The review compiles 243 flavonoids from Erythrina species, showcasing structural diversity and biological activities. Flavonoids from this genus have been found to exhibit novel and unusual chemistry, with a focus on prenylated and oxygenated compounds.
Researchers develop a dual-ligand passivation strategy to achieve robust and ultralow-energy thiol-ene click chemistry for direct QD photolithography. The approach results in record resolution and high electroluminescent performance, with potential industrial impact.
Organic chemistry is challenging AI researchers to think outside the box, driving advances in how AI represents complex problems and reasons from limited evidence. This is enabling the development of more reliable, efficient, and transparent AI systems that can support various areas of science and society.
Scripps Research will establish an open-access autonomous chemistry laboratory with a $19.5 million NSF award, advancing AI-driven discovery and education in chemistry. The lab will utilize AI and automation to streamline chemical reaction discovery and optimization, making it more efficient and accessible to a broader community.
A comprehensive review maps twenty years of progress in green analytical chemistry, evaluating tools for measuring environmental soundness. It argues that a single tool is insufficient and calls for an integrated multi-metric approach to cover environmental, safety, and resource footprint.
Advincula, a Governor's Chair Professor at ORNL and University of Tennessee, recognized for research advancing applied chemistry and translating scientific discoveries into practical applications. His work helps strengthen American innovation and industrial competitiveness.
Researchers developed a molecular model for the buckled dimer on semiconductor surfaces, enabling easier analysis of properties and functionalization possibilities. This breakthrough could optimize semiconductors for future technology.
Researchers design a vapor-controlled reversible host–guest chemistry system that controls the optical and physical properties of a functional molecular liquid. The FML's optical and physical properties change immediately upon forming a host–guest complex, but can be restored by exposing it to hexane vapors.
The ENCECO Youth Talent Program provides one-year Young Scholar Support Plan, Journal Expert Training Program, and honorary certificate to outstanding early career researchers in environmental chemistry and ecotoxicology. The program aims to foster collaboration, knowledge exchange, and the next generation of editorial talent.
Yang's research group and collaborators develop a new reaction mechanism that employs photochemistry and metalloenzyme catalysis to form carbon-carbon bonds. This method enables the creation of molecules with multiple stereogenic centers, crucial for pharmaceuticals and agrochemicals.
The study demonstrates how environmentally responsible strategies can be integrated into chemistry classes while maintaining academic rigor. Students at Georgia State University conducted a redesigned experiment as part of their coursework, experiencing green chemistry concepts directly in the lab.
Professor Tony James has been awarded Honorary Fellow of the Chinese Chemical Society in recognition of his significant contributions to fluorescence chemical sensing, molecular identification, and diagnostic chemistry. He is a renowned expert in supramolecular chemistry and chemical sensing with broad international influence.
Researchers have developed molecular cages that encase tetrazine, allowing for specific targeting of cancer cells for imaging and drug delivery. This technology enables precise spatial control over chemical reactions in living systems, promising improved outcomes for patients with limited side effects.
Professor Marc Koper has been recognized for his pioneering research in electrochemistry and catalysis, crucial for developing sustainable energy technologies. His team's theoretical models explain copper's pivotal role as a catalyst in converting CO2 into hydrocarbons.
Researchers from OIST have reported the first full structural characterization of a doubly ring-slipped reaction intermediate in metallocene formation. This discovery provides new evidence on how metallocenes form and react, presenting opportunities for designing tunable structures for applications such as drug delivery systems, cataly...
Gagliardi's work on multireference electronic-structure theory has led to breakthroughs in catalysis, carbon capture, and water harvesting. Her development of MC-PDFT and LAS methods has facilitated the design of materials that function as molecular sponges.
Researchers aim to develop novel quantum algorithms for molecular simulation, targeting computational bottlenecks in drug discovery. The collaboration combines expertise in quantum chemistry and sampling techniques with quantum computing capabilities.
A new report by Change Chemistry and UMass Lowell identifies the need for targeted government incentives to help businesses transition to more sustainable chemicals. The report details how carefully designed incentives can reduce risk, accelerate commercialization, and drive real market adoption.
Manchester scientists discovered a new type of aromatic molecule made entirely of metal atoms, with a tiny ring of three bismuth atoms supporting circulating currents like benzene. The finding bridges the gap between organic and all-metal aromaticity, offering insights into chemical bonding.
A University of Tokyo team developed a fluorescence imaging method to track short-lived molecular intermediates and their magnetic responses in real time. The approach isolates spin-dependent part of chemistry, revealing how magnetically sensitive intermediates appear and disappear.
Researchers have demonstrated a world-leading classical simulation of iterative quantum phase estimation circuits for quantum chemistry on up to 1,024 GPUs, expanding the scale of molecular systems available for the development and validation of quantum algorithms. This achievement supports progress toward industrial applications in dr...
