Articles tagged with Lipids
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
The 2016 ASBMB meeting featured scientific symposia on various topics including bioinorganic catalysis, cell signaling, chemical biology, chromatin organization, DNA replication, education, and glycoscience. Key researchers like Aziz Sancar will present their work on DNA repair and precision medicine.
A UCR team adapted CRISPR-Cas9 for use in Yarrowia lipolytica, a yeast strain that converts sugars into useful lipids and hydrocarbons. This breakthrough enables the production of new biofuels, specialty polymers, adhesives, and fragrances from cheap raw materials.
Researchers at SLU are developing a biomarker to help diagnose sepsis early and improve treatment outcomes. Chlorinated lipids may hold the key to this discovery, as they appear under conditions of inflammation.
Researchers at Ohio State University discovered a key molecule that enables cancer cells to produce lipids, leading to rapid tumor growth. Blocking this molecule may slow tumor growth and provide new therapeutic strategies for glioblastoma and other cancers.
Research reveals that tiny plankton can store large amounts of CO2, potentially doubling estimates of ocean carbon absorption. The copepod lipid pump mechanism is a significant discovery, as it was not previously considered in climate models.
Researchers found a new biomarker in ceramides that may help diagnose and treat episodic migraine. Women with episodic migraine had lower levels of ceramides in their blood compared to those without headaches.
Scientists at Kyoto University developed an approach to assemble DNA origami units into larger structures by using a double layer of lipids. This method allows for more freedom of movement and interaction between origami structures, enabling them to form nanomachines such as nanomotors for targeted drug delivery
Researchers found fossilized microbes in ancient rock samples from the Iberian continental margin, confirming a long-standing hypothesis that interactions between mantle rocks and seawater can create conditions for life. The discovery provides important insights into the possibility of 'intraterrestrial' life in rocks below the seafloor.
Researchers identify two transcription factors that regulate lipid accumulation in stressed algae, enabling sustainable fuels production. The study also demonstrates a strategy for overexpressing PSR1 to trick cells into producing lipids without dying.
Researchers at UT Southwestern Medical Center found that introducing an enzyme called ceramidase in diabetic mice rapidly improved insulin sensitivity. The study suggests a new means to potentially treat Type 2 diabetes and nonalcoholic fatty liver disease by lowering ceramide levels, which interfere with insulin signaling.
Researchers found that KLF15 helps maintain metabolic balance by controlling the availability of nutrients in the body. The discovery may also contribute to understanding diseases characterized by excessive bile acid production.
WSU scientists demonstrate that resveratrol converts excess white fat into beige fat, reducing weight gain by 40%. Polyphenols found in fruit enhance fat oxidation, preventing obesity and metabolic dysfunction. Increasing fruit consumption can boost total polyphenolic intake.
Research from Purdue University found that adding eggs to a salad with raw vegetables significantly improves the absorption of carotenoids. This is due to the lipid content in whole eggs, which enhances the absorption of these fat-soluble nutrients.
A 1500-year-old male skeleton from Great Chesterford in Essex, England, has been confirmed to have had leprosy through DNA testing and biomarkers. The leprosy strain originated from southern Scandinavia and dates back to the 5th or 6th centuries AD.
Researchers at Hamburg University of Technology, DESY, and Nestle found that reducing porosity, storing products at ideal temperatures, and controlling crystallization can help minimize fat bloom. This study provides new insights into the formation of fat bloom, an issue affecting millions in the food industry.
Researchers discovered that lipids in chocolate products move through pores and cracks, softening and dissolving solid cocoa butter into liquid form. By reducing pore number and liquid cocoa butter content, chocolatiers can minimize the formation of blooming coatings.
Yeonhwa Park's significant contributions to bioactive lipids have led to discoveries of CLA's role in reducing body fat and improving bone mass. Her research also explores the interaction between CLA and muscle, revealing improved exercise outcomes.
Researchers have discovered a new class of potentially therapeutic lipids, FAHFAs, which are found at lower levels in people with insulin resistance. Administering FAHFAs to diabetic mice improved glucose metabolism and insulin secretion, suggesting a potential avenue for developing novel medications.
Researchers developed a new yeast strain that can produce lipids at a higher rate, making it a viable platform for turning sugar into biofuels. The strain can also be used to produce oleochemicals, chemicals traditionally derived from plant and animal fats and petroleum.
A recent study found that pigs fed diets containing corn-ethanol co-products, such as distillers dried grains with solubles (DDGS), had no significant differences in growth performance compared to those fed a traditional corn-soybean meal diet. The study showed that conventional, high-protein, or uncooked DDGS can be safely included at...
