Articles tagged with Human Physiology
Researchers at UCSF have identified 16 molecules in the blood that rise during menopause, associated with brain aging and Alzheimer's disease risk. Higher levels of these molecules in older women are linked to worse memory and thinking skills, as well as increased dementia risk.
A new Cochrane review suggests that personalized programs to prevent falls in older people may not be effective in reducing falls. The review found that multifactorial programs, which are tailored to individual risk, have little or no benefit in preventing falls compared to standard medical care, exercise, or falls prevention education.
A new Cochrane review has found that emergency contraception containing mifepristone is more effective than other common methods, such as levonorgestrel, with fewer side effects. Mifepristone also showed a lower risk of nausea and vomiting compared to other methods, but a higher likelihood of delayed menstruation.
Researchers analyzed data from the Framingham Heart Study to investigate the relationship between menopause and aortic stiffness. The study found that factors other than menopause timing contributed to the increase in pulse pressure in women after midlife.
Researchers found that meal timing programs the liver's daily rhythms and can have serious metabolic and health consequences when out of sync. The liver uses food signals to activate metabolic pathways, which can conflict with the body's natural circadian clock, leading to health issues.
A large UK study found that hormone replacement therapy (HRT) may reduce the risk of dementia, particularly for women who have undergone surgical menopause. The study, which followed over 180,000 postmenopausal women, found that HRT was associated with a 16% lower risk of developing Alzheimer's disease compared to non-users.
A $3.3 million NIH grant will support a five-year study on opioid treatment during breastfeeding, aiming to improve drug safety for lactating mothers. The researchers will develop a cell-based assay and use physiologically based pharmacokinetic models to predict drug levels in mothers and infants.
A Bar-Ilan University study reveals that directing attention toward bodily sensations reduces inflammation and accelerates recovery in healthy volunteers. The study found that nearly 90% of participants showed smaller inflammatory responses when focusing on the affected area, with faster return to baseline.
The USC Leonard Davis School of Gerontology has received a $7.5 million grant to establish GeroSCORE, a national hub for discovery and collaboration on sex differences in aging. The center will conduct innovative research, develop new tools and analytical methods, and serve as a resource for early-career investigators.
A new Cochrane review analyzed 11 studies involving 2,524 women undergoing embryo transfer, finding no reliable evidence that preparatory techniques improve IVF success rates. The techniques examined included straightening the utero-cervical angle and removing cervical mucus before transfer.
A recent WSU study suggests that working from home alone is not a sufficient condition for successful breastfeeding. The researchers analyzed the effects of working from home on breastfeeding outcomes and found no significant correlation between the two.
The review challenges common misconceptions about early milk production and breast pumps. It found that colostrum is sufficient for newborn needs and pacifier use does not interfere with breastfeeding. The study's findings suggest 'small changes' to support breastfeeding success in hospitals.
A recent study found that a higher body fat percentage is linked to lower sperm counts and changes in male reproductive hormones. Men with high body fat percentages had lower semen volume, sperm concentration, and testosterone levels compared to those with normal body fat percentages.
Researchers discovered a small mutation in the RBM20 protein leads to vastly different disorders in heart muscle cells. The study identified molecular targets for patient-specific therapies and potential new active substances.
A new study found that women with unmedicated depression may struggle to regulate body temperature in hot weather, but those taking SSRIs respond similarly to healthy individuals. The research suggests that SSRI treatment can help depressed women tolerate heat stress more effectively.
A new study found that prenatal oestrogen levels in mothers are positively related to their newborn's head circumference. The researchers also discovered that this influence is stronger for boys than girls, shedding light on the evolutionary drive for larger brains in humans.
Researchers at King's College London discovered that chewing sugary gum after consuming beetroot increases nitrite production, leading to lower blood pressure. This finding could have implications for sports people using beetroot to improve athletic performance.
A study of 211 million supermarket transactions found that 26.7% of customers who bought menstrual products also purchased pain relief, a trend linked to income level. The analysis highlights the need for greater awareness and policy interventions to address menstrual pain disparities.
A study found that 14 million workdays are lost annually due to menopause, while women rely on online misinformation for medical advice. The authors advocate for open conversation and inclusive approaches to combat stigma and support women's health during this transition.
A large study of nearly 40,000 women found that plant-based diets with lower insulinemic potential can help women manage their weight and reduce the risk of obesity during menopause. Women who followed a diet rich in whole grains, nuts, legumes, and vegetables had a significantly lower risk of developing obesity.
Researchers have created a new scale to measure whether lactating mothers' psychological needs are being met, providing a tool to improve breastfeeding outcomes. The study found that when all three basic needs (autonomy, competence, and relatedness) are satisfied, exclusive breastfeeding is more likely to persist.
