Articles tagged with Carbohydrates
Researchers developed fluorescent molecular probes to detect glucose levels in living animals, enabling real-time visualization of sugar uptake. The technology also enables the detection of elevated glucose in living systems, including zebrafish with diabetes-like mutations.
A clinical trial found that a ketogenic diet significantly improves metabolic health in people with obesity, with 50% of participants no longer meeting the criteria for prediabetes. The diet also showed the greatest improvements in liver health and insulin sensitivity.
A four-million-year study modelled the glucose needs of humans and their ancestors, finding natural sugars supplied energy for growing brains before cooking made starch-rich foods easier to digest. The research suggests earliest hominins were highly reliant on carbohydrate-rich foods, particularly fruit.
Researchers found that genetic factors play a role in how individuals respond to a low-carb, high-fat diet, with those at higher risk experiencing greater increases in LDL cholesterol. The study suggests personalized dietary guidance based on genetic profiles could help identify who may experience adverse responses to certain diets.
A global study found that plant evolutionary history plays a stronger role in shaping nonstructural carbohydrate (NSC) storage than current environmental conditions. NSC variability is organ-specific, with leaf NSCs increasing toward higher latitudes and stem and root NSCs declining.
A recent study identified a new type of β-1,2-glucan-binding protein in bacteria, which binds cyclic β-1,2-glucans and has implications for understanding bacterial interactions with these complex molecules. The discovery opens up new avenues for developing biological pesticides to protect crops from pathogens.
Scientists at Stockholm University and SciLifeLab have uncovered a crucial missing link in how sugar transporters move nutrients into cells. Their study reveals that these transport proteins rely on a previously uncharacterized intermediate state, similar to the 'transition state' in enzyme catalysis.
Researchers found that people following a Mediterranean-style diet have higher levels of humanin and SHMOOSE, which are linked to protection against cardiovascular disease and neurodegeneration. The study suggests that specific components of the Mediterranean diet may directly influence mitochondrial biology.
Scientists at UCSF created a new material that enables more predictable organoid growth, allowing for better study of disease and potential tissue replacement. The dynamic gel, invented by Zev Gartner, mimics the body's soft environment and enables precise 3D printing of stem cells.
A new Cochrane review found that sucrose can effectively reduce pain in newborn babies during painful procedures like venepuncture. The study examined 29 clinical trials involving over 2,700 babies and showed that a small amount of sucrose given before the procedure significantly reduces pain when combined with non-nutritive sucking.
Researchers found that people's expectations about sugar content alter their enjoyment of beverages containing artificial sweeteners. By manipulating participants' expectations, the study shows how the brain's reward system responds to sweet flavors, with increased activation in the dopaminergic midbrain.
A new study finds that the quality of macronutrients matters more than their quantity for heart health, with diets rich in whole grains, fruits, and vegetables associated with a lower risk of coronary heart disease. The study also found improved cardiovascular biomarkers in healthy versions of low-carb and low-fat diets.
A new study found that versions of both diet patterns emphasizing healthy foods are associated with a lower risk of coronary heart disease. The study suggests that focusing on overall diet quality may offer flexibility for individuals to choose eating patterns that align with their preferences while still supporting heart health.
A recent study published in the Journal of Nutrition found that higher fat diets were more harmful than high-carbohydrate diets, even when fiber supplementation was added. Mice on high-fat and ketogenic diets experienced weight gain, liver damage, and other negative health effects, while those on a high-carbohydrate diet did not.
After initiating GLP-1 receptor agonists, consumers showed a decrease in ultraprocessed foods and an increase in protein, while purchasing fewer calories, sugars, and saturated fats. These modest changes may have significant population-level effects given increasing GLP-1RA use.
Researchers develop experimental drugs that encourage mitochondria in cells to work harder and burn more calories. The findings offer a framework for designing safe and effective weight-loss treatments with potential benefits for metabolic health and neurodegenerative diseases.
Researchers at the University of Gothenburg discovered that grey seal milk contains approximately 33% more sugar molecules than breast milk, including unique and powerful compounds against disease-causing bacteria. These findings could lead to improved infant formula and potential applications in human health.
Research found that high-fat and high-carbohydrate diets are controlled by separate neural pathways in the brain. Neuropeptide Y neurons activate AMPK-regulated corticotropin-releasing hormone neurons to promote high-carb intake, while inhibiting melanocortin 4 receptor neurons to increase high-fat intake.
The four-day training program equipped postdoctoral fellows with state-of-the-art methods for clinical research in obesity, metabolism and nutrition. Participants deepened their skills in gold-standard methodologies crucial for advancing clinical and translational research.
