Dentistry
Articles tagged with Dentistry
Don't rush into braces with disc displacement: experts reveal the science of sequential therapy
Mothers’ prenatal immunity shapes lifelong resistance to gum disease - new study
A new study reveals how maternal antibodies program the mouth to resist aggressive bacteria and prevent bone loss associated with adult gum disease. Maternal IgG also regulates the timing of barrier sealing in the oral epithelium.
Opioids for dental pain still more common in US
A new study shows that while dental opioid prescription fills in the US have dropped by 27% since 2021, the rate remains higher than in other developed countries and the US territory of Puerto Rico. The study suggests that some US dentists are still overprescribing opioids.
Kids most in need of dental care least likely to benefit from school programs
A study found that children who need dental care the most are less likely to participate in school-based cavity prevention programs, which can lead to significant savings for state Medicaid programs. Improving participation among high-risk children could save up to $2.4 million annually.
Exploring the teamwork of two genes in shaping dental and facial features
A team of researchers found that Gli2 and Gli3 function synergistically to regulate tooth root morphogenesis. Their study revealed a critical interaction between HH signaling and TGF-β signaling, which is essential for normal root development.
People who can’t afford dental care may be at higher risk of developing cardiovascular disease, dementia
A new study found that older people who forego necessary dental procedures due to financial barriers may experience heart failure, a heart attack, a stroke, or dementia. The researchers suggest that alleviating upstream factors such as financial constraints could prevent chronic disease.
University of Cincinnati researchers discover clear link between chronic kidney disease and periodontal disease
Researchers found a clear connection between oral health and kidney health, with immune dysregulation and systemic inflammation driving the relationship. The study highlights the need for physicians to integrate oral and renal health into clinical care systems.
A stiff defense: Rethinking gum disease
New research demonstrates that restoring the physical stiffness of the gingival tissue can fundamentally change how cells respond to infection, potentially paving the way for new treatments. The study uses a hydrogel system to investigate how gum tissue stiffness impacts periodontal disease inflammation.
Effects of chronic occupational dental light exposure on retinal health
A study found that dentists have a higher prevalence of vision-related problems due to prolonged exposure to artificial lighting. Chronic dental lighting caused retinal damage, disruption of the blood-retinal barrier, and inflammation, ultimately impairing visual health.
UT Health San Antonio announces $6.5 million gift to strengthen pediatric health workforce through new Harvey E. Najim Pediatric Health Scholars Program
The program aims to support future pediatric-focused professionals in dentistry, medicine and nursing through competitive scholarships and training. With the gift, UT Health San Antonio will expand access to high-quality care for children and families in Bexar County.
Snus linked to gum damage – gaps in knowledge about white snus
A systematic review found consistent evidence that snus causes gum recession, particularly with loose snus. White snus has virtually no studies on its long-term oral health effects, creating a significant knowledge gap.
Decoding the pattern and mechanisms that provide hardness to tooth enamel
A study on mouse incisors reveals a cellular mechanism behind the unique decussation patterns of tooth enamel, which form the enamel's hardness through directional sliding and coordinated migration of ameloblasts. The findings provide new insights into how dental stem and progenitor cells maintain and repair enamel-forming tissues.
New molecular switch that boosts tooth regeneration discovered
Researchers discover SMAD7 acts as a positive regulator of Wnt/β-catenin signaling, promoting dental pulp stem cell regeneration and tissue repair. The study provides new insights into the molecular mechanisms governing tooth regeneration and holds promise for regenerative endodontic procedures.
Gnaw-y by nature: Researchers discover neural circuit that rewards gnawing behavior in rodents
A new neural circuit has been identified that rewards gnawing behavior in rodents, driving a release of dopamine in the brain. This discovery could help explain oral health issues in humans, including bruxism and malocclusion.
Altered copper metabolism is a crucial factor in inflammatory bone diseases
Copper metabolism plays a crucial role in inflammatory bone diseases, with copper overload suppressing glycogen synthesis and increasing inflammatory activity. Researchers found that cuproptosis, a form of programmed cell death, can lead to bone weakening and osteoclast formation, providing a potential new therapeutic target.
How periodontitis-linked bacteria accelerate osteoporosis-like bone loss through the gut
Research reveals that salivary bacteria from gum disease alter gut metabolism, driving osteoclast activity and systemic bone loss. Microbial metabolites like indole-3-lactic acid inhibit osteoclast differentiation and activity.
