Type 1 Diabetes
Articles tagged with Type 1 Diabetes
New study finds higher dementia risk in insulin-requiring diabetes
Plant-based diet cuts climate impact by more than half, randomized clinical trial shows
A new study published in Current Developments in Nutrition shows that adopting a low-fat vegan diet can rapidly reduce environmental impact while improving metabolic health. The 12-week randomized clinical trial found dramatic reductions in greenhouse gas emissions and cumulative energy demand.
Predicting genetic risk for Type 1 diabetes just got more accurate thanks to UC San Diego study
The study demonstrates that the T1GRS tool can identify children and adults at high risk for Type 1 diabetes earlier than current methods, enabling preventive measures before the disease develops. The researchers grouped individuals into four sub-types based on genetic features, each with unique clinical profiles and outcomes.
Rice Biotech Launch Pad receives award for research to advance cell-based therapy for Type 1 diabetes
Researchers at Rice Biotech Launch Pad are developing an encapsulation platform to protect transplanted pancreatic islet cells from immune attack. The approach aims to reduce scarring and inflammation, making it possible for people with Type 1 diabetes to manage their condition without long-term immunosuppression.
Metabolic risk factors and clinical presentations of metabolic dysfunction-associated steatotic liver disease using data from the all of US research program
Metabolic dysfunction-associated steatotic liver disease (MASLD) affects approximately 32% of the US adult population. Obesity was identified as the strongest independent MRF among Asians, Whites, and Hispanics, particularly in individuals younger than 50 years, whereas hypertension was the strongest independent MRF in Blacks.
World Hormone Day 2026
The European Society of Endocrinology organizes World Hormone Day to educate the public about hormone-related health issues. Global endocrine disorders affect millions worldwide, emphasizing the need for proper hormone balance.
Stanford scientists cure diabetes in mice with increasingly gentle pre-transplant treatment
Researchers at Stanford Medicine successfully cured Type 1 diabetes in mice by combining a blood stem cell and pancreatic islet cell transplant with a gentler pre-transplant treatment. The approach resulted in an immune system made up of cells from both the donor and recipient, preventing disease progression and cure.
Progress in stem cell therapy for type 1 diabetes
Scientists at Karolinska Institutet have created a new method to produce insulin-producing cells from human stem cells, effectively regulating blood sugar levels in laboratory tests and reversing diabetes in mice. The optimized production process yields more mature and purer cells, demonstrating their potential for future treatments.
Research spotlight: High‑fat diets linked to rapid decline in protective gut immune cells
A preclinical study found that short-term high-fat diet exposure rapidly depletes critical gut immune cells called ILC3s, leading to intestinal permeability and inflammation. The loss of these cells compromises intestinal barrier function and may contribute to chronic diseases linked to inflammation.
Implantable islet cells could control diabetes without insulin injections
MIT researchers create an implantable device containing insulin-producing cells that survive in the body for at least 90 days, producing enough insulin to regulate blood sugar levels. The device's improved oxygen generator and electronics enable longer cell lifespan and increased insulin production.
Endocrine Society endorses bipartisan bill to address insulin affordability
The Endocrine Society supports the INSULIN Act to address insulin affordability, setting a $35 monthly cap for people with private insurance and creating a program for uninsured individuals. The bill aims to reduce insulin prices by encouraging competition in the market.
Landmark diabetes trial tests new treatments to bring back ‘hypo’ awareness
A landmark trial is underway to test new treatments that restore the body's natural warning signs for low blood glucose in people with type 1 diabetes. The CLEAR trial compares innovative treatments, including an artificial pancreas system and bespoke psychoeducational programs, to find the most effective way to prevent severe episodes.
100,000 participants screened for early-stage type 1 diabetes in the EDENT1FI project
EDENT1FI has screened 100,000 children across Europe for early-stage type 1 diabetes, using standardized screening programs and harmonized data collection. The initiative aims to empower families to manage life with type 1 diabetes effectively and support children and adolescents with early-stage detection.
$3.4 million grant to improve weight-management programs
A $3.4 million NIH grant will fund a semi-automated feedback system to support people tracking diet, exercise, and weight in weight-management programs. The system aims to provide personalized feedback to increase tracking and weight loss success.
Bringing diabetes treatment into focus
Researchers at Kyoto University developed a PET tracer to quantify beta cell mass in type 1 diabetes patients, revealing lower uptake in those with the disease. This measurement was inversely related to hemoglobin A1c and total daily insulin dose, suggesting its potential as a noninvasive readout of residual beta cell mass.