Binghamton University Distinguished Professor M. Stanley Whittingham has been elected as an AAAS Fellow for his groundbreaking work on intercalation chemistry and its applications to lithium-ion batteries. This honor recognizes his contributions to advancing science and promoting scientific progress.
The team developed an air-stable chiral phosphine-catalyzed approach to synthesize enantioenriched S(IV)-stereogenic vinyl sulfinamides, a promising class of antiviral compounds. These compounds exhibit potent binding activity against the mutant SARS-CoV-2 spike protein and HIV-1 ENV protein.
Researchers have confirmed the existence of a long-theorized molecule in oxidation, which has implications for atmospheric chemistry, biochemistry, and medicine. The discovery was made using a unique mass-spectrometric technique and has significant implications for understanding reaction steps and products in oxidation processes.
Researchers at NYU's Department of Chemistry have discovered a way to assemble complex DNA structures without sticky ends, using shape alone to guide assembly. This breakthrough enables the creation of varied 3D structures made entirely out of DNA, with potential applications in optical, electronic, and biomedical technologies.
Researchers have developed a new chemistry-based strategy to localize therapeutic drugs to tumors, reducing harm to healthy tissues. The 'lock-and-key' system uses biorthogonal supramolecular chemistry to release drugs in specific locations, offering a potential path to safer and more precise cancer treatment.
A Brazilian research team used non-formal education methods in science museums to improve high school students' interest and confidence in chemistry. The interactive exhibition explained advanced oxidation processes, increasing students' sense of competence and positive perception of the discipline.
Researchers at UCLA have developed cage-shaped, double-bonded molecules called cubene and quadricyclene that defy expectations by breaking the traditional rules of organic chemistry. The discovery has potential applications in drug development, enabling the creation of more complex 3D structures for new medicines.
Scientists at the University of St Andrews have discovered a long-elusive molecular 'reshuffle,' unlocking an 80-year-old chemical puzzle. This breakthrough tackles one of chemistry's most persistent challenges, enabling faster, cleaner, and more selective ways to manufacture complex molecules with a single handedness.
Researchers from Tokyo University of Science developed an efficient strategy to synthesize PROTACs using a three-step click chemistry method. This approach rapidly assembles functional molecules, enabling the easy introduction of ligand components and probe functionalities.
The new book provides a comprehensive overview of medicinal chemistry and target-based drug design for diseases such as leishmaniasis, Chagas disease, malaria, and others. It highlights emerging therapeutic compounds and the integration of synthetic and computational approaches to drug discovery.
Ten Scripps Research scientists, spanning chemistry, microbiology, immunology, and more, have been recognized on Clarivate's Highly Cited Researchers list. The list highlights researchers whose publications rank in the top 1% by citations for their field and publication year.
Dr. Anna Wuttig, a UChicago chemist, receives the award for her innovative work on electrocatalysis for energy storage and conversion, as well as medicinal chemistry. Her lab develops new concepts that integrate physical and synthetic inorganic and organic chemistry to enhance catalytic reactions.
Researchers found that methane, ethane, and hydrogen cyanide can interact in ways previously thought impossible, expanding our understanding of chemistry before life emerged. This discovery has implications for the origin of life on Earth and may shed light on similar conditions in other cold environments in space.
Han Xiao, a pioneer in medicinal chemistry, has been awarded the David W. Robertson Award for his contributions to therapeutic discovery. His research focuses on developing chemical tools to probe and manipulate biological systems, with a focus on cancer therapy.
Researchers at WashU have gained unprecedented views of a protein linked to ALS and FTD, revealing unique shapes that may contribute to disease progression. The discovery opens doors to new approaches for treatment and prevention, with the team planning further experiments to understand the protein's role in health and disease.
Researchers analyze the 'dead Mn' dilemma in MnO2 chemistry, proposing strategies to enhance electrochemical reversibility and cycling stability. Mitigation approaches include optimizing deposition conditions, regulating proton supply, and reactivating inactive species using redox mediators.
The American Chemical Society's President Dorothy J. Phillips congratulates Susumu Kitagawa, Richard Robson, and Omar M. Yaghi on their Nobel Prize in Chemistry win for developing metal-organic frameworks. This award highlights the power of chemistry to address global challenges through international collaboration.
Lucy Shapiro, a pioneering biologist and advocate, is awarded the Lasker-Koshland Award for her life-changing trajectory in chemistry and biology. Her work on bacterial compartmentalization has overturned prevailing ideas and paved the way for new discoveries.
Researchers have developed a new catalysis method that can generate a diverse array of valuable compounds, including six distinct molecular scaffolds, using reprogrammed biocatalysts and sunlight-harvesting catalysts. The method opens up new possibilities for medicinal chemistry and accelerates combinatorial synthesis of novel molecules.