Researchers at uOttawa are developing an AI tool to provide personalized dietary strategies for people living with inflammatory bowel disease (IBD). The project aims to match specific types of carbohydrates to individual patients' unique gut microbiomes.
A new study published in Nutrients found that both whole and refined grain foods can contribute to improved dietary patterns and health. The study analyzed data from over 14,000 Americans and identified healthy grain foods based on nutrient density, fiber, protein, and essential nutrients.
Researchers found that measures of glycemic control were more closely linked to changes in food preferences than body weight status. Participants who had fasting glucose and HbA1C at the high end of normal were less likely to prefer flavors paired with nutrients, even if they had a healthy BMI.
Researchers identified hundreds of hidden binding partners for a blood protein receptor, revealing links to organ dysfunction and increased sepsis risk. The study found that Mrc1's absence led to the accumulation of mannosylated proteins, which disrupted normal physiology and function.
A new study suggests that erythritol, commonly used in low-carb products, can alter the function of brain microvascular endothelial cells, leading to increased risk of stroke. The sugar substitute was found to constrict blood vessels and reduce the production of natural clot-busting compounds.
Researchers found that adding partially defatted sunflower seed flour (SF) to bread increased its protein and fiber content. SF also boosted antioxidant levels and showed inhibitory activity against digestive enzymes, promoting health benefits. However, high proportions of SF compromised sensory characteristics.
A novel fluorescent probe, SLY, has been developed to precisely identify hepatocellular carcinoma tissue using sialylated glycans on the cell surface. The probe outperforms conventional methods by clearly distinguishing tumor margins within liver tissues.
A large study followed nearly 200,000 people for several decades to find that choosing healthy, minimally processed foods is key to protecting the heart. Healthy diet patterns, whether low-carb or low-fat, lowered the risk of developing heart disease by about 15%.
A cohort study found that high-quality carbohydrate intake and dietary fiber consumption were positively correlated with healthy outcomes in older adulthood. The study suggests that focusing on carbohydrate quality may be crucial for maintaining overall health as people age.
University of Oklahoma researchers create bioactive sugars to develop novel antibiotics against multi-drug-resistant infections in cancer patients. By using abundant, inexpensive, iron or metal-free, non-toxic blue light, the team can more easily and rapidly synthesize these important carbohydrates.
A systematic review of nearly 6000 runners found that lower energy and fat intakes were strongly associated with a higher risk of injury in female runners. A low-fibre diet also increased the likelihood of bone stress injuries.
A new study by the University of Surrey found that restricting carbohydrates can lead to improvements in metabolic markers and better handling of high-fat meals. This approach may be more sustainable than extreme calorie restriction, reducing hunger and increasing energy burning.
Researchers discover immune cells regulate blood sugar levels by stimulating glucagon production in the pancreas. This complex neuroimmune-hormonal circuit reveals a new way the body maintains stable glucose levels, especially during periods of low energy.
Researchers found specific gene mutations in barley affect starch synthesis, forming elongated starch granules with altered properties. Mutations disrupt enzymes, altering glucose chain formation and branching.
Research at UC Davis found that megafire smoke can lower energy reserves in orchard trees and cut nut production by half, affecting plants for months after the fire. The study suggests that trees are vulnerable to smoke like humans, impacting agricultural and natural environments.
A new study in Frontiers in Nutrition found that well-constructed low-carb eating patterns can meet and sometimes exceed nutrient needs. The study assessed three different 7-day low-carb meal plans, which safely exceeded nutrient needs for vitamins A to K, thiamin, riboflavin, niacin, folate, and vitamins B6 and B12.
A team led by Harvard's Ryan Flynn has discovered the mechanism of how RNA is chemically linked to N-glycans, proving the existence of glycoRNAs. This finding broadens the scope of known glycoconjugates and opens new avenues for research into glycoRNA biology.
A new Cornell University study found that dietary fiber recommendations should be tailored to each person's unique gut microbiome. The research identified two types of resistant starch and found that individuals may respond differently to these foods, with some benefiting from increased fiber intake and others experiencing no effect.
Scientists have created mirror-image cyclodextrins in the laboratory, which could make it easier to formulate and deliver complex medications. These discoveries may also lead to improved treatment of cardiovascular diseases caused by atherosclerotic plaques.
A new study published in Nature Metabolism challenges the common perception that high lactate levels are bad for athletes. Lactate is found to be a normal product of metabolic activity, and it plays a crucial role in managing glucose levels after consuming carbohydrates.
Scientists have designed a synthetic antigen that can stimulate antibody production against cancer cells. The approach uses a natural protein called serum albumin to carry the antigen, reducing the need for bulky carriers and side effects.
A team of scientists from Pohang University of Science & Technology developed an artificial vitreous body based on alginate to treat retinal detachment. The hydrogel maintains vision post-surgery and regulates fluid dynamics within the eye, preventing recurrence and air bubble formation.
