Orthopedics

Study finds new ACL surgery approach helps most patients return to activity

New position statement highlights the growing role of genicular artery embolization for knee osteoarthritis

Call for coordinated action to close Africa’s bone health gap

A new editorial by IOF members highlights the alarming high post-fracture mortality in Africa and emphasizes the need for a targeted, Africa-driven strategy. The authors propose five strategic priorities to build bone health into national health systems, education, and policy.

Pioneering study confirms the benefits of total hip arthroplasty

A pioneering study by the University of Eastern Finland confirms that total hip arthroplasty leads to better outcomes than conservative treatment for patients with moderate-to-severe hip osteoarthritis. The surgery significantly improved pain, functional capacity, and quality of life compared to conservative treatment alone.

One of the world’s most common knee surgeries does not help and may even be harmful

A 10-year follow-up study found that partial meniscectomy did not improve patients' symptoms or function, but rather worsened osteoarthritis progression. The study's findings suggest a potential medical reversal, where widely used therapies prove ineffective or even harmful.

UC San Diego Health performs first west coast AI robotic spine surgery

The new robotic system combines artificial intelligence, data-driven alignment planning, patient-specific implants, navigation, and robotic screw delivery to enhance precision and coordination. This technology streamlines operating room workflows, reducing procedure time and supporting recovery for patients undergoing spine fusions.

Global survey reveals significant burden and inconsistent management of hypophosphataemic osteomalacia in adults

A new international survey reveals that adults with hypophosphataemic osteomalacia face a substantial disease burden, often under-recognised. The study calls for improved awareness, education, and coordinated care to ensure timely diagnosis and optimal treatment.

International Osteoporosis Foundation CNS Medal awarded to Professor Radmila Matijevic

Professor Radmila Matijevic received the IOF CNS Medal for her outstanding work in advancing bone health awareness, diagnosis, and management. Her contributions to osteoporosis research and clinical practice have improved patient care in Serbia and the wider Balkan region.

ESCEO-IOF Young Investigator Awards presented to researchers from 16 countries

Twenty-three young investigators from 16 countries received the ESCEO-IOF Young Investigator Awards for their outstanding abstracts submitted to the WCO-IOF-ESCEO 2026 Congress. The awards aim to support and attract young researchers to the field of musculoskeletal research.

Professor Roland Chapurlat receives IOF Olof Johnell Science Award

The International Osteoporosis Foundation has awarded Professor Roland Chapurlat the prestigious IOF Olof Johnell Science Award for his seminal contributions to understanding and managing osteoporosis, osteoarthritis, and skeletal rare bone diseases. He is recognized as one of the leading clinical academics in the field worldwide.

IOF honors Professor Thierry Chevalley with President’s Award

Professor Thierry Chevalley has received the prestigious IOF President's Award for his significant contributions to advancing bone health and osteoporosis prevention. With extensive research expertise in geriatrics and bone health, he serves on various scientific committees and leads efforts to develop fracture liaison services.

IOF CSA Medal of Achievement awarded to Professor Noriko Yoshimura

Professor Noriko Yoshimura has received the IOF CSA Medal of Achievement for her pioneering work on epidemiology and prevention of locomotive organ disorders and osteoporosis. Her research, including the ROAD Study, has significantly advanced understanding of musculoskeletal health.

University of Cincinnati enrolls first patients in clinical trial for prosthetic joint infections

A new clinical trial at the University of Cincinnati is testing a peptide solution to treat prosthetic joint infections after total knee replacement. The trial aims to reduce the need for repeat surgeries and expand the treatment window beyond two weeks.

New research brings joint repair closer for millions with osteoarthritis

A team of researchers has achieved a major milestone in developing a new treatment aimed at helping the body repair damaged joints at the source. The experimental treatments have shown promising results in animal models, restoring joint tissue to near-normal levels and significantly reducing pain markers for long periods.

Review highlights a three-way link between mechanical stress, integrin signaling and endocytosis in osteoarthritis

Researchers identify a three-way link between mechanical stress, integrin signaling, and endocytosis in osteoarthritis. Integrin trafficking may help explain why the same pathways have different effects across disease stages and tissue contexts.

Development of build better bones: A global resource for osteoporosis self management

A new platform, Build Better Bones, offers evidence-based guidance and practical resources for osteoporosis management. The platform, developed by the International Osteoporosis Foundation, provides a trusted place for people with osteoporosis to start their journey, with a focus on exercise, nutrition, and home safety.

