Stimulating two parts of the brain at the same time may create richer artificial touch sensations, according to a study published in Brain Stimulation. The study found that simultaneous stimulation of the primary somatosensory cortex and insular cortex produced qualitatively richer, multicomponent percepts in three patients.
A new clinical trial aims to test personalized brain stimulation targeting two pain-related brain networks for patients with severe, treatment-resistant central neuropathic pain. Researchers will use functional MRI to map each participant's brain and adjust stimulation settings based on individual responses.
A trial testing out-of-body experiences found no correlation with target identification, but participants unexpectedly described researchers' locations and activities. The unexpected findings may lead to the development of better evaluation methods and potentially support the case for out-of-body remote viewing.
A new University of Pittsburgh study found that low-frequency deep brain stimulation improves control of facial and tongue muscles involved in speaking and swallowing after traumatic brain injury. The treatment showed small but significant improvements in word intelligibility for one participant with TBI.
Researchers from Hebei Medical University review current evidence on prolonged disorders of consciousness (pDOC) management. They propose a brain communication network model to explain how brain injury leads to long-term unconsciousness, identifying key brain electrical signaling activity measures for diagnosis and treatment.
Researchers analyzed EBRAINS-hosted brain data to determine that whole-brain activity patterns predict stimulation outcomes better than local recordings. Targeting specific sensorimotor and visual networks reduces response variability by up to 24%. This study highlights the value of open datasets for enabling large-scale analyses.
Researchers developed a hybrid technology combining human learning and machine learning in noninvasive BCIs, producing rapid and sustained gains in motor imagery control. The study demonstrates significant scientific and technological advancement in BCIs, establishing a scalable pathway toward robust neural interfaces.
The new section in JMIR Neurotechnology focuses on the responsible and ethical use of neurotechnology. Submissions welcome for original research, case series, theoretical viewpoints, and data-driven analyses on ethics and policy in neurotechnology.
A team from UNIGE has improved a non-invasive brain stimulation technique called temporal interference stimulation, allowing deeper and more targeted stimulation. The breakthrough enables the potential application of this method in treating neurological and psychiatric disorders such as Parkinson's disease and depression without surgery.
Researchers at MUSC Hollings Cancer Center found that stimulating a specific brain region regulates self-control reduced how much people smoked, with participants showing significant reductions in smoking and cravings after treatment
A study published in Pediatric Research demonstrated the safety of intranasal breast milk therapy in brain-injured newborns. The therapy was found to be effective in supporting nervous system regeneration without causing any adverse effects.
Researchers at USC, Caltech, and UC Irvine have developed a two-way brain interface that allows patients to control wearable robotic legs using their thoughts. The system accurately detected brain signals indicating the intent to walk about 92% of the time and restored walking sensations with about 93% accuracy in an early proof-of-con...
Scientists employed targeted sound vibrations to influence brain behavior in a computer game, revealing robust effects on neurotransmitter levels and choice behavior. The technique may offer new treatments for conditions like depression and addiction, which involve disrupted brain regions.
Researchers from UC San Francisco successfully decoded brain activity patterns associated with walking, enabling the development of personalized neural biomarkers for movement state classification. This breakthrough could lead to more effective adaptive DBS systems that adjust stimulation in response to a patient's activity state.
Researchers used transcranial alternating current stimulation to synchronize frontal and parietal lobes, increasing participants' ability to make altruistic choices. This study provides new insights into the neural basis of social decisions and has implications for future research on cooperation.
Researchers have developed a long, needle-thin brain electrode with channels that enables neural signal recording and precisely targeted medication delivery across different brain regions. The technology has primarily been developed for basic research but may be important for future treatments in epilepsy and other neurological diseases.
A new study identifies the somato-cognitive action network (SCAN) as responsible for Parkinson's disease symptoms, which can be treated with non-invasive transcranial magnetic stimulation. Targeting this network improves symptoms more than twice as much as treatments targeting nearby brain areas.
A blind patient partially recovered natural vision through electrical stimulation of the visual cortex, independent of the implant. The recovery was sustained over time and remained even after the device was removed, suggesting individual factors may have contributed to this outcome.
A large multicentre clinical trial of a brain stimulation device (TNS) for ADHD showed no significant change in symptoms. The study was conducted by King's College London and tested 150 children and adolescents, finding the device to be safe but ineffective.
Researchers at the University of Illinois discovered that propofol, a common anesthetic agent, can improve cognitive function after surgery in older individuals. Additionally, intranasal insulin was found to mitigate age-related memory impairment by modulating neuroinflammatory mechanisms.
