Articles tagged with Dentistry
A study on mouse incisors reveals a cellular mechanism behind the unique decussation patterns of tooth enamel, which form the enamel's hardness through directional sliding and coordinated migration of ameloblasts. The findings provide new insights into how dental stem and progenitor cells maintain and repair enamel-forming tissues.
A new neural circuit has been identified that rewards gnawing behavior in rodents, driving a release of dopamine in the brain. This discovery could help explain oral health issues in humans, including bruxism and malocclusion.
Researchers discover SMAD7 acts as a positive regulator of Wnt/β-catenin signaling, promoting dental pulp stem cell regeneration and tissue repair. The study provides new insights into the molecular mechanisms governing tooth regeneration and holds promise for regenerative endodontic procedures.
Copper metabolism plays a crucial role in inflammatory bone diseases, with copper overload suppressing glycogen synthesis and increasing inflammatory activity. Researchers found that cuproptosis, a form of programmed cell death, can lead to bone weakening and osteoclast formation, providing a potential new therapeutic target.
Research reveals that salivary bacteria from gum disease alter gut metabolism, driving osteoclast activity and systemic bone loss. Microbial metabolites like indole-3-lactic acid inhibit osteoclast differentiation and activity.
A new study by King's College London found that over 35% of patients without reported diabetes had high blood sugar levels consistent with pre-diabetes. The research uses a simple finger-prick blood test to screen for the condition, which can be done during dental appointments in as little as six minutes.
A study from the University of Copenhagen found that children with multiple tooth cavities or severe gingivitis have a significantly higher incidence of stroke, heart attack, and coronary artery disease as adults. Lifestyle factors may play an important role in this correlation.
A study by UCL researchers found large variations in nitrous oxide use across UK dental services, with some sites emitting up to 1,849 kg CO₂e per week. The team recommends reducing wastage, standardizing practice, and considering alternatives to minimize environmental impact.
Researchers have quantified zinc concentration in teeth using 3D X-ray tomography systems. They found a sharp increase in zinc concentration from the outside to the inside of the tooth, particularly near the pulp. This study has implications for dental care and material selection.
Researchers have designed a prototype powder that activates to whiten and repair teeth, promoting oral health. The system uses the piezoelectric effect to generate ROS, killing bacteria and reducing inflammation in lab demonstrations.
Research highlights overlooked social mechanisms connecting oral health, eating and speaking difficulties, and cognitive decline. A six-year longitudinal study found poor oral health is a strong predictor of weight loss in older adults.
Researchers identified altered gene expression in smokers with periodontitis, leading to weakened gum epithelial integrity and excessive inflammation. A new target molecule, CXCL12, was found to drive immune-cell recruitment and inflammation, making it a potential therapeutic approach.
A clinical trial shows that arginine can modify plaque formation on teeth, thereby protecting against dental caries. The study found that arginine reduced the acidity of biofilms and altered their carbohydrate structure, making them less harmful.
Aging mice without teeth experience cognitive decline due to inflammation and cell loss in the hippocampus, essential for memory formation. The study suggests that maintaining chewing ability may be a strategy to preserve cognitive function later in life.
A new composite hydrogel containing Li-Ca-Si bioceramics particles and gelatin methacryloyl matrix has shown promise in treating dental pulp infections by facilitating innervation and odontogenic differentiation. The hydrogel promoted Schwann cell regeneration, cytocompatibility for dental pulp stem cells, and proliferation of DPSCs.
The Hebrew University-Hadassah School of Dental Medicine has established a new center dedicated to providing quality dental care for people with physical, cognitive, and complex medical conditions. The center will offer holistic, multidisciplinary care under one roof, serving approximately 30-40 patients daily.
The study found that upper and lower tooth germs exhibit distinct transcriptomic profiles at the cap stage, with maxillary-enriched genes associated with morphogenesis and lower-enriched genes linked to mineralization. The researchers also validated key findings using RT-qPCR and immunofluorescence staining.
Researchers from The University of Osaka found that blood sugar migration to saliva in individuals with type 2 diabetes causes an imbalance in the oral microbiome, leading to cavity development. Improved glycemic control reduces this imbalance and the risk of tooth decay.
A new study reveals that a hand-held, wireless intraoral scanner paired with AI-assisted software can identify early childhood tooth decay as accurately as visual exams. The technology creates a detailed 3D model of a child's mouth within minutes, providing a comprehensive picture of their dental health.
A recent study by Tim Thomassen concludes that good daily habits, including proper brushing techniques and adequate brushing time, are more crucial for preventing oral diseases than expensive dental gadgets.
