Articles tagged with Brain Activity Maps
Researchers at Cold Spring Harbor Laboratory created the first cross-species brain map to link mouse and marmoset regions. The study found that 43% of mouse brain regions match with marmoset regions, shedding light on human brain function and potential disease insights.
A study published in Molecular Psychiatry found that about 65% of patients who developed psychosis after age 40 showed abnormal tau buildup, compared to 15% of healthy older controls. The findings suggest diverse tau-related brain changes may be involved in late-onset psychosis.
Researchers at Texas A&M University have found a way to intervene early in traumatic brain injuries using a natural, gut-derived chemical that prevents post-traumatic epilepsy from taking root. The treatment reduced brain inflammation, improved memory and mood, protected brain cells, made seizures both rarer and harder to trigger.
Researchers study blind Mexican cavefish to understand how evolution rewires the brain and shapes behavior. They found that cavefish become more active in light, a response believed to help them avoid predators.
Scientists have discovered a new type of brain wave that rotates over space and time, relying on a circular anatomical circuit in the sensory cortex. This rotation is coordinated between different brain regions, including sensory and motor parts, and may play a role in sharing information across these areas.
Researchers have developed a digital brain twin using multimodal data, providing anatomically accurate brain models that can be used in experimental and clinical settings. The models were reconstructed simultaneously with brain anatomy and dynamics from neural data.
Researchers linked duration and severity of depression to differences in functional brain connections, paving the way for personalized treatments. Changes in brain networks, particularly the Central Executive Network and Default Mode Network, were associated with varying degrees of depressive symptoms.
A longitudinal study identified distinct brain-wave patterns emerging from age 9 that can forecast a child's vulnerability to anxiety or depression by age 13. The predictive markers reveal divergent neurodevelopmental trajectories linked to the right and left sides of the brain, respectively.
A new study at Florida Atlantic University maps the neural wiring system linked to a fly's split-second escape behaviors, revealing a decentralized communication strategy. The findings provide insight into how brains process information at extraordinary speed and may represent a conserved blueprint shared across species.
Researchers found that psilocybin causes temporary shifts in brain entropy, leading to increased insight and emotional self-awareness. This correlates with improved well-being and cognitive flexibility, suggesting the psychedelic trip is key to its therapeutic effects.
Genomic Press launches Brain Health, a new peer-reviewed journal dedicated to the science of lifelong brain resilience, featuring research on glial plasticity and recovery from depression. The inaugural issue explores the intersection of fields including cognitive reserve, sleep, aging biology, nutritional psychiatry, and social sciences.
The Individual Brain Charting project has released its fifth update with a new set of cognitive tasks, expanding the dataset to 40 hours of scanned data per participant. This provides an exceptionally rich resource for studying individual variability in brain organisation and understanding brain function.
Neurobiologists have identified the brain circuitry responsible for placebo pain relief, revealing a site where endogenous opioid peptides drive pain relief. The study offers hope for using expectancy-driven placebo effects as a substitute for painkillers and developing protocols to produce placebo pain resilience in humans.
A secondary analysis of the ANGEL-ASPECT trial found EVT to be beneficial for patients with anterior-circulation LVO and a large ischemic core and absent-to-moderate white matter lesions. In contrast, those with severe WMLs showed less pronounced benefits, suggesting uncertainty about EVT's efficacy in this subgroup.
A research team identified distinct subregions within the default mode network (DMN) that act as senders and receivers of information, enabling flexible shifts between perception and memory-driven thought. The study reveals that the DMN is not functionally uniform but composed of subregions with distinct connectivity biases.
A Northwestern University study found that imagination is not just a copy of sensation, but emerges at later stages of processing when the brain represents information holistically. The researchers mapped brain activity during imagination and perception, finding overlap in higher-level association areas.
A Tulane University study reveals how the brain regulates defensive behavior and fine-tunes fear responses as perceived threats diminish. Researchers identified distinct roles for neurons in the central amygdala, which help determine whether an animal responds with intense escape behavior or freezing.
Researchers used diffusion MRI to study the brains of seals, sea lions, and coyotes, finding a 'brain bypass' that allows for vocal flexibility. This discovery may hold the key to understanding the evolution of human language.
Researchers from Mass General Brigham have identified a neural circuit linking prior experiences with current aversions and preferences when it comes to dining choices. The findings suggest that dysfunction in this brain circuit could be a factor in disordered eating and obesity, providing new potential targets for treatment.
Researchers have uncovered a new understanding of how cardiac events are interconnected with the brain and nervous/immune systems. They found that sensory neurons in the vagus nerve detect injury and transfer signals to dedicated brain structures, leading to activation of the immune system.