Trigeminal neuralgia is a debilitating condition causing sudden, severe electric shock-like pain in the face. University Hospitals has successfully treated two initial patients with the OneRF Trigeminal Nerve Ablation System, providing complete pain relief without complications. The minimally-invasive procedure uses radiofrequency ener...
A new study published in Frontiers in Human Neuroscience reveals that a visual training program called Perceptual Attention Therapy (PATH) produces rapid improvements in reading, attention, memory, and executive function after concussion. PATH addresses underlying visual timing deficits before strengthening specific cognitive skills.
The EBRAINS Summit 2025 will bring together experts to assess how neuroscience can drive medical progress, digital innovation, and responsible data use. Preliminary results from the EPINOV clinical trial, integrating virtual brain technology for epilepsy surgery planning, will be presented.
Researchers developed a new tool, Fear Avoidance after Concussion Tool (FACT), to assess fear avoidance behavior following a concussion. The 28-item questionnaire can be completed in five minutes, enabling targeted management for individuals at risk of persisting post-concussion symptoms.
Researchers used brain stimulation to synchronize communication between visual regions and enhance motion perception in stroke patients. The approach showed significant improvements in visual fields and real-world performance, suggesting a faster, more accessible therapy for hemianopia recovery.
A team of researchers from Rice University and the Houston Methodist Research Institute will study how the brain responds to neural implants. They aim to develop more stable and longer-lasting brain-computer interfaces and neuroprosthetics, which could treat neurological disorders such as Parkinson’s disease, epilepsy, and stroke.
Spanish researchers at UMH have developed a new generation of visual neuroprosthesis capable of bidirectional communication with the cerebral cortex. The system uses a small external camera to capture images, which are processed electronically and converted into electrical stimulation patterns sent to the occipital cortex. Participants...
A University of Minnesota Medical School research team, led by Ziad Nahas, has been awarded a $4.4 million grant to explore how large-scale brain networks regulate mood in bipolar disorder. The team will test a novel type of brain stimulation called Personalized and Adaptive Cortico Electrostimulation (PACE) to relieve symptoms and ide...
A comprehensive review of emerging neuromodulation techniques reveals their potential to treat treatment-resistant OCD. Targeting abnormal brain activity, these methods aim to normalize circuits underlying decision-making and emotion regulation.
The Mount Sinai team will investigate neural mechanisms underlying bipolar disorder and pioneer novel neuromodulation-based treatment strategies.
A small study found that five volunteers with late-onset Alzheimer's disease showed significant improvements in cognitive tests and decreased biomarker tau proteins after two years of receiving 40Hz light and sound stimulation. This suggests that the therapy may slow cognitive decline and have direct biological impacts on Alzheimer's p...
A recent study published in PLOS Biology found that combining non-invasive brain stimulation and robotic rehabilitation can significantly improve motor recovery in a mouse stroke model. The treatment restored parvalbumin interneuron dynamics, leading to better motor function.
A recent study published in the British Journal of Sports Medicine found that vision therapy can effectively treat concussion-related eye coordination disorders, including convergence insufficiency and accommodation insufficiency. Nearly 90% of patients in the treatment group were able to see normally after 12 weeks of therapy.
A University of Houston researcher found that recording brain activity while listening to a story can help diagnose primary progressive aphasia, a rare neurodegenerative syndrome. The method was up to 75% effective in classifying the disorder's subtypes using machine-learning algorithms and electroencephalography data.
A new form of electric brain stimulation, HD-tDCS, has been shown to be effective and faster than traditional treatments for depression. Participants who received the therapy reported significant improvements in mood scores, which were sustained during follow-up assessments.
A new ultrasound device has been developed to precisely stimulate areas deep in the brain without surgery, offering new possibilities for neurological research and treatment. The technology features a special helmet with 256 elements that target specific parts of the brain, and includes a soft plastic face mask to keep the head still.
A new study led by University of Waterloo researchers found that female pilots tend to make fewer flight control errors under stress, despite similar visual attention patterns. The findings challenge gender bias in aviation performance and suggest a need for more inclusive pilot training and evaluation systems.
A new study found that safe brain stimulation could help people aged 18 to 30 solve maths problems more efficiently by strengthening connectivity between the dorsolateral prefrontal cortex and posterior parietal cortex.
Researchers have successfully controlled a dexterous robotic hand using noninvasive EEG-based Brain-Computer Interfaces (BCIs) for individual finger movements. The study demonstrates real-time brain decoding and motor imagery control, paving the way for potential applications beyond basic communication to intricate motor control.
Researchers found that passionate fans show more activity in the dorsal medial prefrontal cortex during offensive faceoff opportunities, indicating emotional involvement and evaluative thinking. The study used functional near-infrared spectroscopy to track brain activity in 20 participants watching a professional European ice hockey game.