Researchers at Ludwig Maximilians University have identified a novel chloroplast membrane protein that plays a central role in transporting fatty acids from chloroplasts into the cell cytoplasm. This discovery may lead to new strategies for producing biofuels, which are rich in TAG-rich plant oils.
Researchers have discovered a new mechanism by which immune cells in the skin function as the body's 'border control'. This finding could improve how we fight some infections, allergies and auto-immune diseases. The discovery of CD1a molecule reveals how it interacts with lipid molecules to identify foreign invaders.
Researchers found lipid droplet accumulation in glial cells before signs of neurodegeneration appeared, leading to impaired support for neurons. Reducing components of the pathway can delay neurodegeneration.
A new study found that protein Maf1 controls fat levels in C. elegans worms, suggesting a similar function in humans. Increasing or decreasing Maf1 levels resulted in significant changes in stored lipids.
Researchers have described the intricate relationships within a biological wastewater treatment plant in unprecedented detail. This study provides new insights into the laws governing bacterial function, with potential applications in medicine and environmental conservation.
The study reveals the complex relationships within a model ecosystem, with implications for protecting the environment and human health. The researchers found that Microthrix parvicella, a generalist bacterium, can adapt to various living conditions and dominate the wastewater treatment plant ecosystem.
A new study found that contact lens discomfort is associated with degradation of the lipid layer in the tear film. Applying a liposomal eyelid spray increased stability of the tear film and improved dry eye symptoms, suggesting potential benefits for patients with contact lens discomfort.
Researchers discovered that excess lipids in the lungs trigger an inflammatory response, leading to scarring and pulmonary fibrosis. The team's findings suggest a new direction for developing novel therapies by targeting lipid handling in the lungs.
Researchers have identified a new class of lipid molecules that enhance insulin sensitivity and blood sugar control, offering a promising direction for preventing and treating type 2 diabetes. The fatty acid hydroxyl fatty acids (FAHFAs) are produced and broken down inside the human body and may serve as an early marker for the risk of...
Researchers from Clemson University have discovered that lipids play a crucial role in the adhesion mechanism of barnacle cyprid larvae, paving the way for novel anti-fouling paint for ships and boats. The findings also provide insight into the development of new bio-adhesives for medical and industrial applications.
Researchers at the University of Bristol have developed a new strategy for disconnecting molecules, which could be used to create a tuberculosis (TB) vaccine. The method, described in Nature Chemistry, enables the synthesis of complex lipids like hydroxyphthioceranic acid in just 14 steps.
Researchers discover that P. gingivalis modifies its lipid A structure to evade host defenses and establish chronic infection, leading to persistent systemic low-grade inflammation. This mechanism contributes to the progression of atherosclerosis in blood vessels.
Researchers recommend considering additional factors that can affect microbial growth apart from lipids in parenteral nutrition. These factors include glucose concentration, proportion of glucose to lipid, and osmolarity.
Researchers identify a novel mode of cancer cell recognition by the immune system, opening up new possibilities for leukemia immunotherapy. A specific group of immune cells, called mLPA-specific T-cells, recognize and destroy leukemia cells triggered by the newly identified lipids.
A new study by Prof. Gennaro De Libero and his team at the University of Basel identifies a lipid molecule, methyl-lysophosphatidic acid (mLPA), that stimulates specific T cells to kill leukemia cells. This breakthrough discovery offers new avenues for non-invasive cancer immunotherapies.
Research reveals that lipid droplets play a crucial role in regulating histone proteins in fruit fly embryos, helping to maintain the 'perfect' balance required for development. The findings suggest that manipulating this process could potentially treat diseases linked to chromosome malfunction.
Goldenrod gall fly larvae produce a novel class of lipids that remain fluid at low temperatures, allowing them to survive freezing winters. These acetylated triacylglycerols are less energy dense than standard lipids and have antifreeze characteristics.
Researchers found that European humans have a higher number of Neanderthal variants in genes related to lipid breakdown, which may have provided a selective advantage. This study suggests that Neanderthal ancestry has driven evolutionary changes in lipid processing and brain composition among Europeans.
Researchers have discovered a blood test that can predict cognitive decline and Alzheimer's disease within three years with greater than 90 percent accuracy. The test identifies 10 lipids in the blood, which appear to reveal the breakdown of neural cell membranes in participants who develop symptoms.
A new study found that carotid artery MRI can accurately predict future cardiovascular events, including strokes and heart attacks, in people without a history of cardiovascular disease. The presence of a lipid core in the internal carotid artery was significantly associated with an increased risk of subsequent events.