A team of University of Copenhagen researchers has created a large reference catalogue of plant cell wall compositions from 287 species, representing the entire plant kingdom. The study reveals that carbohydrate composition is more closely related to a plant's family history than its habitat and growth form.
A scoping review of 508 clinical studies found that most define a low-carb diet as limiting carbohydrate intake to 30% or less, with some using thresholds below 100 grams per day. The study highlights the need for a standardized definition to inform public health and nutrition activities.
A study of 123,000 individuals found that low-carbohydrate diets emphasizing whole grains and plant-based foods are associated with slower weight gain in the long term. Low-carb diets relying on animal-sourced proteins and refined carbohydrates result in faster weight gain.
A new study led by Harvard T.H. Chan School of Public Health found that low-carbohydrate diets rich in plant-based proteins and fats, along with healthy carbohydrates, are linked to slower long-term weight gain. Diets high in animal proteins and unhealthy carbohydrates, on the other hand, are associated with greater weight gain.
A study published in The Journal of Physiology found that exercise suppresses hunger by acting on hormones and metabolites. Researchers suggest that understanding these mechanisms could lead to new treatments for obesity.
Researchers discovered a gut bacteria that helps reduce insulin resistance and protect against diabetes. The study found that a specific bacteria, Alistipes indistinctus, consumed excess monosaccharides in the gut, lowering blood sugar levels and reducing insulin resistance.
A new study suggests that extreme dietary habits, such as low-carb intake in men and high-fat intake in women, are associated with higher mortality risks. The findings indicate that individuals should balance their diet to avoid extremes, while ensuring energy from various food sources.
A collaborative work led by CIC bioGUNE successfully designed and synthesized a carbohydrate sequence capable of folding into a stable secondary structure. The glycans were generated using an automated synthesizer, which rapidly prepared the scaffold, revealing potential new properties for sugars in medicine, catalysis, or nanotechnology.
International researchers have identified nutrient-rich black rice varieties with improved agronomic traits, including shorter stem length and early maturity. These findings provide important resources for crop bioengineers to improve pigmented rice for human health and sustainable agriculture.
A recent study published in GeroScience found that a moderate-protein diet (25% and 35%) improved metabolic health in both young and middle-aged mice. The researchers also observed reduced blood glucose concentrations and lipid levels in liver and plasma. A balanced diet with moderate protein intake may promote metabolic health in huma...
Researchers at Anglia Ruskin University found that a portable breath test can detect changes in metabolism in response to diet. The study used the Lumen device to monitor metabolic fuel use at home and showed that it could detect acute changes in carbohydrate use, but was not sensitive on a day-to-day basis.
The study analyzed the growth and productivity of Botryococcus terribilis under different cultivation systems. Stress increased the production of lipids and hydrocarbons by 49% and 29%, respectively, while proteins decreased. The microalgae's metabolites have potential applications in biofuel synthesis, cosmetics, and food.
A retrospective study found that elevated CA 19-9 and CEA levels were associated with worsened outcomes in duodenal adenocarcinoma patients. The study, which included 68 patients, suggests that these tumor markers may show promise as prognostic tools for this rare malignancy.
The American Society for Biochemistry and Molecular Biology annual meeting will explore cutting-edge approaches in biochemistry and molecular biology. Leading experts will discuss the latest discoveries and advancements in fields such as AI, RNA regulation, and carbohydrates in health and disease.
A 'keto-like' diet, characterized by low carbohydrates and high fat intake, has been linked to higher levels of LDL cholesterol and a twofold increased risk of cardiovascular events. Regular consumption of this diet was associated with an average increase in blood LDL cholesterol levels over 11.8 years.
A new study found that a plant-based low-carbohydrate diet is associated with lower all-cause mortality among people with type 2 diabetes. The study, published in Diabetes Care, analyzed data from over 7,000 participants and found that such diets reduced mortality by 24%.
A new study published in Clinical Gastroenterology and Hepatology found that nearly 1 in 7 Americans experience bloating on a weekly basis. Women were more than twice as likely as men to report feeling bloated, and lifestyle changes, such as exercise and dietary modifications, can help manage symptoms.
A new study from the University of South Australia found that eating 30-50 grams of almonds can help people cut back on kilojoules consumed each day. This leads to a reduced energy intake by 300 kilojoules, mostly coming from junk food.
A 6-month randomized clinical trial found that a low-carbohydrate diet intervention resulted in larger reductions in hemoglobin A1c (HbA1c) levels compared to usual diet among adults with elevated untreated HbA1c. The study suggests that this dietary approach may be useful for preventing and treating type 2 diabetes.