A new meta-analysis found that symptom provocation before repetitive transcranial magnetic stimulation (rTMS) treatment may enhance clinical response for depression, obsessive-compulsive disorder (OCD), and nicotine dependence. rTMS was nearly twice as effective when symptom provocation was used compared to when it wasn't.
Researchers at the University of Pittsburgh found that mindfulness training and non-invasive brain stimulation can significantly reduce bladder leaks and feelings of urgency evoked by specific environments or scenarios. The study, published in Continence, used transcranial direct current stimulation (tDCS) to activate the prefrontal co...
A new technique using focused sound waves and microbubbles has shown great promise in treating debilitating brain lesions called cerebral cavernous malformations. The approach has halted the growth of lesions almost entirely, offering a potential paradigm shift in treatment.
Researchers from the University of Texas at San Antonio discovered a significant link between REM sleep disturbances and increased PTSD severity. The study suggests that targeting REM sleep could be a promising approach for improving PTSD treatment outcomes.
Researchers at UCSF found clinically significant improvements in mood, cognition, and motor function after psilocybin therapy for patients with mild to moderate Parkinson's disease. The study suggests that psilocybin could provide relief from multiple symptoms of the disease by reducing inflammation and promoting neuroplasticity.
Research finds that 40Hz sensory stimulation promotes broad-based restorative neurological health response in mice with Down syndrome. The study shows improved cognition, increased neural activity, and enhanced neurogenesis, suggesting potential therapeutic benefits.
A new study by Martin-Luther-University Halle-Wittenberg found that brain stimulation can influence decisions, making choices faster with anodal stimulation and slower with cathodal stimulation. The research used transcranial direct current stimulation to activate or inhibit specific brain regions.
Researchers from Syracuse University found potential benefits of transcranial direct current stimulation (tDCS) on attention and fatigue in post-stroke patients, but results were mixed. Participants who received real tDCS showed decreased fatigue, while actual treatment did not improve attention tests.
A team of researchers has identified a common brain network that generalized seizures hijack, which is located in the region where deep brain stimulation (DBS) electrodes are placed. This finding could help explain why DBS is effective in alleviating generalized seizures and potentially improve treatment outcomes.
A team of researchers found bacteria linked to the gut in the brains of mouse models implanted with microelectrodes, breaching the blood-brain barrier. The discovery highlights the need for permanent strategies to prevent bacterial invasion from implanted devices, which can contribute to inflammation and reduced device performance.
The Open Brain Institute launches a groundbreaking platform to simulate and study digital brains, empowering researchers to explore brain complexity and diseases. With its virtual neuroscience laboratories, the OBI enables global collaboration and access to cutting-edge virtual labs.
Researchers at Carnegie Mellon University have developed a new, minimally invasive method called DeepFocus for treating depression and other neural conditions using transnasal electrical stimulation. This technique offers more accurate and efficient targeting of deep brain structures with lower risk.
Studies have consistently shown that 40Hz gamma stimulation can improve cognitive function and reduce Alzheimer's pathology in mice. In human clinical trials, participants exposed to 40Hz light and sound experienced significant slowing of brain atrophy and improvements on some cognitive measures compared to untreated controls.
A new study led by researchers at Mass General Brigham suggests that different brain regions activated by creative tasks are part of one common brain circuit. People with brain injuries or neurodegenerative diseases may have increased creativity due to changes in this circuit.
Researchers studied whether transcranial direct current stimulation could enhance constraint-induced movement therapy for post-stroke motor recovery. The study found no significant improvement in motor skills, despite using three doses of electrical stimulation on 129 stroke survivors. Future trials aim to address limitations and impro...
A new drug-free intervention targets the root cause of progressive loss of neural function in SMA by gradually reawakening functionally silent motor neurons. Early results show improved leg muscle strength and walking in adults with SMA, regardless of symptom severity.
A free webinar by Brain & Behavior Research Foundation presents advancements in neurobiology of fight-or-flight responding and its targeting using noninvasive brain stimulation technologies. The discussion focuses on transcranial magnetic stimulation and focused ultrasound for developing new treatments.
Researchers developed a preclinical model of brain stimulation therapy that enhances the brain's ability to process conflicting evidence. This improvement in cognitive flexibility could lead to more effective treatments for conditions like depression, ADHD, and addiction.
Researchers at DGIST have developed a novel brain stimulation technology using an ultra-small coil to stimulate specific areas of the brain with high precision. This approach eliminates the need for large devices and minimizes risk of brain tissue damage.
Researchers from Kessler Foundation will evaluate the efficacy of Brain.Q's 'Q Therapeutic System' in a two-year study. The therapy involves electromagnetic stimulation and low-intensity fields to optimize brain adaptation and healing after stroke.