Articles tagged with Cognitive Function
Researchers at Penn State found that weight fluctuations and changes can lead to faster cognitive decline in older adults. The study analyzed data from 4,304 participants and showed that those with greater variability in weight experienced more rapid cognitive declines.
A study published in Translational Psychiatry found that following a well-formulated ketogenic diet for at least 10 weeks resulted in a significant decrease in depression symptoms, improved global well-being, and enhanced cognitive performance among college students. The pilot trial showed a roughly 70% reduction in depression symptoms.
A new brainwave test developed at the University of Bath has been shown to detect signs of memory impairment linked to Alzheimer's disease years before clinical diagnosis. The Fastball EEG technology, a three-minute passive test, can reliably identify memory problems in people with Mild Cognitive Impairment.
Scientists Sharon Swanger and Shannon Farris study how mitochondria in vulnerable memory circuits become overloaded with calcium, contributing to early memory breakdowns. Their research aims to find early signs of stress or failure in the entorhinal cortex-hippocampus circuit.
Researchers found that faster biological aging is associated with lower scores on digital cognitive tests, particularly among older adults. DNA methylation patterns were used to estimate biological age acceleration, and protein markers PAI1 and ADM showed strong associations with lower cognitive scores.
Aging populations exhibit a positivity bias in recognizing emotions, associated with observable changes in brain linked to cognitive decline and neurodegeneration. The study correlates age-related positivity bias with poorer cognitive performance but not necessarily emotional decline.
Two brain regions have been identified as a neural compass, allowing people to maintain their sense of direction while navigating naturalistic virtual reality cities. These regions are consistent across different city features and task phases, suggesting they track direction relative to the north-south axis.
A new study by Tel Aviv University reveals that repeated exposure to an image, whether authentic or AI-generated, boosts its perceived credibility. This 'mere exposure effect' also applies to images created using artificial intelligence algorithms, raising concerns about the spread of false visual information on social media.
A new study by the Environmental influences on Child Health Outcomes (ECHO) Cohort suggests that higher vitamin D levels during pregnancy may be associated with better cognitive test scores in children. Children of Black mothers, in particular, showed strongest association between vitamin D and cognitive development.
Researchers used IntelliCage to assess spontaneous behavioral changes in a mouse model of schizophrenia, finding increased hyperactivity and exploratory behavior after treatment with MK-801. However, cognitive flexibility was impaired, suggesting schizophrenia-like behaviors.
A study published in Alzheimer's & Dementia found that regular opioid use is associated with a 20% increased risk of all-cause dementia and over 70% increased risk of dementia among those taking strong opioids. Regular opioid use was also linked to reduced brain volume, lower fluid intelligence, and higher risk of vascular dementia.
Researchers at Florida Atlantic University are using a genetically tractable model organism, C. elegans, to dissect the cellular pathways impacted by amphetamines. The study aims to identify novel regulators of dopamine release and genes that mediate amphetamine's effects independently of traditional dopamine mechanisms.
A randomized clinical trial found that SMART training improved cognitive gains in active-duty service members with mTBI, with significant benefits seen after just one-third of the training time compared to traditional SCORE protocols. The study suggests that SMART brain training can contribute to faster return to mission readiness and ...
A new study from the University of Southern California reveals that just 30 days of guided mindfulness meditation can significantly enhance key aspects of attentional control. The study demonstrates that even short-term meditation can lead to measurable cognitive improvements, particularly in reaction speed.
Research from Kyoto University found that continuing to play a musical instrument into old age preserves brain function and prevents atrophy in the putamen. Long-term practice showed no decline in verbal working memory performance or gray matter volume, while short-term practice improved memory function for four months.
Researchers at the University of Oklahoma investigate the overlap between cognitive decline caused by chemotherapy and aging, discovering decreased blood flow, disrupted blood-brain barriers, and senescent cells. Removing these cells with senolytics can improve cerebral blood flow, cognition, and overall brain health.
Scientists have discovered the structure and shape of key receptors in the cerebellum, a region critical for movement, balance, and cognition. This finding could lead to the development of therapies to repair damaged synapses and improve brain function.
A 16-year study of over 10,000 individuals aged 50+ found that those with higher wellbeing were more likely to have better scores on memory tests. The association was independent of depressive symptoms and suggested that psychological factors affect brain health.
A study of over 1,000 twins found that cognitive tests in infancy can predict adult intelligence and cognition, with environmental influences playing a significant role. Early life environments, including pre-preschool years, matter more than previously thought, suggesting potential interventions to support cognitive aging.
A new study found that remotely supervised exercise programs can significantly improve cognitive function in older adults with MCI. The research highlights the potential of home-based exercise interventions in preventing cognitive decline.