A study by the University of Cambridge found that racism and socioeconomic stress can alter key physiological processes in the body during pregnancy, leading to higher rates of preeclampsia and preterm birth in black women. These changes are not due to genetic differences but rather persistent socio-environmental stressors.
A new international study by Adelaide University researchers found that genetics influence how lifestyle-behavioural factors impact ageing. Healthier ageing is associated with greater physical activity, better diet, and higher educational attainment, while smoking and suboptimal sleep duration have negative effects.
A new study from Tulane University found that women with high predicted cardiovascular risk face nearly double the risk of hip fracture. The association was stronger in women under 65, and higher cardiovascular risk was linked to fractures in weakened bones in major areas.
Researchers found that penguins living in zoos with regular food access and limited physical activity age faster, but live longer than those in the wild. The study reveals a link between zoo conditions and accelerated aging mechanisms.
Researchers found that people following a Mediterranean-style diet have higher levels of humanin and SHMOOSE, which are linked to protection against cardiovascular disease and neurodegeneration. The study suggests that specific components of the Mediterranean diet may directly influence mitochondrial biology.
Researchers from the University of Kansas used motion capture technology to analyze shooting mechanics, finding that greater flexibility in the preparatory phase is crucial for accuracy. The study's findings will be used to attempt a new world record for most consecutive made three-point shots.
A new study shows that high-intensity interval training increases the number of mitochondria and expands the active membrane, enhancing energy production and potentially improving endurance. The findings, published in the University of Southern Denmark, also suggest that muscle mitochondria are more adaptable than previously thought.
Researchers found that an approved antifibrotic drug, finerenone, can reduce ovarian fibrosis and promote follicle growth in women with premature ovarian insufficiency. Clinical trials showed that finerenone improved follicle development and mature oocyte quality in women with POI.
A new study by engineers at the University of Colorado Boulder found that dopamine influences movement speed, particularly when rewards are expected. The researchers discovered that people tend to move faster towards targets that offer rewards and experience a surge in energy when they receive unexpected treats.
A comprehensive study of collagen supplements found benefits in skin elasticity, hydration, and osteoarthritis symptoms. However, there were no meaningful improvements in sports performance or muscle recovery, dispelling some myths surrounding its use.
The Alliance for Clinical Trials in Oncology will host a webinar highlighting recent clinical advances in breast cancer, multiple myeloma, and leukemia. Researchers will present key findings from ASH and SABCS meetings, impacting treatment outcomes.
A new study from Duke University Medical Center suggests that a simple blood test can accurately predict short-term survival in older adults by detecting specific piRNA molecules. Lower levels of these molecules are linked to longer survival, echoing patterns seen in simple organisms where reducing them can extend lifespan.
A group of nerve cells in the brainstem has been identified as a stabilizing system for blood pressure, preventing fluctuations between daily activities. The study suggests that loss or dysfunction of these cells can lead to unstable blood pressure and is associated with conditions such as multiple system atrophy.
Researchers at King's College London discovered that loose fabric can predict body movements with 40% more accuracy than traditional sensors. This breakthrough has potential to revolutionize personal health devices, robotics research, and medical research on conditions like Parkinson's.
A new global study finds that physical inactivity is a significant driver of diabetes complications, with up to 10% of cases potentially preventable. The research emphasizes the need for tailored approaches to promote physical activity among people with diabetes, particularly addressing social and gender inequalities.
A new study found that strength training is the most effective tool for achieving 'high-quality' weight loss, reducing body fat while preserving and even increasing muscle mass. This type of exercise also reduces waist circumference, a key indicator of abdominal obesity and cardiometabolic risk.
A study published in Scientific Reports found that football fans' mean stress level was 41% higher on the day of a major match compared to non-match days. Participants experienced increased heart rates, peaking during the match, and were more likely to engage in risky behaviors such as drinking alcohol.
A new study from the University of Victoria found that higher insulin levels at age 47 predicted younger onsets of hot flashes and night sweats. Insulin may be a stronger predictor of hot flashes when taking other metabolic variables into account, while body mass index (BMI) appeared more closely associated with estrogen level changes.
Researchers from the University of Kansas discovered that taller, leaner athletes with improved jumping ability generate faster club head speeds. The study developed golf-specific load velocity profiles to help athletes and coaches develop plans for improvement, focusing on exercises like squats and building lean mass.
A study published in PLOS Biology found that males rate computer-generated figures with a larger penis as more intimidating and sexually competitive. Women also prefer taller, more V-shaped males with a larger penis, but beyond a certain point, further increases in size have diminishing benefits.