Researchers found that oral bacteria from tooth infections can worsen diabetes risk through IL-17-driven inflammation. The study revealed a mechanistic link between Porphyromonas gingivalis-induced periapical disease and systemic metabolic dysfunction.
Researchers have designed a quieter dental drill to address the anxiety-causing sound of traditional drills, which can reach nearly 20 kilohertz. The new design optimizes blade geometry and exhaust port to minimize noise while maintaining performance, with the goal of reducing discomfort in patients.
Researchers have identified antimicrobial peptides as a safe alternative to traditional antibiotics for treating oral diseases. These peptides can inhibit bacterial growth, regulate inflammation, and promote tissue repair, making them a game-changer in oral medicine.
Research shows that infants of stressed mothers have an earlier and faster tooth eruption, with more teeth by six months of age. Cortisol levels during late pregnancy are associated with this accelerated process.
A study published in Journal of Translational Medicine found that successful root canal treatment can reduce inflammation linked to heart disease and improve levels of blood sugar and cholesterol. The researchers discovered a link between monitoring blood metabolic markers after dental treatment, which could help assess recovery and risk.
Dental teams can identify hypertension and cardiovascular disease risk through blood pressure screenings in routine care visits. The American Heart Association's Healthy Smiles, Healthy Hearts initiative provides standard blood pressure screening and referral guides, empowering dentists to connect patients with primary care.
Despite government initiatives, UK children's dental health remains poor, with 26.9% of five-year-olds experiencing tooth decay and disadvantaged areas facing higher rates of tooth extractions. The Child of the North initiative highlights the need for scaled-up and strengthened schemes to address this issue.
Researchers have developed a bioinspired material that can regenerate demineralized or eroded enamel, strengthen healthy enamel, and prevent future decay. The new gel, applied like standard fluoride treatments, promotes controlled growth of new mineral to recover enamel structure and properties.
Researchers discovered that young dental cells are directed by their position along the lingual-buccal axis to grow into distinct structures. Cells on one side formed tooth enamel, while those on the other side focused on stem cell activity and supporting tissue growth.
A study published in Neurology Open Access found that people with both gum disease and cavities have a higher risk of ischemic stroke. Researchers analyzed data from 5,986 adults and found that those with both conditions had an 86% higher risk of stroke compared to those with healthy mouths.
A recent study has found an association between gum disease and changes in the brain's white matter, which can affect memory, thinking, balance, and coordination. Adults with gum disease had more white matter hyperintensities, a type of damage that can increase stroke risk.
A new study led by Suchitra Nelson aims to advance previous research on two less-invasive options for treating and preventing cavities. The study focuses on older adults living in subsidized housing with limited access to dental care, using Silver Diamine Fluoride (SDF) and Atraumatic Restorative Treatment (ART).
Researchers from Korea University Anam Hospital and KAIST introduce an AI system that accurately predicts a child's pubertal growth peak from a single radiograph, streamlining orthodontic treatment. The Attend-and-Refine Network (ARNet-v2) improves efficiency and accuracy, reducing radiation exposure and costs for young patients.
The UT Dallas researchers have developed a technology that enables same-day, 3D-printed dental restorations made of zirconia, the gold-standard material for permanent dental work. This breakthrough could make same-day permanent dental restorations possible with a reduced debinding time from hours to less than 30 minutes.
Research shows that painful childhood experiences like bullying and violence can cause dental fear in young people, leading to anxiety and avoidance of dental treatment. The study found a stronger association between painful childhood experiences and dental fear in girls than boys.
Researchers demonstrate that intraoral administration of abaloparatide combined with orthodontic force supports alveolar bone thickening. ABL-induced alveolar bone formation is linked to the focal adhesion pathway, where FAK activation plays a crucial role.
A new study from Tufts University found nearly one in three young adults skipped dental visits due to cost and lack of insurance coverage. Young adults were more likely to skip medical care, struggle with copays, and report poor mental health or memory problems.
A study by the University of Gothenburg found that young individuals place a higher importance on even tooth color, with an average score of 8. White teeth scored 7.25, highlighting the significance of aesthetics in oral health.
Problems of Dental Medicine joins Pensoft's ARPHA platform, streamlining publishing workflows and increasing accessibility for dental research. The journal will benefit from improved infrastructure, increased visibility, and new opportunities for advancing dental science.
Researchers developed standardized guidelines to diagnose and treat cemental tears, reducing misdiagnosis and improving patient outcomes. The consensus identifies key risk factors, diagnostic strategies, and treatment principles, empowering clinicians to recognize and manage this hidden threat more effectively.