Researchers at the University of Notre Dame investigated how brain networks are organized and work together to form a unified system. They found evidence for system-wide coordination in the brain that is both robust and adaptable, suggesting that intelligence reflects how brain networks are coordinated and dynamically reconfigured.
Researchers at Karolinska Institutet created the first activity-based maps of the prefrontal cortex, revealing a hierarchy of information flow rather than tissue structure. This challenges traditional definitions of brain regions and has major implications for understanding brain organisation overall.
Researchers found that early communication between three pairs of brain regions is associated with favorable six-month functional outcomes. The study identified signature patterns in resting-state functional MRI data that can strengthen standard prognostic methods for assessing outcomes after moderate-to-severe brain injury.
A mouse study by Okinawa Institute of Science and Technology researchers has found that acetylcholine release is essential for breaking habits and enabling new choices to be made. The study's findings may help understand diseases such as Parkinson's disease, addiction, and obsessive-compulsive disorder.
Researchers at Brown University have created a bioluminescence tool that enables the measurement of activity in living brain cells without damaging them. The CaBLAM tool uses bioluminescent light production to capture single-cell and subcellular activity at high speeds, allowing for longer recordings and reducing hardware requirements.
The EBRAINS Summit 2025 will bring together experts to assess how neuroscience can drive medical progress, digital innovation, and responsible data use. Preliminary results from the EPINOV clinical trial, integrating virtual brain technology for epilepsy surgery planning, will be presented.
A new study found that individuals with a history of major depression showed higher MRI markers associated with neuroinflammation in the VTA, suggesting increased extracellular inflammatory processes. Current depressive symptom severity was associated with distinct microstructural changes indicating different underlying pathophysiologi...
Researchers developed a novel method called cytoarchitecture-based link estimation (CABLE) to infer axonal pathways from routine histology, reconstructing three-dimensional whole-brain fiber tracts at cellular scale. CABLE outperforms existing neuroimaging tools in resolving complex geometries and has potential applications in psychiat...
A new study by Carnegie Mellon University's Wood Neuro Research Group uses advanced brain imaging and a digital visualization tool to better understand how pain is processed in the brain for people with sickle cell disease. The team found that patients had reduced connectivity across key brain networks linked to pain perception, partic...
Researchers used data from the Human Connectome Project to build computational models that linked connectivity with brain activation across various cognitive processes. The findings show a consistent correlation between connectivity and function, suggesting that specific patterns of connectivity can predict brain activity.
A new study by New York University researchers found that the brain processes multiple words at once in a hierarchical manner, similar to a subway system. The brain coordinates different levels of processing, such as sounds, words, and meanings, without interference, allowing for efficient interpretation of speech.
A study from the Norwegian University of Science and Technology found that older people tend to interpret ambiguous facial expressions as positive. The researchers discovered that this is due to adaptations in the locus coeruleus, a small organ at the bottom of the brain responsible for regulating alertness and attention.
The Neuropixels Ultra probe overcomes technical challenges in recording individual cells across multiple brain regions. It detects twice as many brain cells and distinguishes specific subtypes, enabling scientists to decode and track brain cell performance related to visual stimuli.
Researchers developed a fiber-optic method to track Alzheimer's plaques in freely behaving mice, allowing for real-time monitoring and long-term tracking of pathological changes. The technique uses fluorescent dye to bind specifically to amyloid fibrils and provides a minimally invasive way to study disease progression.
A new study published in Biological Psychiatry found that individuals with similar levels of autistic traits are more attracted to each other and their brains synchronize in unique ways during passive and active communication. This suggests a novel approach for building social connection among people with autism by tailoring environments.
Researchers developed a new method to correct for variations in brain imaging measurements, reducing bias and increasing the accuracy of studies on ADHD. The traveling-subject method demonstrated reduced measurement bias while maintaining sampling bias, revealing decreased brain volume in critical regions for cognitive functions.
Researchers found that brain maps of the hand and lips remained consistent even after amputation, contradicting previous views of reorganization. This study has implications for treating phantom limb pain and controlling robotic replacement limbs via neural interfaces.
A new study found that tolcapone increases activity in the prefrontal cortex during self-control tasks, associated with better behavioral control and reduced alcohol consumption. The findings suggest that medications increasing prefrontal dopamine could be a promising lead for treating alcohol use disorder.
Researchers from FAU and the Sensing Institute created a detailed computer model of the mouse brain's vasculature, simulating how brain blood vessels respond to hemodynamics and vasodynamics. The model shows that transitional vessels play a critical role in regulating flow and protecting the brain during increased activity.