University of Limerick, Ireland, research reveals challenges of living with gestational diabetes
A study from the University of Limerick found that supportive partners play a crucial role in women's experiences of gestational diabetes, with inadequate support increasing the burden of the condition. The research suggests that knowledge, communication, and cultural context are essential factors in determining the effectiveness of pa...
Pennington Biomedical researcher publishes editorial in leading American Heart Association journal
A Pennington Biomedical researcher published an editorial on the benefits of fruit intake for vascular health, citing a study on increasing fruit intake with avocados and mangos. The findings suggest that diets rich in fruits can improve nutrient status and health outcomes, aligning with the goals of the Food Is Medicine initiative.
UCF researcher developing new therapy to treat diabetic neuropathy
A UCF researcher is pursuing innovative approaches to treat diabetic neuropathy without relying on pain pills and anti-depressants. Dr. Jim Nichols is investigating overlooked mechanisms in the body that may show how insulin deficiency affects sensation in limbs.
Syzygium jambolanum extracts show promising protective effects in diabetes management
Syzygium jambolanum extracts demonstrate significant protective and antidiabetic effects, improving glycaemic control and metabolic health. The study reveals a systemic protective effect beyond glucose lowering alone.
ESE and ESPE launch joint transition of care guidance to improve outcomes for young people moving from child to adult endocrine care
The ESE and ESPE have launched a landmark Joint Clinical Practice Guidance to support structured and effective transition of young people with endocrine conditions. The Guidance provides practical, evidence-based recommendations to ensure continuity, safety and quality of care during this critical phase in a patient's life.
A gel for wounds that won’t heal
Researchers developed an oxygen-delivering gel to heal chronic wounds that fail to heal for more than a month. The gel conforms to the wound's shape and provides continuous oxygen levels, helping transform nonhealing wounds into normal injuries.
Physical inactivity drives a significant share of diabetes complications worldwide; new global study finds
A new global study finds that physical inactivity is a significant driver of diabetes complications, with up to 10% of cases potentially preventable. The research emphasizes the need for tailored approaches to promote physical activity among people with diabetes, particularly addressing social and gender inequalities.
Markers at birth may help predict type 1 diabetes
Scientists at the University of Florida and Linköping University discovered protein markers in umbilical cord blood associated with future insulin-dependent diabetes. The study suggests that these markers can be used to predict type 1 diabetes in early childhood, potentially allowing for targeted interventions and lifestyle changes.
Produce prescriptions improve nutrition for medicaid patients with diabetes
A produce prescription program improved nutrition security among Medicaid patients with diabetes, increasing it from 23.2% to 38.7%. The program also improved food security, with 42.9% of participants reporting secure access to healthy foods after completion.
National childhood type 1 diabetes screening is effective and could prevent thousands of emergency diagnoses, UK study shows
A UK-wide childhood screening program for type 1 diabetes has been shown to be effective in detecting early stages of the disease. By identifying children at risk, families can prepare for a potential diagnosis and receive timely treatment, reducing the need for emergency hospitalizations.
Research reveals B cells’ more sinister role in progression of Type 1 diabetes
A groundbreaking study reveals B cells' detrimental role in progressing Type 1 diabetes by interfering with regulatory T cells. The findings suggest targeting B cell-Treg interactions could offer new therapeutic strategies for preserving beta cells and improving patient outcomes.
Pregnancy-related high blood pressure varied among Asian, Pacific Islander subgroups
Research highlights racial-ethnic differences in pregnancy-related high blood pressure risk, with Pacific Islanders and Filipinos more likely to develop a hypertensive disorder. Early identification and treatment can help prevent serious complications for both pregnant individuals and their infants.
Health issues linked to cosmetic jab complications
A study by Anglia Ruskin University found that patients with underlying conditions such as type 1 diabetes are at a significantly higher risk of complications from cosmetic botulinum toxin injections. The researchers recommend restricting administration to medically qualified professionals.
Newly discovered gut microbial molecules in infancy may influence the risk of type 1 diabetes
A study of over 300 stool samples found that gut-microbe-derived bile acids may play a role in shaping the immune system during early childhood. The findings suggest an imbalance in how gut microbes co-produce these compounds, which could link to signs of type 1 diabetes.
Reprogramming immunity to rewrite the story of Type 1 diabetes
Researchers at the Medical University of South Carolina are developing a new therapy for Type 1 diabetes that combines stem cell biology, immunology, and transplantation science. The goal is to restore beta cell function and insulin production in people with T1D without using immunosuppressive drugs.