Angel Martí, David Sarlah, and Haotian Wang have been honored with national American Chemical Society awards for their outstanding work in chemistry. The ACS awards recognize individuals who not only advance the field but also inspire students from underrepresented backgrounds to pursue careers in chemical sciences.
The team created Pd5AlI2, a metallic material that exhibits frustration of electron motion due to its chemistry, rather than geometry. This discovery opens up new possibilities for flat bands and unique electronic structures that could lead to breakthroughs in quantum technologies like superconductors and rare-earth-free magnets.
Scientists have isolated methanetetrol for the first time, an ortho acid thought to play a key role in early life chemistry. The compound is highly unstable but can release important compounds when given energy.
A research team at Politecnico di Milano has created a single-atom catalyst capable of selectively adapting its chemical activity. The catalyst, composed of palladium encapsulated in an organic structure, can 'switch' between two key reactions in organic chemistry by varying reaction conditions.
Recent advances in chemistry have led to innovations in industrial carbon capture technologies, reducing energy consumption by over 30% and improving efficiency. The research highlights novel amine blends, metal-organic frameworks, and electroswing technologies that can selectively capture CO2 with high efficiency.
Dr. Phil Costanzo, a Cal Poly chemistry professor, has been recognized with the Jack Flack Norris Award for his contributions to chemistry education. He co-founded the Macromolecular Alliance for Community Resources & Outreach (MACRO), a joint service committee that provides freely accessible educational resources for polymer chemists.
Researchers at OIST have synthesized a stable 20-electron ferrocene derivative, defying the traditional 18-electron rule. This breakthrough could lead to new applications in energy storage, chemical manufacturing, and sustainable chemistry.
The Stockholm Declaration on Chemistry for the Future emphasizes the need to integrate health and sustainability in chemical products and processes. It calls for action from scientists, industry, educators, students, and policymakers to collaborate on implementing solutions that balance human well-being with environmental protection.
Göttingen University researchers have discovered previously undetected chemical bonds within archived protein structures, revealing an unexpected complexity in protein chemistry. These newly identified nitrogen-oxygen-sulphur (NOS) linkages broaden our understanding of how proteins respond to oxidative stress.
Manuel Souto received the Young Researcher Award from the Spanish Royal Society of Chemistry for his leadership of the ElectroMolMat research group at CiQUS. The award recognizes his outstanding professional achievements and contributions to electroactive molecular materials.
Rasika Dias, a renowned chemist at UTA, has been named a 2025 fellow of the Royal Society of Chemistry for his groundbreaking contributions to chemical sciences. He is the second chemistry faculty member to receive this honor.
Researchers have developed novel methods for aerobic oxidation of organic compounds using molecular oxygen or air as green oxidants. Photocatalysis, electrocatalysis, and photoelectrocatalysis technologies offer new insights for sustainable chemical synthesis and development.
Researchers at the University of Texas at Dallas have developed a durable and recyclable foam that can be 3D-printed using dynamic covalent chemistry. The new material has reversible bonds, allowing it to repair itself when damaged, making it more versatile and longer-lasting.
A new enzyme discovered can extract high-value molecules from lignin, a forestry by-product, using a hydrogen peroxide-driven process. This breakthrough could support the development of green chemistry 'enzyme factories' to produce valuable chemicals.
Researchers uncovered two electron-transfer mechanisms producing hydroxyl radicals, crucial in atmospheric chemistry. The findings reshape our understanding of acid-base chemistry and have implications for air quality, climate science, and biomedical processes.
Angel Martí, a leading researcher on chemistry and nanostructures, has been awarded the Robert Holland Jr. Award for his groundbreaking work. He is recognized for his contributions to advancing scientific discovery and fostering talent in STEM fields.
Dr. Alison Altman, a Texas A&M chemist, has received the NSF CAREER Award to support her research on underexplored elements of the periodic table and their applications in technology. She aims to expand chemistry education at all levels, emphasizing its impact on everyday life.
A team from Tokyo University of Science developed a novel trivalent platform for triple click chemistry, allowing for the efficient synthesis of complex compounds. The approach utilizes simple initial materials and promotes sustainable pharmaceutical synthesis.
Naomi Halas' work has pioneered new insights into how light and matter interact at the smallest scales, leading to discoveries in biomedical applications such as cancer therapy and water purification. Her research on plasmonic catalysts could dramatically reduce energy required for chemical reactions.
Daniel Armstrong, a renowned UTA chemist, has been honored with the prestigious 2025 Pittcon Analytical Chemistry Award for his pioneering work in analytical chemistry. His research focuses on developing new approaches to identify chiral disease biomarkers, peptide epimers, and isotopic compounds.