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Centenarian neuroscientist inspires blueprint for vibrant longevity through mentorship and connection

A study by Dr. Esther Sternberg highlights the importance of social engagement, intellectual stimulation, purposeful activity, humor, and spiritual exploration in achieving exceptional cognitive and social functioning in advanced age. Dr. Reichlin's example challenges conventional assumptions about aging trajectories.

SourceGenomic Press·JournalBrain Medicine·TypeNews article·DateSep 9, 2025

New study links exosomes to biological aging

Researchers found that exosomes from senescent cells and circulatory exosomes carry molecular signatures associated with biological aging and cellular senescence. These signatures include proteins, lipids, and microRNAs linked to inflammation, oxidative stress, and tissue remodeling.

SourceImpact Journals LLC·JournalAging-US·TypeNews article·DateSep 2, 2025

The best ways to prevent falls in aged care homes

A major international review found that targeted approaches such as regular supervised exercise, vitamin D supplements, and improved nutrition can significantly reduce falls in aged care homes. The study also highlights the importance of individualized programs delivered with strong staff engagement.

SourceFlinders University·JournalCochrane Database of Systematic Reviews·TypeMeta-analysis·DateAug 27, 2025

Exercise may slow epigenetic aging

A new study suggests that regular exercise can influence epigenetic aging and potentially reverse it, offering a promising way to extend healthspan. Physical fitness is closely associated with slower epigenetic aging, and sedentary behavior may have detrimental effects on the body's internal aging process.

SourceImpact Journals LLC·JournalAging-US·TypeNews article·DateAug 12, 2025

The first 25 years of SuperAger research

SuperAgers, individuals with exceptional memory performance beyond their age, have been studied for 25 years. Their brains show a distinct neurobiological profile, linked to resistance and resilience mechanisms that may prevent Alzheimer's disease progression.

SourceNorthwestern University·JournalAlzheimer s & Dementia·DateAug 7, 2025

Clearer conversations, better care: New guide highlights best practices for communicating with older adults

The report provides evidence-based strategies to improve communication between clinicians and patients 65 and older, addressing common barriers such as low health literacy and cognitive changes. It emphasizes adapting communication techniques to use simpler instructions and maintaining patient dignity and autonomy., A new guide from th...

Persistently, intensely grieving relations are nearly twice as likely to die within 10 years after losing a loved one

A large-scale study published in Frontiers in Public Health found that individuals experiencing persistent and intense grief are nearly twice as likely to die within 10 years after losing a loved one. The study followed a cohort of 1,735 bereaved individuals and found that those with high grief symptom levels had significantly higher r...

SourceFrontiers·JournalFrontiers in Public Health·TypeObservational study·DateJul 25, 2025

National Center to Reframe Aging partners with Pennsylvania Department of Aging to strengthen communications about senior centers

The National Center to Reframe Aging is partnering with the Pennsylvania Department of Aging to develop effective communication strategies for senior community centers. Effective reframing will increase public awareness, engagement, and investment in these vital spaces where older people can remain active, connected, and valued.

Lonely adults may have a higher risk of diabetes

A study presented at the Endocrine Society's annual meeting found that socially isolated older adults are 34% more likely to have diabetes and 75% more likely to have poor blood sugar control. Social isolation is being recognized as a critical social determinant of health, highlighting its importance in caring for older patients.

People with ‘young brains’ outlive ‘old-brained’ peers, Stanford Medicine scientists find

Researchers developed a blood-based indicator of organ age and found that individuals with young brains have a lower risk of developing diseases associated with their brain. The study also showed that organs' biological ages can predict health outcomes, such as increased risk of Alzheimer's disease for those with an old brain.

SourceStanford Medicine·JournalNature Medicine·TypeData/statistical analysis·DateJul 9, 2025

USC study: mindfulness meditation can sharpen attention in adults of all ages

A new study from the University of Southern California reveals that just 30 days of guided mindfulness meditation can significantly enhance key aspects of attentional control. The study demonstrates that even short-term meditation can lead to measurable cognitive improvements, particularly in reaction speed.

SourceUniversity of Southern California·JournaleNeuro·TypeRandomized controlled/clinical trial·DateJul 8, 2025

NUS Medicine researchers develop a better and more accurate biological ageing clock

Researchers developed an improved biological ageing clock, LinAge2, that offers doctors a practical way to assess how quickly a person is ageing and what can be done to slow it down. The new algorithm-powered tool outperforms other clinical models in predicting long-term mortality and health outcomes.

SourceNational University of Singapore, Yong Loo Lin School of Medicine·Journalnpj Aging·TypeComputational simulation/modeling·DateJun 8, 2025

Live longer

A combination of Rapamycin and Trametinib therapies significantly prolongs the life of mice by up to 30%, reducing chronic inflammation and delaying cancer onset. The unique combination achieves novel effects on gene expression, offering a potential geroprotector approach to extend human lifespan.

SourceMax Planck Institute for Biology of Ageing·JournalNature Aging·TypeExperimental study·DateMay 28, 2025

Older adults are getting infected with HIV, but prevention focuses on young people

A study published in The Lancet Healthy Longevity reveals that older adults in sub-Saharan Africa are at risk of HIV infection, particularly those who have experienced social stigma and lack access to education. Interventions such as repeated testing, PrEP, and awareness campaigns can help reduce infections among the elderly.

SourceUniversity of the Witwatersrand·JournalThe Lancet Healthy Longevity·DateMay 15, 2025

Mount Sinai researchers in semifinals of $101 million XPRIZE Healthspan, a competition seeking innovative approaches to aging well

The Mount Sinai team's NYC-Vita trial combines lifestyle and pharmaceutical interventions to rebalance the immune system and restore health in older adults. The ambitious effort aims to develop practical, science-driven interventions that extend life and restore energy, focus, and strength.

Biological age predicts cardiovascular disease morbidity and mortality

A multicentre study found that biological ageing, measured by frailty index and telomere length, can predict cardiovascular disease risk more accurately than traditional tools. The study, involving over 14,000 individuals, suggests that incorporating biological age into risk assessments could improve cardiovascular health outcomes.