Predicting who is at risk of developing type 1 diabetes, as new drugs now available
A genetic risk score test can predict who is at highest risk of developing type 1 diabetes and identify adults eligible for new drug teplizumab. The test identifies those in the top ten percent as eight times higher risk, enabling early intervention and treatment.
New UCF mobile health clinic increases access to care
The UCF Health Mobile Health Clinic provides free high-quality healthcare services to underserved communities, serving as a real-world classroom for medical and nursing students. The clinic aims to reduce preventable conditions and improve long-term health through comprehensive screenings, chronic disease monitoring, and education.
People with diabetes face higher risk of sudden cardiac death
A large study found that people with type 1 and type 2 diabetes have a higher risk of sudden cardiac death, particularly in younger adults. The research also showed that sudden cardiac death contributes to shorter life expectancy for those with diabetes.
Individuals with diabetes are more likely to suffer complications after stent surgery
A nationwide observational study from SWEDEHEART reveals that patients with type 1 diabetes have a significantly higher risk of stent complications compared to those without diabetes. The study emphasizes the need for adapted treatment and follow-up strategies for this patient group.
The future of type 1 diabetes: Can stem cells provide a cure?
Researchers explore innovative avenues for regenerating functional β-cells using stem cells and pancreatic progenitor cells. The dual approach of activating endogenous progenitors and transplanting externally differentiated cells represents a powerful, scalable strategy for T1D management.
Possible therapeutic approach to treat diabetic nerve damage discovered
Researchers at University of Cologne identify p35-mediated CDK5 hyperactivity as a central mechanism limiting nerve regeneration in diabetes. Targeted interventions using peptides restore nerve fiber growth, leading to significant motor and sensory improvements.
New report presents recommendations to strengthen primary care for Latino patients with chronic conditions
The report emphasizes the importance of pairing research with policy partners and investing in mentorship and career advancement of Latino scientists and students. It also calls for implementing evidence-based practices, using telemedicine and AI equitably, and designing trauma-informed interventions that fit Latino family life.
Immune cells ‘caught in the act’ could spur earlier detection and prevention of Type 1 Diabetes
A new study has caught immune cells 'in the act' in pancreatic lymph nodes, suggesting an early onset of Type 1 Diabetes. The researchers identified a unique subset of CD4 T cells that ramp up two proteins, NFKB1 and BACH2, turning genes on and off to rev up the immune attack on insulin-making cells.
USC study suggests type 1 diabetes may significantly raise bladder cancer risk
Researchers found a significant link between type 1 diabetes and an increased risk of bladder cancer, with people being 4.29 times more likely to develop the disease. The new analysis controlled for tobacco smoking, a factor that obscured the heightened risk in earlier studies.
Type 1 diabetes cured in mice with gentle blood stem-cell and pancreatic islet transplant
Researchers at Stanford Medicine have successfully transplanted a hybrid immune system into mice with Type 1 diabetes, preventing the disease from progressing. The approach involves adding a drug to the pre-transplant regimen, which resulted in all mice being cured or prevented from developing the disease.
Improving health during pregnancy for those with Type 1 diabetes
A new insulin delivery technology has been found to improve glucose control during pregnancy for women with Type 1 diabetes, reducing the risk of complications for both mother and baby. The study, led by University of Calgary researchers, found that this technology resulted in a three-hour per day improvement in the desired glucose ran...
Sons of mothers with type 1 diabetes show early signs of vascular dysfunction
A new study reveals that sons born to mothers with type 1 diabetes show early signs of vascular dysfunction in their blood vessels, even before metabolic health is affected. The research suggests that this sex-specific effect could help clinicians assess risk and prevent cardiovascular disease earlier in life.
New milestone towards personalized prevention of type 1 diabetes
The POInT trial reveals promising secondary findings: oral insulin delays clinical type 1 diabetes progression, especially in children with high-risk insulin gene variants. This opens doors to targeted, personalized prevention strategies for a genetically defined subgroup of children.
Effectiveness of anti-clotting meds after stent placement varied in people with diabetes
Researchers found that prasugrel may offer an advantage over ticagrelor for individuals with Type 1 or Type 2 diabetes and complex coronary disease. This is because the two medications are not interchangeable, and treatment with prasugrel may provide better benefits in preventing blood clots and adverse cardiac events.
Human stomach cells tweaked to make insulin to treat diabetes
Researchers successfully converted human stomach cells into insulin-secreting cells in mice, helping to control blood sugar levels and alleviate diabetes. The approach could potentially be used to treat patients with lost or dysfunctional pancreatic beta cells.