Single-cell atlas reveals why rotator cuff injuries heal with damaging scars

Researchers discovered that tendon stem cells and progenitor cells fail to differentiate into mature, functional cells, instead promoting scar buildup. Immune cells, including macrophages, also play a central role in sustaining fibrosis, creating a self-sustaining environment that is difficult to reverse.

LOXL2 enzyme discovery offers new hope for jaw arthritis

Researchers have discovered the protective role of LOXL2 protein in preventing cartilage damage and inflammation in temporomandibular joint osteoarthritis. The enzyme helps suppress inflammatory pathways, reducing cell death and preserving cartilage viability even under inflammatory conditions.

Study reveals multiple types of post-amputation pain, each needing different treatment

Researchers identify three types of post-amputation pain: phantom limb pain, residual limb pain, and musculoskeletal pain, which behave differently and require personalized care. The study's findings suggest that prosthetic design can directly influence comfort during real-world movement, improving mobility and quality of life for indi...

NYU Langone orthopedic surgeons present latest clinical findings and research at AAOS 2026

Researchers at NYU Langone Orthopedics present new study on ACL reconstruction in athletes over 50, finding physiological age determines treatment. They also develop an AI chatbot to answer pre- and postoperative questions, improving patient engagement and education.

Starving cancer: Nutrient deprivation effects on synovial sarcoma

Researchers at Osaka Metropolitan University found that targeting the glutamine transporter ASCT2 can suppress cell growth and induce apoptosis in synovial sarcoma cells. This study suggests a new approach for treating this aggressive malignant tumor by cutting off its nutrient supply.

A holiday to better recovery

A study of 77,947 patients found that those over 80 and with low initial ADL scores benefited from holiday rehabilitation. This suggests prioritizing interventions for elderly and independent individuals can lead to better outcomes.

A non-invasive therapeutic strategy for improving bone healing in aged patients

Researchers identified ApoE as a systemic inhibitor of bone repair during aging, and showed that blocking its activity can restore bone regeneration and improve fracture healing. The study provides hope for therapies that actively restore regenerative capacity in older patients, reducing nonunion risk and improving recovery.

Hidden virus linked to hip bone collapse, offering hope for true prevention of osteonecrosis

A new clinical study identifies localized reactivation of human cytomegalovirus inside the femoral head as a potential cause of osteonecrosis. The findings suggest that antiviral prevention strategies may be effective in blocking disease progression.

New program at UT Health San Antonio delivers breakthrough care for limb loss patients

The new program combines limb preservation, amputation care, and reconstructive solutions like osseointegration to improve identity, functional outcome, and quality of life for patients. Patients will receive coordinated, personalized, and expert care that supports their recovery and promotes sustained overall health.

Orthopedics can play critical role in identifying intimate partner violence

A study highlights the opportunity for orthopedic surgeons to identify patients who have experienced intimate partner violence (IPV), with only 0.3% of referrals compared to 29% from emergency departments. Orthopedic teams can educate and empower patients, providing timely life-saving referrals.

Rice and MD Anderson build patient-specific models to guide complex pelvic cancer surgeries

Researchers at Rice University and MD Anderson Cancer Center developed patient-specific models to predict stress and deformation in reconstructed pelvises. The study found that larger bone grafts experience lower stresses and smaller deformations than thinner bones.

Tackling the burden of osteoporosis and fragility fractures: The APCO-IOF Asia Pacific Regional Audit

The Asia Pacific Regional Audit highlights key trends, gaps, and opportunities in 22 countries and regions. The audit reveals a steep rise in fracture rates due to poor bone health and an ageing population, with China, Malaysia, and Australia experiencing significant increases.

How fast you can walk before hip surgery may determine how well you recover

Researchers found that patients who can walk at least 1 meter per second before hip replacement have significantly better mid-term postoperative outcomes. This simple and reliable predictor could help physicians determine when to refer patients for surgery, and preoperative rehabilitation programs could be developed.

Avoidable cancellation of knee replacement operations costs NHS millions and increases waiting times

A new study reveals thousands of NHS knee replacement operations are cancelled annually for avoidable reasons, costing millions and prolonging waiting times. Lack of available beds and medical ineligibility were the most common causes, with many cancellations avoidable with advance planning.

9th IOF Asia-Pacific Bone Health Conference set to open in Tokyo

The 9th IOF Asia-Pacific Bone Health Conference will bring together healthcare professionals, researchers, and policymakers to exchange knowledge and shape the future of bone health across the region. The conference will feature keynote lectures, sponsored sessions, and a launch of the IOF Asia-Pacific Regional Audit 2025.