One in three diagnosed with pre-diabetes or diabetes during dental appointment
A new study by King's College London found that over 35% of patients without reported diabetes had high blood sugar levels consistent with pre-diabetes. The research uses a simple finger-prick blood test to screen for the condition, which can be done during dental appointments in as little as six minutes.
Children with poor oral health more often develop cardiovascular disease as adults
A study from the University of Copenhagen found that children with multiple tooth cavities or severe gingivitis have a significantly higher incidence of stroke, heart attack, and coronary artery disease as adults. Lifestyle factors may play an important role in this correlation.
Call for dentists to reduce unnecessary nitrous oxide use
A study by UCL researchers found large variations in nitrous oxide use across UK dental services, with some sites emitting up to 1,849 kg CO₂e per week. The team recommends reducing wastage, standardizing practice, and considering alternatives to minimize environmental impact.
What Zinc concentration in teeth reveals
Researchers have quantified zinc concentration in teeth using 3D X-ray tomography systems. They found a sharp increase in zinc concentration from the outside to the inside of the tooth, particularly near the pulp. This study has implications for dental care and material selection.
Toothbrush-activated powder whitens, repairs and protects teeth
Researchers have designed a prototype powder that activates to whiten and repair teeth, promoting oral health. The system uses the piezoelectric effect to generate ROS, killing bacteria and reducing inflammation in lab demonstrations.
Exploring the complex relationship between oral health and dementia
Research highlights overlooked social mechanisms connecting oral health, eating and speaking difficulties, and cognitive decline. A six-year longitudinal study found poor oral health is a strong predictor of weight loss in older adults.
Mechanisms by which smoking worsens periodontitis discovered
Researchers identified altered gene expression in smokers with periodontitis, leading to weakened gum epithelial integrity and excessive inflammation. A new target molecule, CXCL12, was found to drive immune-cell recruitment and inflammation, making it a potential therapeutic approach.
A new ally against tooth decay: Arginine offers sweet relief
A clinical trial shows that arginine can modify plaque formation on teeth, thereby protecting against dental caries. The study found that arginine reduced the acidity of biofilms and altered their carbohydrate structure, making them less harmful.
Chew on this: Losing teeth weakens key memory hub in mouse brains
Aging mice without teeth experience cognitive decline due to inflammation and cell loss in the hippocampus, essential for memory formation. The study suggests that maintaining chewing ability may be a strategy to preserve cognitive function later in life.
New composite hydrogel shows promise for treating dental pulp infection
A new composite hydrogel containing Li-Ca-Si bioceramics particles and gelatin methacryloyl matrix has shown promise in treating dental pulp infections by facilitating innervation and odontogenic differentiation. The hydrogel promoted Schwann cell regeneration, cytocompatibility for dental pulp stem cells, and proliferation of DPSCs.
Robert I. Schattner Oral Health Center for People with Disabilities established at Hebrew University-Hadassah School of Dental Medicine
The Hebrew University-Hadassah School of Dental Medicine has established a new center dedicated to providing quality dental care for people with physical, cognitive, and complex medical conditions. The center will offer holistic, multidisciplinary care under one roof, serving approximately 30-40 patients daily.
Comparative transcriptomic analysis of human maxillary and mandibular tooth germs reveals discrepancies in gene expression patterns
The study found that upper and lower tooth germs exhibit distinct transcriptomic profiles at the cap stage, with maxillary-enriched genes associated with morphogenesis and lower-enriched genes linked to mineralization. The researchers also validated key findings using RT-qPCR and immunofluorescence staining.
Sweet tooth: How blood sugar migration in diabetes affects cavity development
Researchers from The University of Osaka found that blood sugar migration to saliva in individuals with type 2 diabetes causes an imbalance in the oral microbiome, leading to cavity development. Improved glycemic control reduces this imbalance and the risk of tooth decay.
Cutting-edge 3D AI technology transforming dental care for children
A new study reveals that a hand-held, wireless intraoral scanner paired with AI-assisted software can identify early childhood tooth decay as accurately as visual exams. The technology creates a detailed 3D model of a child's mouth within minutes, providing a comprehensive picture of their dental health.