Young adults with higher genetic risk for depression show reduced brain activity in response to rewards and punishments, while sex-dependent neural responses were also observed. This study highlights potential early indicators for depression before symptoms fully manifest.
Researchers found that map-making brain cells in the hippocampus are activated differently even when navigating a static environment, shedding light on how the brain processes spatial memories. The study's findings could have profound implications for understanding memory, learning, and aging.
A study published in Scientific Reports found that 44% of autistic teens can mask their diagnosis in school settings, showing faster brain responses to faces and reduced emotional reactivity. Researchers hope this discovery will lead to better support for these teens.
The brain segments and organizes events into experiences by placing unique bookmarks on them, allowing us to revisit and learn from our lives. The lateral entorhinal cortex creates a signal that constantly drifts in a pattern never repeating itself, marking the beginning and end of an experience.
A novel study in Biological Psychiatry highlights the layered and complex interactions between clinical symptoms and neurobiological sources of variation in depression. The research found that multiple brain profiles may manifest as the same clinical symptoms, supporting the presence of both one-to-one and many-to-one heterogeneity.
A new study published in Neuron has identified a brain region, the fusiform gyrus, as key to distinguishing between real and imagined experiences. The region's strength of activity can predict whether someone judges an experience as real or imagined.
Researchers at Aarhus University and University of Oxford used a novel neuroimaging method to show that the brain dynamically reconfigures its organization in response to auditory stimulation. This discovery opens new possibilities for studying brain responses to music, consciousness, and other phenomena.
A recent study found that caffeine increases brain signal complexity and enhances criticality during sleep, with effects more pronounced in young adults. This can lead to a state where the brain is neither fully awake nor relaxed, potentially interfering with restful recovery.
A study found that connections between visual and language processing regions in the brain influence object knowledge. Stroke patients' brains showed stronger connections meant better performance on color-identification tasks.
Researchers have used AI and brain activity to study the Other-Race-Effect (ORE), a phenomenon where people recognize faces of their own race more easily than others. They found that faces from other races are processed more generally and with less detail, leading to less accurate recognition.
The DAM-Decision and Memory group at Universitat Jaume I studied the cognitive and neural computations that guide decision-making and long-term memory. They found that the hippocampal and medial prefrontal cortex regions use context boundaries to make decisions in both spatial and abstract contexts.
This study found that low-intensity multitask exercise increased delta power during sleep and activated the prefrontal cortex immediately after the session. The findings suggest that multitasking exercise may be a promising strategy for promoting better sleep in older adults.
Researchers developed DeepCeres, a software that uses AI tools to measure 27 structures of the cerebellum with improved precision. This will help in studying neurological pathologies such as ALS, schizophrenia, and Alzheimer's diseases.
Researchers discovered a common cognitive feedback loop used by Buddhist jhāna meditation and Christian speaking in tongues practices to achieve profound focus and joy. This 'Attention, Arousal and Release Spiral' offers insights into cultivating deep states of tranquility and bliss.
Researchers from Michigan State University used brain-scanning tools to predict visitation patterns in urban environments. The study found that the brain's reward system can shape human behavior within cities, aiding in designing sustainable living spaces.
A Princeton-led research team has built the first neuron-by-neuron and synapse-by-synapse roadmap through the brain of an adult fruit fly. The map reveals connections within the brain at every scale, enabling researchers to better understand its underlying logic and potentially develop tailored treatments for brain diseases.
A new study published in Frontiers in Behavioral Neuroscience has found that fans of action films and comedies react strongly to negative emotional stimuli, while those who prefer documentaries or crime films show a weaker reaction. The research suggests that people choose film genres that optimally stimulate their brains.
A study in Current Biology mapped a brain circuit responsible for detecting threats and forming fear memories. The hippocampus and subiculum are key structures involved, with the subiculum transferring information to the hypothalamus.
Researchers have discovered a new type of brain cell in the medial entorhinal cortex that accurately predicts future locations as an animal travels. This discovery helps explain how planned spatial navigation is possible and has important implications for understanding mechanisms of spatial navigation and episodic memory formation.
The UNLV study found that brain activity patterns change with the number of experiences, not time, and that increasing speed affects perception. The research suggests that our brains register a 'vibe' about time, making it faster when we're having fun or doing tasks efficiently.
Researchers used advanced brain imaging techniques to identify key regions and networks involved in creative thinking. The Default Mode Network (DMN) was found to play a crucial role, with activity originating from the DMN before being evaluated by other brain regions.