A new study published in Maturitas found that high-intensity interval training (HIIT) is the most effective exercise type for reducing body fat and maintaining muscle mass in seniors. HIIT involved short bursts of intense exercise followed by easier recovery periods, which helped retain lean muscle mass.
A preclinical study shows that cannabidiol restores emotional behavior, reduces alcohol-related vulnerability, and reverses gut microbiota alterations caused by prenatal alcohol exposure. Female mice particularly benefited from CBD treatment, which normalized their emotional alterations and eliminated vulnerability to alcohol addiction.
Researchers identified cilia-mediated Hedgehog signaling as a key regulator of tooth development. The study found that disrupting Cilk1 levels can lead to stepwise changes in tooth formation and morphology, including extra teeth or fused molars. This discovery may support earlier diagnosis for children with ciliopathies.
Researchers have identified an effective strategy to reduce structural liver damage and improve hepatic vascular function in cirrhosis. Blocking the PAF-R receptor can help rebalance immune and inflammatory responses within the liver.
A novel analysis found that financial strain and food insecurity accelerate biological aging and increase mortality risk, surpassing traditional risk factors. The study emphasizes the need for targeted preventive interventions and patient-centered care to address social determinants of health.
Researchers found that the skin relies on TRPM8 sensor for cold detection, while internal organs primarily use TRPA1 sensor. This difference explains variations in external and internal cold perception, and has implications for understanding thermal homeostasis and pathologies related to cold sensitivity.
A new study found menopause symptoms are frequently reported by female endurance athletes, with 88% experiencing sleep problems and 83% feeling physical and mental exhaustion. These symptoms negatively affect training and performance, particularly musculoskeletal changes and quality of life.
Research finds that standard road crossing intervals are too short for older adults with limited mobility, resulting in a need for slower crossings. The study analyzed walking speeds of 1,110 adults aged 65 and over and found that just 1.5% can cross the road within the typical time allowed by pedestrian signals.
A study of 349 new parents found intrusive thoughts and psychotic-like experiences more prevalent than thought, causing severe distress linked to higher parenting stress and lower satisfaction. The research highlights the need for normalisation, stigma reduction, and targeted support for affected parents.
Researchers at Florida Atlantic University have discovered a potential new treatment for Alzheimer's disease by targeting muscle protein Cathepsin B. The study found that increasing Ctsb in muscle tissue may offer protection against the effects of AD and promote brain cell growth, restoring protein balance and rebalancing brain activity.
Researchers at ETH Zurich have successfully produced muscle tissue using a new biofabrication system called G-FLight in microgravity. The process enables rapid production of viable muscle constructs with similar cell viability and muscle fibers as those printed under gravity.
A recent study from Harvard John A. Paulson School of Engineering and Applied Sciences uses wearable sensor technology and machine learning to estimate ground-reaction forces in runners. This data can provide insights into performance and injury, enabling the development of devices that deliver real-time feedback to users.
Research from UC Riverside found that fit mice increased voluntary running activity when deprived of water. The study suggests that physical fitness may provide a physiological buffer against dehydration, which could be beneficial for humans in a warming world and individuals working in physically demanding outdoor occupations.
A new Cochrane review found that immediate skin-to-skin contact between newborns and their mothers significantly improves exclusive breastfeeding rates, optimal body temperature, breathing, and heart rate. The review suggests that skin-to-skin contact should be the global standard of care for all babies after birth.
A new study from the University of Kansas found that football practices can be up to 40% more physically demanding than games, with defensive backs running farther distances. The research used GPS technology to measure training loads and provide insights for coaches and trainers to design optimal practice schedules.
A new study has identified a leptin-sensitive brain circuit in the lateral hypothalamus that helps animals overcome anxiety to perform essential behaviors such as eating, exploring, and limiting maladaptive hyperactivity. Boosting the activity of these neurons can restore adaptive choices even under conditions that cause anxiety.
Researchers found that even extreme athletes cannot surpass an average metabolic ceiling of 2.5 times their basal metabolic rate in energy expenditure. The study tracked ultra-runners and cyclists, finding that while they can burn six to seven times their BMR during multi-day races, longer periods see a return to the predicted ceiling.
Researchers from the University of Osaka have identified a crucial protein, TMEM217, that regulates sperm movement. By restoring the signal, they successfully treated immotile sperm and enabled them to fertilize eggs in vitro, leading to healthy births.
A new study led by MSU researchers explores the link between hormonal fluctuations during midlife and mental health outcomes like psychosis. The comprehensive study, funded by the National Institute of Mental Health, aims to identify women at risk and develop personalized treatments.