Brushing well is more important for a healthy mouth than high-tech tools
A recent study by Tim Thomassen concludes that good daily habits, including proper brushing techniques and adequate brushing time, are more crucial for preventing oral diseases than expensive dental gadgets.
Do oral bacteria from tooth infections worsen diabetes risk?
Researchers found that oral bacteria from tooth infections can worsen diabetes risk through IL-17-driven inflammation. The study revealed a mechanistic link between Porphyromonas gingivalis-induced periapical disease and systemic metabolic dysfunction.
Making quieter dental drills to reduce dental anxiety
Researchers have designed a quieter dental drill to address the anxiety-causing sound of traditional drills, which can reach nearly 20 kilohertz. The new design optimizes blade geometry and exhaust port to minimize noise while maintaining performance, with the goal of reducing discomfort in patients.
Antimicrobial peptides in oral medicine: From mechanisms to clinical translation
Researchers have identified antimicrobial peptides as a safe alternative to traditional antibiotics for treating oral diseases. These peptides can inhibit bacterial growth, regulate inflammation, and promote tissue repair, making them a game-changer in oral medicine.
Teeth of babies of stressed mothers come out earlier, suggests study
Research shows that infants of stressed mothers have an earlier and faster tooth eruption, with more teeth by six months of age. Cortisol levels during late pregnancy are associated with this accelerated process.
Root canal treatment reduces heart disease and diabetes risk
A study published in Journal of Translational Medicine found that successful root canal treatment can reduce inflammation linked to heart disease and improve levels of blood sugar and cholesterol. The researchers discovered a link between monitoring blood metabolic markers after dental treatment, which could help assess recovery and risk.
New resources help dentists identify patients at risk for cardiovascular disease
Dental teams can identify hypertension and cardiovascular disease risk through blood pressure screenings in routine care visits. The American Heart Association's Healthy Smiles, Healthy Hearts initiative provides standard blood pressure screening and referral guides, empowering dentists to connect patients with primary care.
Children’s dental health still very poor despite interventions
Despite government initiatives, UK children's dental health remains poor, with 26.9% of five-year-olds experiencing tooth decay and disadvantaged areas facing higher rates of tooth extractions. The Child of the North initiative highlights the need for scaled-up and strengthened schemes to address this issue.
New gel restores dental enamel and could revolutionise tooth repair
Researchers have developed a bioinspired material that can regenerate demineralized or eroded enamel, strengthen healthy enamel, and prevent future decay. The new gel, applied like standard fluoride treatments, promotes controlled growth of new mineral to recover enamel structure and properties.
Tooth code cracked: Scientists find cells that know when, where, and how to grow teeth
Researchers discovered that young dental cells are directed by their position along the lingual-buccal axis to grow into distinct structures. Cells on one side formed tooth enamel, while those on the other side focused on stem cell activity and supporting tissue growth.
Gum disease and cavities linked to increased stroke risk
A study published in Neurology Open Access found that people with both gum disease and cavities have a higher risk of ischemic stroke. Researchers analyzed data from 5,986 adults and found that those with both conditions had an 86% higher risk of stroke compared to those with healthy mouths.
Gum disease associated with changes in the brain
A recent study has found an association between gum disease and changes in the brain's white matter, which can affect memory, thinking, balance, and coordination. Adults with gum disease had more white matter hyperintensities, a type of damage that can increase stroke risk.
Less pain, same results? Researchers explore drill-free treatments for cavities in older adults
A new study led by Suchitra Nelson aims to advance previous research on two less-invasive options for treating and preventing cavities. The study focuses on older adults living in subsidized housing with limited access to dental care, using Silver Diamine Fluoride (SDF) and Atraumatic Restorative Treatment (ART).
Korea University researchers advance orthodontics with AI-assisted growth prediction
Researchers from Korea University Anam Hospital and KAIST introduce an AI system that accurately predicts a child's pubertal growth peak from a single radiograph, streamlining orthodontic treatment. The Attend-and-Refine Network (ARNet-v2) improves efficiency and accuracy, reducing radiation exposure and costs for young patients.
Crown jewel of dental restoration technology may be in sight
The UT Dallas researchers have developed a technology that enables same-day, 3D-printed dental restorations made of zirconia, the gold-standard material for permanent dental work. This breakthrough could make same-day permanent dental restorations possible with a reduced debinding time from hours to less than 30 minutes.