Researchers developed a new source of renewable energy by genetically engineering yeast cells to produce lipids that can be used in place of petroleum-derived products. The platform produces the highest concentration of oils and fats reported through fermentation, enabling up to 90% of cell mass to become lipids.
Researchers at Dartmouth College have developed a new fluorescent compound to detect and measure cardiolipin, a unique lipid in cell membranes. The new dye, TTAPE-Me, improves upon existing methods for detecting cardiolipin, which is linked to various diseases including heart conditions, neurodegenerative disorders, and cancers.
A retrospective analysis of inpatients found that hyperhomocysteinemia and abnormal blood lipids exert synergistic effects on the onset of stroke. Patients with elevated homocysteine levels and abnormal blood lipids are predisposed to stroke, highlighting the importance of managing both conditions.
Artificial cells manufactured via microprinting can mimic natural cell membranes, allowing researchers to study cellular processes. The creation of uniform-sized artificial cells with proteins and lipids enables high-throughput screenings for drug delivery and disease prevention.
Researchers at Scripps Institution of Oceanography have developed a method to genetically engineer marine algae to produce more lipids, the fat molecules that store energy for fuel. This breakthrough enhances biofuel production and has the potential to lower costs and increase efficiency.
Researchers at Scripps Florida Institute have developed a highly programmable platform for creating synthetic cellular structures with complex membrane compositions. The approach enables the assembly of multi-layered membranes resembling the cell nucleus envelope, offering new insights into biological function and evolution.
Mayo Clinic researchers have discovered a genetic mutation that alters lipid metabolism in Parkinson's patients, leading to higher levels of ceramides and glucosylceramides in the blood. This biomarker is associated with severe cognitive impairment and dementia in Parkinson's disease.
Researchers developed a method to extract and analyze lipid-soluble metabolites from human mesenchymal stem cells using MRI spectroscopy. The technique provides valuable insights into the metabolic characteristics of MSCs, which is essential for optimizing detection efficiency while minimizing cell usage.
A study by Purdue University researchers found that pigs thrive on lipids from soybean oil, leading to improved growth performance. The study's results suggest that using concentrated energy sources like soybean oil can help counteract issues limiting growth in nursery pigs.
Researchers mapped how critical molecules regulate inflammation during flu infection, discovering new targets for therapies. The study provided a holistic view of the host-pathogen interaction, revealing lipid mediators' dual role in controlling inflammation.
A new strain of algae discovered in Colorado's Rocky Mountains has been found to grow at temperatures approaching freezing and accumulate large intracellular stores of lipids. The algae produces the highest quantity of lipids when grown under high light and low temperatures, making it an ideal source for biofuel production.
Researchers create nanoparticles using natural lipids derived from grapefruit, which can transport therapeutic agents to specific cells without causing adverse effects. The technology has been validated in a Phase 1 clinical trial for colon cancer patients and may be applied to treat inflammation-related autoimmune diseases.
Despite concerns over high vitamin E intake, a new review concludes that the body can eliminate excess levels of the vitamin, making it impossible to take a harmful amount. Vitamin E is essential for proper organ function and has antioxidant properties.
Researchers have developed a new method called CLARITY that allows for the analysis of brain tissue in its entirety, preserving its 3D structure and integrity. This breakthrough method enables scientists to study the brain's finer workings, including cells and molecules, without losing larger-scale circuit perspective.
Researchers at Stanford University have developed a process called CLARITY that renders mouse brains transparent, enabling 3D imaging and molecular analysis. This breakthrough technology allows scientists to study the brain's complex structures without sectioning or damaging the tissue.
A study using neutrons has explained how ozone causes severe respiratory problems by attacking the fatty lining of lungs. The attack leads to increased surface tension, impairing oxygen and carbon dioxide exchange.
Studies show that reducing salt intake lowers blood pressure, reduces the risk of stroke and heart disease. Increasing potassium intake also has significant health benefits, with reduced blood pressure and a lower risk of stroke in adults. Lowering sodium intake should be part of public health efforts to reduce cardiovascular diseases.
Researchers at National Jewish Health have discovered a naturally occurring lipid, POPG, that reduces inflammation and inhibits infection by the influenza virus and RSV. The lipid offers a promising approach for the prevention and treatment of these respiratory infections.
Scientists found a unique lipid compound that amplifies sound and efficiently transmits it to the ear drums of insects, similar to toothed whales. The discovery opens up possibilities for new systems in ultrasound technologies.
The Biophysical Society has recognized five individuals with its 2013 awards for their significant contributions to biophysics and biomedical research. Carol Robinson and Joseph Zasadzinski received awards for their innovative work on mass spectrometry and lipid structures, respectively.