Maternal type 1 diabetes may protect children through epigenetic changes
A new study found that maternal type 1 diabetes is associated with specific epigenetic marks in the child, which affect immune function and expression of genes involved in autoimmune diseases. These changes appear to protect against islet autoimmunity, a precursor to type 1 diabetes.
Health benefits of telemedicine in type 1 diabetes
A study at the University of Gothenburg found that intensive treatment with remote monitoring of glucose levels and weekly healthcare contact significantly improved long-term blood glucose control in people with type 1 diabetes. The treatment also increased patient satisfaction and proved to be safe, with no serious events reported.
AI-powered diabetes prevention program shows similar benefits to those led by people
A new study published in JAMA demonstrates that an AI-powered lifestyle intervention app for prediabetes can reduce the risk of diabetes similarly to traditional, human-led programs. The app achieved higher rates of program initiation and completion compared to traditional programs.
Type 1 diabetes increased among young people during the pandemic
A study found a significant increase in type 1 diabetes cases among children under five and young adult men in Sweden during the Covid-19 pandemic. The incidence of diabetes increased by 12% in 2021 and 9% in 2022 compared to previous years, with no clear connection between Covid-19 infection and diabetes.
Vegan diet helps people with type 1 diabetes cut insulin costs by 27%
A low-fat vegan diet has been shown to improve insulin sensitivity and reduce the amount of insulin needed in people with type 1 diabetes. This can lead to significant cost savings, with total insulin costs decreasing by 27% in a recent study.
New ‘smart insulin’ shows promise in reducing hypoglycemia bouts
A new lab-designed protein has been discovered to regulate blood glucose levels, offering a potential new treatment avenue for people with Type 1 diabetes. The substance combines insulin and glucagon into one molecule, signaling the liver to respond naturally.
Diabetic teens with high blood sugar have higher neuropathy risk in adulthood
Poor blood sugar control in adolescence increases the risk of painful future complications for people with type 1 diabetes. Children diagnosed with type 1 diabetes at a young age have trouble controlling their blood sugar as teens and are more likely to develop neuropathy in adulthood.
New estimates predict over 4 million missing people who would be alive in 2025 if not for inadequate type 1 diabetes care
The study predicts that 513,000 new cases of T1D will be diagnosed worldwide in 2025, with the greatest increases expected in Africa and the Middle East/North Africa. The analysis reveals substantial global inequities in diabetes care and outcomes.
Study reports potential effects of verapamil in slowing progression of type 1 diabetes
The Ver-A-T1D trial suggests that verapamil could preserve beta-cell function in adults with newly diagnosed type 1 diabetes. The study demonstrated encouraging trends towards beta-cell preservation and well-established safety profile, but narrowly missed statistical significance.
Fresh hope for type 1 diabetes as daily pill that slows onset confirms promise at 2-year follow-up
A daily pill of baricitinib, a Janus kinase inhibitor, preserves insulin-producing beta cell function and slows type 1 diabetes progression in people recently diagnosed with the condition. The treatment's therapeutic effect is lost when it's stopped, justifying its testing in earlier stages to prevent or delay clinical diagnosis.
An old drug, in a low dose, shown to be safe and effective in preventing progression of type 1 diabetes in children and young people (MELD-ATG trial)
A new trial has shown that a lower dose of the immunomodulatory drug ATG is safe and effective in preventing the progression of type 1 diabetes in young people. The study found that the drug was able to arrest or delay the progression of T1D at a dose as low as 0.5mg/kg, with a good safety profile.
NIH funds study of type 1 diabetes development
A four-year NIH grant will support a study of type 1 diabetes, led by Dr. Shuibing Chen at Weill Cornell Medicine. The researchers will investigate the interplay between genetic and environmental triggers using advanced laboratory and computational tools.
UI Health performs first islet cell transplant with Lantidra
Lantidra, the only FDA-approved therapy for brittle type 1 diabetes, allows patients to stop taking daily insulin injections. The treatment has been shown to preserve health and prevent complications associated with diabetes.
Pennington Biomedical opens Advanced Endocrinology and Diabetes Clinic
The Pennington Biomedical Research Center has opened a new Endocrinology and Diabetes Clinic in Baton Rouge, providing specialized care for patients managing diabetes and endocrine disorders. The clinic is led by Dr. Timothy Gilbert, who brings nearly 20 years of private practice experience to the region.