Afraid of the dentist? The cause may be something different from what you think
Research shows that painful childhood experiences like bullying and violence can cause dental fear in young people, leading to anxiety and avoidance of dental treatment. The study found a stronger association between painful childhood experiences and dental fear in girls than boys.
Unveiling the therapeutic potential of abaloparatide in treating periodontal dehiscence
Researchers demonstrate that intraoral administration of abaloparatide combined with orthodontic force supports alveolar bone thickening. ABL-induced alveolar bone formation is linked to the focal adhesion pathway, where FAK activation plays a crucial role.
One in three young adults skip the dentist, and that’s a problem
A new study from Tufts University found nearly one in three young adults skipped dental visits due to cost and lack of insurance coverage. Young adults were more likely to skip medical care, struggle with copays, and report poor mental health or memory problems.
For young adults, the color of their teeth is important
A study by the University of Gothenburg found that young individuals place a higher importance on even tooth color, with an average score of 8. White teeth scored 7.25, highlighting the significance of aesthetics in oral health.
Pensoft to co-publish Problems of Dental Medicine with Faculty of Dental Medicine at Medical University Sofia
Problems of Dental Medicine joins Pensoft's ARPHA platform, streamlining publishing workflows and increasing accessibility for dental research. The journal will benefit from improved infrastructure, increased visibility, and new opportunities for advancing dental science.
Cracks beneath the surface: new consensus sheds light on cemental tear
Researchers developed standardized guidelines to diagnose and treat cemental tears, reducing misdiagnosis and improving patient outcomes. The consensus identifies key risk factors, diagnostic strategies, and treatment principles, empowering clinicians to recognize and manage this hidden threat more effectively.
Oral health treatment in patients due for surgery is associated with significantly lower rates of postoperative pneumonia and shorter hospital stays, per observational study in one Japanese hospital, suggesting it might reduce infection risk
A single-center observational study found that planned preoperative oral care at least 2 weeks prior to surgery significantly reduced rates of postoperative pneumonia and shortened hospital stays. The results suggest that oral health treatment could be an effective strategy for reducing infection risk in surgical patients.
Teens who lose teeth to decay and injury nearly twice as likely to be bullied, study reveals
A study of over 4,400 Australian children found that those experiencing tooth loss were more than four times as likely to be bullied. Children from lower socioeconomic backgrounds and rural areas were disproportionately affected. The researchers highlight the need for improved access to dental care and prevention programs.
Dental fear is widespread—But most people want treatment
A new study found that nearly three out of four adults suffer from dental fear, with 45.8% experiencing moderate fear and 26.8% severe fear. Most individuals interested in overcoming their fear are open to free, brief treatment options, such as virtual dental fear treatments using apps and telehealth.
Hypoxia leads to reduced dental bone formation during orthodontic tooth movement in rats
Research reveals that hypoxia reduces alveolar bone levels and osteoblast differentiation after orthodontic tooth movement, while increasing osteoclastic activity. This study provides critical insights into the bone remodeling process under hypoxia.
Toothpaste made from hair provides natural root to repair teeth
Researchers at King's College London discovered that keratin can repair tooth enamel and stop early stages of decay. Keratin forms a protective coating that mimics the structure and function of natural enamel.
Osteogenesis – Angiogenesis coupling via interlineage paracrine signaling
Researchers have discovered a specialized mesenchymal-endothelial crosstalk that supports angiogenesis and osteogenesis, enabling periodontal bone regeneration. This communication network between mesenchymal stem cells and endothelial cells drives tissue repair and regeneration, holding promise for dental therapeutic strategies and bro...
National study finds healthcare provider stigma toward substance use disorder varies sharply by condition and provider
A national study found that healthcare providers exhibit varying levels of stigma towards patients with substance use disorders (SUD), particularly for opioid and stimulant use. This stigma leads to missed opportunities for care and is often embedded in clinical encounters.
New study identifies key ingredients to expanding dental care in the safety net
A new study from the University at Albany's Oral Health Workforce Research Center analyzed data on Federally Qualified Health Centers and found that capacity-building steps such as investing in skilled providers and improving infrastructure enable more people to access essential health services. The study identified three leading facto...