Using an algorithm called the Krakencoder, researchers at Weill Cornell Medicine mapped how the brain's anatomical connections and activity patterns relate to behavior. The tool accurately predicted individual's functional connectome about 20 times more than previous approaches, also mapping age, sex, and cognitive performance scores.
A cohort study of 4 countries found that both maternal and paternal higher education levels were linked to reduced cognitive decline, with own education mediating these associations. The study highlights the long-term impact of parental education on offspring cognitive health across diverse cultural contexts.
Researchers from The University of Osaka have demonstrated that vision transformers can spontaneously develop human-like visual attention patterns without specific training. This breakthrough showcases the potential of self-supervised learning for advancing AI applications and modeling biological vision.
A comprehensive analysis reveals how brains generalize learning from previous experiences to new scenarios, mapping neural pathways from hippocampus to cortex. The study's findings highlight the critical role of the hippocampus and prefrontal cortex in cognitive generalization.
Researchers mapped dynamic cellular mechanisms of memory formation, storage and update, revealing new insights into encoding experiences in the brain. Memories are stored through biophysical changes in neuronal ensembles, which can be manipulated to induce recall.
A new USC-led study found a significant link between type 2 diabetes and cortical thickness in older adults from various populations. The researchers discovered that individuals with T2DM exhibited thinner cortex, particularly in temporal and parietal regions critical for memory and cognitive function.
Preliminary research suggests that long working hours can induce neuroadaptive changes in the brain, particularly in areas associated with emotional regulation and executive function. The study found increased brain volumes in regions such as the middle frontal gyrus, which is involved in attention and problem-solving.
Researchers at the Center for Genomic Regulation discovered a nine-letter microexon in DAAM1 exclusively in neurons that is critical for neuronal development and memory. Deleting this microexon in mice resulted in reduced learning spines and impaired memory function, with animals remembering roughly 40% less in standard memory tasks.
Researchers developed MuSICCA, a music therapy tool that uses musical stimulation to assess levels of consciousness in children with brain injuries. The study found high agreement among participants that the tool is suitable for use with children, providing guidance for caregivers and supporting clinical teams.
A study found that satisfying intimate relationships and general social support can reduce cognitive problems experienced by breast cancer patients undergoing chemotherapy. The research suggests that couples therapy could be a helpful option for partnered patients, while oxytocin levels decreased significantly during treatment.
A University of Ottawa-led study reveals that serotonin neurons are connected and interact with each other, controlling serotonin release in specific regions of the brain. This complex system has implications for understanding decision-making and developing targeted therapeutics for mood disorders.
The World Sleep Society releases recommendations on wearable sleep trackers, providing clear guidelines for consumers, clinicians, researchers, and manufacturers. Key takeaways include choosing a device suitable for individual use cases and focusing on fundamental sleep measures rather than specific stages of sleep.
A new study from the University of Missouri suggests that exercise can improve brain health and mitigate cognitive decline, even when ketone production in the liver is impaired. The research found that endurance exercise can prevent cognitive impairment caused by compromised hepatic ketogenesis.
Severe permanent impairment in function and cognition are prevalent among long-term care residents nearing the end of life. A minority of residents live in these states for extended periods, suggesting the need for resident-centered medical decision-making.
Research found that adolescents who slept longer performed better at cognitive tests, with those sleeping 7-25 minutes more performing better. The study also found differences in brain volume and structure between the groups.
A recent study by researchers from the University of Tsukuba found that cognitively impaired older drivers are less likely to be involved in car-to-car crashes when accompanied by a passenger. The analysis revealed that second-party drivers were more likely to have been accompanied by a passenger than first-party drivers, regardless of...
Women who enter menopause before age 40 experience worse cognitive decline compared to those entering menopause after 50. This association may help clinicians assess patient risk of developing dementia. Further research is needed to understand the underlying mechanisms and design potential treatments.
MIT researchers have found that a computational model of the ventral stream, which processes object recognition, also performs well on spatial tasks such as determining an object's location and orientation. This challenges the dominant perspective that the ventral stream is optimized for object recognition.
Researchers found that SIRT2, a previously unknown enzyme, plays a key role in excessive GABA production associated with Alzheimer's disease. This process leads to brain inflammation and memory impairment. By targeting SIRT2, scientists can selectively block its harmful effects on memory without affecting other brain functions.
A comprehensive longitudinal analysis of obesity trajectories identified distinct patterns affecting brain morphology, function, and cognition in middle-aged and older adults. The study suggests sustained obesity accelerates brain aging, highlighting the clinical importance of long-term monitoring and management.
