comparable to 12 months in reducing adverse events, while being better th...
A new study found that smartwatches paired with a health app can encourage people with newly diagnosed Type 2 Diabetes to maintain a home-delivered, personalised exercise programme. This programme showed improvements in blood sugar levels, systolic blood pressure, cholesterol, and quality of life.
A study found that consuming sucralose alters brain activity related to hunger and increases appetite, especially in people with obesity. The sugar substitute changes how the hypothalamus communicates with other brain regions, including those involved in motivation, potentially leading to cravings and eating behavior changes.
A new study found that smartwatches paired with a health app can encourage people with newly diagnosed Type 2 Diabetes to start and maintain purposeful exercise, leading to improvements in blood sugar levels and systolic blood pressure. The programme also helped participants lower cholesterol and improve their quality of life.
People with heart failure who can travel outside their home without assistance are less likely to be hospitalized or die within a year. Life-space mobility, a measure of how far patients move in their communities, is a reliable marker of risk for adverse outcomes in chronic diseases.
Researchers have developed a way to activate adult stem cells from human bone marrow, enabling their expansion outside the body for use in bone marrow regeneration. The new method significantly improves transplant success rates for patients with genetic disorders or those who require a bone marrow transplant.
The Dexcom G7 CGM device demonstrated an accuracy of 8.0% in a study involving 130 adults with type 1 or type 2 diabetes, setting a new standard for continuous glucose monitoring devices.
Researchers found that patients who received non-compliant care had more complex medical conditions and were more likely to present with unusual symptoms. The study's findings challenge the assumption that SEP-1 compliant care is associated with better survival, highlighting the need for risk-adjusted outcome measures.
A team of scientists has successfully developed a novel platform for diabetes treatment utilizing bioink derived from pancreatic tissue and 3D bioprinting technology. The HICA-V platform replicates the structure and function of the human endocrine pancreas, supporting islet maturation and functional enhancement.
Researchers at the University of Virginia Health System have developed a computational tool called LogiRx that can predict how drugs will affect biological processes in the body. The tool has demonstrated its potential by identifying a promising candidate to prevent heart failure, a leading cause of death worldwide.
A study from Aarhus University found a possible link between JAK inhibitor medication and unexpected blood clots. The researchers identified a potential mechanism behind the side effect, which could lead to the development of safer medications.
A new study suggests that hospital rehabilitation for older adults might only be the beginning of a longer journey. While therapy is crucial in mitigating functional decline, only a small minority of patients receiving intensive therapy (14+ hours/week) had a greater likelihood of home discharge.
Researchers have discovered a blood test that can identify patients with a sleep disorder who are most likely to develop Dementia with Lewy Bodies. The blood test analyzes two proteins in the blood associated with Alzheimer's disease and predicted dementia risk in almost 90% of patients, four years before symptoms appeared.
Researchers at the University of Missouri have identified a small molecule drug that targets a specific serotonin receptor, showing promise as a treatment for sarcopenia. The study suggests that this neurotherapeutic can improve muscle strength by activating motor neurons to fire more effectively.
Researchers have discovered a novel approach to protecting insulin-producing beta cells from glucolipotoxicity, a condition linked to type 2 diabetes progression. The findings could lead to promising treatments targeting beta cell dysfunction, potentially slowing or preventing disease progression.