A single-center observational study found that planned preoperative oral care at least 2 weeks prior to surgery significantly reduced rates of postoperative pneumonia and shortened hospital stays. The results suggest that oral health treatment could be an effective strategy for reducing infection risk in surgical patients.
A study of over 4,400 Australian children found that those experiencing tooth loss were more than four times as likely to be bullied. Children from lower socioeconomic backgrounds and rural areas were disproportionately affected. The researchers highlight the need for improved access to dental care and prevention programs.
A new study found that nearly three out of four adults suffer from dental fear, with 45.8% experiencing moderate fear and 26.8% severe fear. Most individuals interested in overcoming their fear are open to free, brief treatment options, such as virtual dental fear treatments using apps and telehealth.
Research reveals that hypoxia reduces alveolar bone levels and osteoblast differentiation after orthodontic tooth movement, while increasing osteoclastic activity. This study provides critical insights into the bone remodeling process under hypoxia.
Researchers at King's College London discovered that keratin can repair tooth enamel and stop early stages of decay. Keratin forms a protective coating that mimics the structure and function of natural enamel.
Researchers have discovered a specialized mesenchymal-endothelial crosstalk that supports angiogenesis and osteogenesis, enabling periodontal bone regeneration. This communication network between mesenchymal stem cells and endothelial cells drives tissue repair and regeneration, holding promise for dental therapeutic strategies and bro...
A national study found that healthcare providers exhibit varying levels of stigma towards patients with substance use disorders (SUD), particularly for opioid and stimulant use. This stigma leads to missed opportunities for care and is often embedded in clinical encounters.
A new study from the University at Albany's Oral Health Workforce Research Center analyzed data on Federally Qualified Health Centers and found that capacity-building steps such as investing in skilled providers and improving infrastructure enable more people to access essential health services. The study identified three leading facto...
A supplemental issue of JDR Clinical & Translational Research highlights the importance of investing in long-term faculty career development supported by HRSA programs. The publication showcases innovative work done by junior dental faculty, demonstrating the need to address pressing dental shortages and expand access to care.
A new dental implant wrapped in a biodegradable coating with stem cells and protein helps retain nerve tissue, enabling the implant to mimic real teeth's sensory feedback. The coating also expands to snugly fit the socket, preserving existing nerve endings.
A NYU College of Dentistry study found that topical treatments for kids' cavities can significantly prevent decay from worsening. The use of atraumatic restorations (ART) and silver diamine fluoride (SDF) in schools kept 62% and 55% of decayed surfaces under control, respectively.
Researchers have developed a miniaturized toothbrush-shaped ultrasound transducer that can provide accurate images of teeth and gums, offering a less invasive alternative to traditional periodontal probing. The device has been shown to produce high-quality images similar to those obtained with manual metal probes.
A multinational study involving Aarhus University sheds light on patients' attitudes toward AI in dental diagnostics. Patients view AI as a useful diagnostic tool but express concerns over data privacy and cost implications. The overwhelming majority insists on professional human oversight, echoing the views of dental professionals.
The AADOCR SCADA/Dentsply Sirona Research Award aims to support early-stage dentist-scientists by providing up to $10,000 for research projects and infrastructure establishment. The award's recipients must submit a report within 12 months of receiving the funding.
Researchers at IU and Regenstrief Institute developed an app that connects dentists to health information exchanges, providing timely access to patient medical history. This facilitates direct communication between dental clinicians and patients, enhancing care coordination and patient outcomes.
A study found that microRNA-27a promotes dental tissue regeneration by suppressing inflammation and activating Wnt/BMP signaling pathways. The researchers used human dental pulp stem cells to overexpress miRNA-27a, which led to the formation of new bone-like tissue in mice.
A global survey of 156 institutions found that technical limitations, such as haptic precision issues, and financial constraints are significant barriers to the adoption of VR-haptic technology in dental education. The study suggests that cost-reduction innovations and targeted faculty training are needed to address these challenges.
Using VR-haptic simulators can enhance skill acquisition and confidence among dental students during preclinical endodontic training. The study found that simulator practice reduced anxiety levels and improved performance metrics.
A cross-disciplinary research team from HKU has found a connection between oral microbiota and ASD, identifying 11 bacterial species as potential biomarkers. The study developed a prediction model with an 81% accuracy rate for early detection, paving the way for non-invasive screening tools during dental check-ups.
A deep learning model has been developed to identify tooth and sinus structures in dental X-rays with an accuracy of 98.2%, outperforming traditional detection methods. The system minimizes patient exposure to radiation and provides a cost-effective screening tool for early diagnosis and prompt intervention.