Predicting how bones heal

An international team led by Lehigh University researcher Hannah Dailey is building predictive models to understand and eventually prevent bone healing complications. The team aims to incorporate biological differences into the model, using a library of imaging data from Switzerland's AO Research Institute Davos.

Study finds no increased safety risk for obese patients undergoing shoulder replacement surgery

A large-scale study of over 20,000 elective shoulder replacement surgeries in the UK and Denmark found that higher BMI is not linked to increased risk of death or complications. Underweight patients, however, were found to have a slightly higher risk of death.

Researchers redefine hip arthroscopy with breakthrough surgical device

Researchers have developed a new surgical instrument called the CAP-LIFT cannula that completely transforms arthroscopic procedures in the hip region. The device solves existing problems with limited space and allows for easier maneuverability of tools, reducing complications and recovery time.

Successful bone regeneration using stem cells derived from fatty tissue

A team of researchers at Osaka Metropolitan University has successfully treated spinal compression fractures in rats using stem cells derived from adipose tissue. The study found that these cells can promote bone healing and regeneration, making them a potential solution for osteoporotic vertebral fractures.

Built to heal, born to vanish: the promise of iron-manganese alloys in bone healing

Researchers have identified iron-manganese alloys as promising candidates for temporary bone fixation. These alloys combine strength, biocompatibility, and degradation properties, allowing them to support bone healing while degrading naturally. However, challenges remain, including controlling the release of manganese, which can pose t...

Engineering a clearer view of bone healing

A new project led by University of Delaware engineer Michael Hast aims to develop radiation-free imaging techniques that identify problems with bone healing sooner. The team uses 3D computational models and recent advances in magnetic resonance imaging (MRI) to estimate the strength of a healing bone and simulate real-world stresses.

Biomaterial vaccines to make implanted orthopedic devices safer

Researchers have developed a novel vaccine strategy using biomaterial scaffold vaccines to protect against Staphylococcus aureus infections in orthopedic device implants. The vaccines, made with immune cell-attaching molecules and S. aureus-specific antigens, create a beneficial immune response that significantly lowers bacterial burden.

New method noninvasively measures Achilles tendon structure and function in professional dancers

A new noninvasive method uses multi-echo ultrashort echo time MRI and shear wave elastography ultrasound to assess the structure and function of the Achilles tendon in professional ballet dancers. The study found that dancers tend to have more tendon stiffness, which corresponds with prior observations of a training effect.

Simple refinements improve thumb reconstruction post-severe injury

Researchers introduced refinements to a rarely used surgical method, the reverse homodigital dorsoradial flap, for radial thumb defects. The key refinements preserved subcutaneous tissue for venous drainage and left a buffer zone at the arterial pivot point to reduce stress on blood vessels.

One-year outcomes after traumatic brain injury and early extracranial surgery in the TRACK-TBI Study

A cohort study found that early extracranial surgery was associated with adverse outcomes in function, cognition, and disability after moderate-severe traumatic brain injury. The study suggests that further research is needed to determine if surgical timing or other interventions can improve long-term deficits.

Mount Sinai study highlights sex-based pelvic differences’ effect on spinal screw, rod placement during surgical procedures

The study found that males have a narrower pelvis, resulting in a more medial starting point for S2AI screws and poorer rod alignment. Researchers aim to tailor treatment to patients' specific anatomy to improve surgical efficiency and outcomes.

Doctors and nurses are better than AI at triaging patients

Research presented at the European Emergency Medicine Congress finds that doctors and nurses are more accurate than AI in triaging patients in emergency departments. While AI showed some promise in flagging critical cases, its overall accuracy was lower than clinicians' across most metrics.

‘Staggering’ costs of e-scooter injuries are quantified for the first time for hospitals in Ireland

Researchers have quantified the costs of e-scooter injuries for the first time in Ireland, revealing an average cost of €1,726 per patient. The study found that e-scooter injuries mainly resulted in musculoskeletal injuries requiring major surgery, resulting in significant financial burdens on healthcare services.

New models address problems related to timing, scheduling of surgeries, capacity planning, and patients’ stays in recovery units

Researchers developed an integrated approach to solve the elective surgery assignment, sequencing, and scheduling problem (ESASSP), reducing delays and costs. The study suggests that hospitals can benefit from computationally efficient solutions to minimize operational costs and maximize resource utilization.

Mount Sinai researchers find electrical stimulation may help predict recovery path for acute nerve injuries

Researchers found that nerves with a response to stimulation had a greater likelihood of recovering on their own, while those without a response had a low chance of functional recovery. The study uses intraoperative electrical nerve stimulation as a tool to distinguish between recoverable and non-recoverable nerve injuries.