A new study by researchers at Tufts University suggests that a lack of vitamin K may increase inflammation and hamper proliferation of neural cells in the hippocampus, a key region for learning and memory. Vitamin K deficiency was also associated with increased neuroinflammation and reduced neurogenesis, leading to noticeable cognitive...
New research reveals changes in brain connectivity during chemotherapy in breast cancer patients, particularly in the frontal-limbic system and cerebellar cortex. These changes worsen as treatment continues, suggesting that chemotherapy can quickly disrupt brain function in breast cancer patients.
Professor Tatia Lee's award-winning paper reports a study showing Qigong improves processing speed, sustained attention, and hippocampal volume in healthy older adults. The results suggest that Qigong can benefit brain health through its effects on the immune system.
Researchers have discovered that the thalamus can update its own connections independently of the cortex, a finding relevant to children with neurodevelopmental disorders. This breakthrough suggests that modulating neurotransmitters in the thalamus could alter sensory processing and improve cognitive function.
Researchers found that immune molecule IL-17 influences brain regions to induce either anxiety in the amygdala or sociable behavior in the somatosensory cortex. This discovery highlights the interconnectedness of the immune and nervous systems.
The DAM-Decision and Memory group at Universitat Jaume I studied the cognitive and neural computations that guide decision-making and long-term memory. They found that the hippocampal and medial prefrontal cortex regions use context boundaries to make decisions in both spatial and abstract contexts.
A new study has revealed that Beagle dogs carrying mutations in the Shank3 gene exhibit face processing abnormalities, similar to those observed in human ASD patients. The research provides direct experimental evidence that mutations in Shank3 lead to ASD-like deficits in face processing, contributing to social impairments.
Rats exposed to high amounts of alcohol demonstrated poor decision-making during a complex task even after a monthslong withdrawal period. The team linked the behavioral difficulties to dramatic functional transformations in the dorsomedial striatum, a part of the brain critical for decision-making.
Patients prescribed medicinal cannabis in Australia showed long-term improvements in overall health-related quality of life, fatigue, and sleep disturbance. The study, which recruited over 2,300 participants, also found improvements in anxiety, depression, insomnia, and pain for those with corresponding conditions.
A new study published in Radiology found that higher blast exposure correlated with changes in brain function and structure, even when standard MRI exams appeared normal. The researchers discovered weaker connectivity in key areas and more severe symptoms such as memory problems and post-traumatic stress disorder.
Researchers used mice to examine the activity of two neuronal proteins linked to autism. They found that a natural balance between MDGA2 and BDNF maintains normal neuron activity, but disruption can lead to ASD-like symptoms. This study suggests MDGA2 and BDNF as promising therapeutic targets for future treatments.
A new study from USC Dornsife's Brain and Creativity Institute found that nostalgic music engages the brain's default mode network linked to memory and self-reflection, as well as its reward circuitry. This discovery could support emotional well-being and cognitive function in individuals with memory impairments.
Research at Maharishi International University found that long-term TM practitioners have lower inflammation, slower age-related decline in cognitive function, and reduced cortisol levels, indicating potential benefits for overall health and longevity. The study suggests a protective effect against both stress and aging.
Research published in JAMA Network Open found that college graduates experienced faster cognitive decline after a stroke compared to those with less education. The study highlights the importance of identifying patients at high risk for post-stroke cognitive decline to target future interventions.
A new digital 'translator' for brain studies enables researchers to map the brain in a standardized way, facilitating discoveries and treatments for various disorders. The open-source software allows for the comparison of brain imaging data with widely used brain atlases, promoting commonalities across findings.
Groundbreaking research from the University of South Australia shows that any form of exercise can significantly boost brain function and memory across children, adults, and older adults. Regular exercise improves general cognition, memory, and executive function in both healthy individuals and those with clinical conditions.
Researchers at ISTA discovered that neural activity patterns during sleep reflect recently learned spatial memories and transform into those seen later upon awakening. This 'representational drift' phenomenon optimizes memory representations for long-term storage, allowing the brain to free up resources for new memories.
Despite severe sleep deficits, insomniac fruit fly mutants exhibit enhanced memory performance through altered PKA signaling in the mushroom body. This finding suggests a complex relationship between sleep and memory functions.
Researchers developed a portable system using AI to spot cognitive impairment by measuring subtle differences in motor function. The device accurately identified 83% of participants with mild cognitive impairment (MCI), offering potential for early intervention and improved outcomes.
A new study suggests that hospital rehabilitation for older adults might only be the beginning of a longer journey. While therapy is crucial in mitigating functional decline, only a small minority of patients receiving intensive therapy (14+ hours/week) had a greater likelihood of home discharge.