Closing the care gap: IOF position paper identifies barriers and solutions to global undertreatment of osteoporosis

The International Osteoporosis Foundation identifies critical global barriers to osteoporosis care, including limited DXA scanning and outdated treatment criteria. The IOF advocates for a paradigm shift in bone health management worldwide, recognizing high fracture risk as a valid criterion for treatment and reimbursement.

Keith Cole receives grant to conduct integrated research on mobility, cognition and aging

Keith Cole has received a five-year grant from the National Institute on Aging to conduct integrated research on dual decline, mobility, cognition and aging. This research aims to identify predictors and treatment targets for older adults at risk of physical and cognitive decline.

New research highlights critical role of movement in lifelong bone health

A new review emphasizes the importance of both physical activity and reduced sedentary time for optimal skeletal health. Emerging evidence reveals that prolonged sitting and inactivity can harm bone health, even among regular exercisers.

World’s first custom anterior cervical spine surgery

The procedure uses a combination of advanced imaging, artificial intelligence, and 3D printing to create a customized implant tailored to each patient's unique anatomy. This technology allows for more precise spinal alignment, reduced surgical complications, and faster recovery times.

Survey: People not aware knee, groin pain can be signs of hip problems

A new survey by Ohio State University Wexner Medical Center reveals that many people are unaware of the connection between knee, groin, and hip pain. The study found that 72% of respondents were not aware that knee pain could be a sign of a hip problem.

Player position influences risk of ACL tear in the NFL

A new study from the University of Missouri-Columbia found that NFL players who play wide receiver or tight end are at a higher risk of suffering an injury to their anterior cruciate ligament (ACL). The study examined 520 tears over a ten-year period and found that contact injuries and non-contact mechanisms, such as landing from a jum...

Ochsner Children’s performs first robotic-assisted pediatric spine surgery in Louisiana

Pediatric orthopedic surgeons at Ochsner Children's perform the first robotic-assisted pediatric spine deformity surgery in Louisiana using Globus Medical's ExcelsiusGPS technology. The procedure enables unprecedented surgical precision and accuracy, improving patient outcomes.

Mount Sinai returns as official hospital and medical services provider of the US Open Tennis Championships

Mount Sinai will provide orthopedics, sports medicine, emergency medicine, and musculoskeletal radiology services to world's top tennis stars. The institution has partnered with the USTA for 13 years, promoting health and wellness, preventing injuries, and catering to diverse populations.

Study reveals how small changes in walking technique may help treat knee osteoarthritis

A new study suggests that subtly adjusting the angle of the foot during walking can reduce knee pain caused by osteoarthritis and slow its progression. By tailoring each patient's foot angle to their unique walking pattern, experts believe an easy and fairly inexpensive way to address early-stage osteoarthritis may be found.

Genetically engineered mouse model provides insights on genetic bone disorders

Researchers developed a genetically modified mouse model to study osteogenesis imperfecta (OI), a rare genetic bone disorder. The study found that the Sp7 R342C mutation affects bone mineral density, trabecular bone volume fraction, and cortical porosity, leading to impaired bone remodeling.

Removing barriers to recovery improves surgical outcomes

A new study from the University of Missouri School of Medicine found that pre-surgical behavioral evaluations can improve patient outcomes after orthopedic surgery. By identifying and addressing potential barriers to recovery, patients are more likely to follow post-operative plans and achieve successful outcomes.

Groundbreaking resource simplifies spinal biomechanics for residents and students

The new book Spinal Surgery Biomechanics: Principles for Residents offers a comprehensive exploration of core biomechanical concepts essential for mastering spinal surgical procedures. It bridges the gap between theory and practice, providing a biomechanical framework that supports surgical planning and patient safety.

The Mount Sinai Hospital ranked among top in the nation by US News & World Report®

The Mount Sinai Hospital has been listed among the nation's top 20 hospitals for care excellence by U.S. News & World Report for 2025-26, with top-10 rankings in five specialties and top-20 rankings in nine. The hospital was also rated High Performing in all 22 procedures and conditions assessed by U.S. News.

McGrath Outpatient Pavilion opens at UC San Diego Health

The 250,000-square-foot facility provides greater availability to high-quality integrated care, addressing the region's increasing demand for innovative diagnostic and treatment services. The pavilion brings together a broad range of nationally ranked clinical programs, including cancer clinics, neurology, and surgery.